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Review Article
| Open AccessGlycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases
- Sehyun Oh
- , Xuan Linh Mai
- & Sunghyouk Park
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Review Article
| Open AccessNeutrophils and neutrophil extracellular traps in oral health and disease
- Tae Sung Kim
- & Niki M. Moutsopoulos
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| Open AccessTetrahydrobiopterin metabolism attenuates ROS generation and radiosensitivity through LDHA S-nitrosylation: novel insight into radiogenic lung injury
- Yang Feng
- , Yahui Feng
- & Shuyu Zhang
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| Open AccessStress-induced epinephrine promotes hepatocellular carcinoma progression via the USP10-PLAGL2 signaling loop
- Chen Wang
- , Jiaping Ni
- & Weiwei Hu
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| Open AccessGlutamine-derived aspartate is required for eIF5A hypusination-mediated translation of HIF-1α to induce the polarization of tumor-associated macrophages
- Dong-Ho Kim
- , Yoo Na Kang
- & Keun-Gyu Park
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| Open AccessGlutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer
- Ji Hye Kim
- , Jinyoung Lee
- & Jaekyoung Son
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Review Article
| Open AccessRegulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
- Yu Jin Lee
- , Kyeong Jin Shin
- & Young Chan Chae
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Review Article
| Open AccessEntosis: the core mechanism and crosstalk with other cell death programs
- Sunghoon Kim
- , Donghyuk Lee
- & Michael Overholtzer
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| Open AccessTranscriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder
- Min Hak Lee
- , Bada Lee
- & Jin Woo Choi
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Review Article
| Open AccessCargo specificity, regulation, and therapeutic potential of cytoplasmic dynein
- Jin-Gyeong Park
- , Hanul Jeon
- & In-Gyun Lee
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| Open AccessCeramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2
- Wei Dong
- , Qing Li
- & Junfei Jin
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Article
| Open AccessAge-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
- Youngbum Yoo
- , MyeongHoon Yeon
- & Young-Kyo Seo
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| Open AccessExperimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
- Martin Hart
- , Fabian Kern
- & Eckart Meese
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| Open AccessInvolvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy
- Jialiang Lin
- , Longjie Wang
- & Weishi Li
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| Open AccessPrmt7 regulates the JAK/STAT/Socs3 signaling pathway in postmenopausal cardiomyopathy
- Byeong-Yun Ahn
- , Yan Zhang
- & Jong-Sun Kang
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| Open AccessThe Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
- Dae Jin Jeong
- , Jee-Hyun Um
- & Jeanho Yun
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| Open AccessSynergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity
- Jihoon G. Yoon
- , Dong Geon Jang
- & Min Goo Lee
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Article
| Open AccessMechanical overload-induced release of extracellular mitochondrial particles from tendon cells leads to inflammation in tendinopathy
- Ziming Chen
- , Mengyuan Li
- & Ming H. Zheng
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Article
| Open AccessAdvanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop
- Sheng Yang
- , JiaJun Xie
- & Yang Zhang
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| Open AccessHelicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer
- Yanmei Peng
- , Xuetao Lei
- & Guoxin Li
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Review Article
| Open AccessDistinct characteristics of the DNA damage response in mammalian oocytes
- Jiyeon Leem
- , Crystal Lee
- & Jeong Su Oh
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| Open AccessNucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway
- Shuo Tian
- , Xuanzuo Chen
- & Yizhong Peng
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| Open AccessThe deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β
- Jiaxing Miao
- , Lian Li
- & Jing Zhao
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Review Article
| Open AccessUnraveling the intricacies of osteoclast differentiation and maturation: insight into novel therapeutic strategies for bone-destructive diseases
- Noriko Takegahara
- , Hyunsoo Kim
- & Yongwon Choi
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Review Article
| Open AccessExploring the potential of Toxoplasma gondii in drug development and as a delivery system
- Chanjin Yoon
- , Yu Seong Ham
- & Chul-Su Yang
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| Open AccessCathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling
