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| Open AccessTargeting pyruvate dehydrogenase kinase 1 overcomes EGFR C797S mutation-driven osimertinib resistance in non-small cell lung cancer
- Wonyoung Park
- , Shibo Wei
- & Ki-Tae Ha
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Review Article
| Open AccessRNA-binding proteins and exoribonucleases modulating miRNA in cancer: the enemy within
- Yoona Seo
- , Jiho Rhim
- & Jong Heon Kim
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Article
| Open AccessStress-induced epinephrine promotes hepatocellular carcinoma progression via the USP10-PLAGL2 signaling loop
- Chen Wang
- , Jiaping Ni
- & Weiwei Hu
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Article
| Open AccessGlutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer
- Ji Hye Kim
- , Jinyoung Lee
- & Jaekyoung Son
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Review Article
| Open Access3C methods in cancer research: recent advances and future prospects
- Insoo Yoon
- , Uijin Kim
- & Dong-Sung Lee
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Article
| Open AccessOvercoming BRAF and CDK4/6 inhibitor resistance by inhibiting MAP3K3-dependent protection against YAP lysosomal degradation
- Sanghyun Park
- , Won-Ji Ryu
- & Joon Kim
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Article
| Open AccessCentral neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression
- Yeajina Lee
- , Tamrin Chowdhury
- & Jong-Il Kim
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Review Article
| Open AccessRegulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
- Yu Jin Lee
- , Kyeong Jin Shin
- & Young Chan Chae
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Review Article
| Open AccessEntosis: the core mechanism and crosstalk with other cell death programs
- Sunghoon Kim
- , Donghyuk Lee
- & Michael Overholtzer
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Article
| Open AccessMethyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition
- Niaz Mahmood
- , Ani Arakelian
- & Shafaat A. Rabbani
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Article
| Open AccessExtracellular vesicle-mediated transfer of miRNA-1 from primary tumors represses the growth of distant metastases
- Chae-Yi Kim
- , Kang-Hoon Lee
- & Je-Yoel Cho
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Article
| Open AccessAcetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism
- Kyung Hee Jung
- , Sujin Lee
- & Soon-Sun Hong
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Article
| Open AccessCancer-derived exosomal Alu RNA promotes colorectal cancer progression
- Sara Magliacane Trotta
- , Antonio Adinolfi
- & Valeria Tarallo
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Review Article
| Open AccessRebuilding the microenvironment of primary tumors in humans: a focus on stroma
- Siwon Mun
- , Hyun Jin Lee
- & Pilnam Kim
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Review Article
| Open AccessExtramedullary hematopoiesis in cancer
- Derek A. G. Barisas
- & Kyunghee Choi
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Article
| Open AccessSIRT1 ISGylation accelerates tumor progression by unleashing SIRT1 from the inactive state to promote its deacetylase activity
- Ji An Kang
- , Yoon Jung Kim
- & Young Joo Jeon
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Article
| Open AccessAdvances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability
- Ken Takasawa
- , Ken Asada
- & Ryuji Hamamoto
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Review Article
| Open AccessHypoxia, oxidative stress, and the interplay of HIFs and NRF2 signaling in cancer
- Taegeun Bae
- , Steffanus Pranoto Hallis
- & Mi-Kyoung Kwak
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Article
| Open AccessRNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer
- Xiaoyi Liu
- , Qinglv Wei
- & Ping Yi
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Article
| Open AccessHelicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer
- Yanmei Peng
- , Xuetao Lei
- & Guoxin Li
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Article
| Open AccessCathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling
- Seul Gi Lee
- , Seon Min Woo
- & Taeg Kyu Kwon
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Article
| Open AccessRole of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy
- Hyunho Cha
- , Minwoo Kim
- & Jungwook Hwang
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Article
| Open AccessCYB5R3 functions as a tumor suppressor by inducing ER stress-mediated apoptosis in lung cancer cells via the PERK-ATF4 and IRE1α-JNK pathways
- Joo-Young Im
- , Soo Jin Kim
- & Misun Won
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Article
| Open AccessPRKCSH contributes to TNFSF resistance by extending IGF1R half-life and activation in lung cancer
- Gu-Choul Shin
- , Hyeong Min Lee
- & Kyun-Hwan Kim
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Article
| Open AccessThe polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer
- Ye-Lim Kang
- , Jiyoung Kim