- Seul Gi Lee
- , Seon Min Woo
- & Taeg Kyu Kwon
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Review Article
| Open AccessRelevance of the endoplasmic reticulum-mitochondria axis in cancer diagnosis and therapy
- Garam An
- , Junho Park
- & Whasun Lim
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Review Article
| Open AccessMultifaceted roles of CCAR family proteins in the DNA damage response and cancer
- D. Lugano
- , L. Barrett
- & Y. Kee
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Review Article
| Open AccessMitochondria as secretory organelles and therapeutic cargos
- Joonho Suh
- & Yun-Sil Lee
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| Open AccessVitamin D ameliorates age-induced nonalcoholic fatty liver disease by increasing the mitochondrial contact site and cristae organizing system (MICOS) 60 level
- Gyu Hee Kim
- , Hyeon-Ju Jeong
- & Joo Hyun Lim
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Article
| Open AccessWTAP-mediated m6A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis
- Xueying An
- , Rongliang Wang
- & Xingquan Xu
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Review Article
| Open AccessProcessing stimulus dynamics by the NF-κB network in single cells
- Minjun Son
- , Andrew G. Wang
- & Savaş Tay
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Article
| Open AccessDisruption of cholesterol homeostasis triggers periodontal inflammation and alveolar bone loss
- Thanh-Tam Tran
- , Gyuseok Lee
- & Je-Hwang Ryu
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| Open AccessAngiotensin receptor blockers, but not angiotensin-converting enzyme inhibitors, inhibit abnormal bone changes in spondyloarthritis
- Jin Sun Choi
- , Ji-Young Kim
- & Seung Cheol Shim
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| Open AccessIRE1α protects against osteoarthritis by regulating progranulin-dependent XBP1 splicing and collagen homeostasis
- Li Liang
- , Fengmei Zhang
- & Fengjin Guo
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Review Article
| Open AccessLipocalin-2: a therapeutic target to overcome neurodegenerative diseases by regulating reactive astrogliosis
- Byung-Kwon Jung
- & Kwon-Yul Ryu
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Review Article
| Open AccessTargeting E3 ubiquitin ligases and their adaptors as a therapeutic strategy for metabolic diseases
- Yelin Jeong
- , Ah-Reum Oh
- & KyeongJin Kim
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Review Article
| Open AccessA stepwise activation model for the insulin receptor
- Na-Oh Yunn
- , Junhong Kim
- & Yunje Cho
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Review Article
| Open AccessThe stress-responsive protein REDD1 and its pathophysiological functions
- Ji-Yoon Kim
- , Young-Guen Kwon
- & Young-Myeong Kim
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Article
| Open AccessElevated FBXL6 expression in hepatocytes activates VRK2-transketolase-ROS-mTOR-mediated immune evasion and liver cancer metastasis in mice
- Jie Zhang
- , Xiao-Tong Lin
- & Chuan-Ming Xie
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Review Article
| Open AccessPancreatic β-cell mitophagy as an adaptive response to metabolic stress and the underlying mechanism that involves lysosomal Ca2+ release
- Soo-Jin Oh
- , Kihyoun Park
- & Myung-Shik Lee
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Article
| Open AccessThe CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes
- Dan Liu
- , Ruinan Xing
- & Yaling Han
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Review Article
| Open AccessDiversity and complexity of cell death: a historical review
- Wonyoung Park
- , Shibo Wei
- & Ki-Tae Ha
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Review Article
| Open AccessAfter cell death: the molecular machinery of efferocytosis
- Byeongjin Moon
- , Susumin Yang
- & Daeho Park
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Review Article
| Open AccessRegulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis
- Ein Lee
- , Chang-Hyun Song
- & Rajendra Karki
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Review Article
| Open AccessMitochondria-associated programmed cell death as a therapeutic target for age-related disease
- Thanh T. Nguyen
- , Shibo Wei
- & Dongryeol Ryu
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Review Article
| Open AccessAn integrated view of lipid metabolism in ferroptosis revisited via lipidomic analysis
- Jong Woo Kim
- , Ji-Yoon Lee
- & Eun-Woo Lee
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Review Article
| Open AccessPhosphoinositides and intracellular calcium signaling: novel insights into phosphoinositides and calcium coupling as negative regulators of cellular signaling
- Byung-Chul Oh
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- Autophagy
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- Glycobiology
- Mechanisms of disease
- Membrane trafficking
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