- & Jong-Wan Park
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Review Article
| Open AccessSoluble receptors in cancer: mechanisms, clinical significance, and therapeutic strategies
- Eun-Ji Park
- & Chang-Woo Lee
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Article
| Open AccessElevated expression of WSB2 degrades p53 and activates the IGFBP3-AKT-mTOR-dependent pathway to drive hepatocellular carcinoma
- Xun Li
- , Cheng-Cheng Zhang
- & Chuan-Ming Xie
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Review Article
| Open AccessSignificance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer
- Ji Eun Yu
- , In Jun Yeo
- & Jin Tae Hong
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Review Article
| Open AccessModification of immune cell-derived exosomes for enhanced cancer immunotherapy: current advances and therapeutic applications
- Inseong Jung
- , Sanghee Shin
- & Kyungmoo Yea
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Correspondence
| Open AccessPiezo channels in the urinary system: Correspondence
- Shuaishuai Hu
- & Xudong Yao
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Review Article
| Open AccessTumor-suppressive functions of protein lysine methyltransferases
- Nur Aziz
- , Yo Han Hong
- & Jae Youl Cho
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Article
| Open AccessLactate exacerbates lung damage induced by nanomicroplastic through the gut microbiota–HIF1a/PTBP1 pathway
- Lihui Xuan
- , Zheng Xu
- & Ruixue Huang
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Article
| Open AccessCaveolin-1 mediates the utilization of extracellular proteins for survival in refractory gastric cancer
- Nahee Hwang
- , Bo Kyung Yoon
- & Jae-woo Kim
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Review Article
| Open AccessNormalization of the tumor microenvironment by harnessing vascular and immune modulation to achieve enhanced cancer therapy
- Yechan Choi
- & Keehoon Jung
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Article
| Open AccessCircular RNA cFAM210A, degradable by HBx, inhibits HCC tumorigenesis by suppressing YBX1 transactivation
- Jian Yu
- , Wen Li
- & Fu Yang
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Article
| Open AccessSingle-cell characterization of macrophages in uveal melanoma uncovers transcriptionally heterogeneous subsets conferring poor prognosis and aggressive behavior
- Ke Li
- , Lanfang Sun
- & Meng Zhou
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Article
| Open AccessCancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection
- Su Yeon Kim
- , Seongmun Jeong
- & Tae-You Kim
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Article
| Open AccessOncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer
- Dong Hoon Shin
- , Jeong Yeon Jo
- & Sang Soo Kim
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Article
| Open AccessIntegrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas
- Hidenori Machino
- , Ai Dozen
- & Ryuji Hamamoto
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Review Article
| Open AccessFunctional significance of cholesterol metabolism in cancer: from threat to treatment
- Mingming Xiao
- , Jin Xu
- & Si Shi
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Review Article
| Open AccessDrug conjugates for targeting regulatory T cells in the tumor microenvironment: guided missiles for cancer treatment
- Juwon Yang
- & Hyunsu Bae
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Article
| Open AccessElevated FBXL6 expression in hepatocytes activates VRK2-transketolase-ROS-mTOR-mediated immune evasion and liver cancer metastasis in mice
- Jie Zhang
- , Xiao-Tong Lin
- & Chuan-Ming Xie
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Review Article
| Open AccessMechanistic insights into the dual role of CCAR2/DBC1 in cancer
- Hwa Jin Kim
- , Sue Jin Moon
- & Jeong Hoon Kim
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Article
| Open AccessThe deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis
- Soo Yeon Lee
- , Soo-Yeon Park
- & Ho-Geun Yoon
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Article
| Open AccessSLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways
- Xiaojuan Ren
- , Chao Feng
- & Peng Hou
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Article
| Open AccessAIVariant: a deep learning-based somatic variant detector for highly contaminated tumor samples
- Hyeonseong Jeon
- , Junhak Ahn
- & Daehyun Baek
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Review Article
| Open AccessEmerging roles of tRNA-derived small RNAs in cancer biology
- Saebyeol Lee
- , Jungeun Kim
- & Hak Kyun Kim
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Review Article
| Open AccessMicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies
- Taewan Kim
- & Carlo M. Croce
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Review Article
| Open AccessHistone modifications in drug-resistant cancers: From a cancer stem cell and immune evasion perspective
- Ming Li Jin
- & Kwang Won Jeong
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