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Review Article
| Open AccessParadigm shift required for translational research on the brain
- Jong Hyuk Yoon
- , Dongha Lee
- & Pann-Ghill Suh
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Review Article
| Open AccessAcid sphingomyelinase as a pathological and therapeutic target in neurological disorders: focus on Alzheimer’s disease
- Byung Jo Choi
- , Min Hee Park
- & Jae-sung Bae
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Article
| Open AccessSynaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex
- Jeongseop Kim
- , Sihwan Seol
- & Hyo Jung Kang
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Article
| Open AccessDeficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis
- Do-Wan Shim
- , Jun-Cheol Eo
- & Je-Wook Yu
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Review Article
| Open AccessThe multifaceted functions of β-arrestins and their therapeutic potential in neurodegenerative diseases
- Teresa R. Kee
- , Sophia A. Khan
- & Jung-A A. Woo
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Article
| Open AccessMaintaining Drosha expression with Cdk5 inhibitors as a potential therapeutic strategy for early intervention after TBI
- Lu Huang
- , Li Xia
- & Qian Yang
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Review Article
| Open AccessPathological phenotypes of astrocytes in Alzheimer’s disease
- Junhyung Kim
- , Ik Dong Yoo
- & Jong-Seok Moon
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Review Article
| Open AccessCurrent understanding of the Alzheimer’s disease-associated microbiome and therapeutic strategies
- Dong-oh Seo
- & David M. Holtzman
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Article
| Open AccessSpatiotemporal characterization of glial cell activation in an Alzheimer’s disease model by spatially resolved transcriptomics
- Hongyoon Choi
- , Eun Ji Lee
- & Dong Soo Lee
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Article
| Open AccessPLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III
- Hye Yun Kim
- , Jieun Lee
- & Jae-Ick Kim
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Article
| Open AccessHMGB1 induces hepcidin upregulation in astrocytes and causes an acute iron surge and subsequent ferroptosis in the postischemic brain
- Dashdulam Davaanyam
- , Hahnbi Lee
- & Ja-Kyeong Lee
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Article
| Open AccessKetohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction
- Yansong Li
- , Tao Jiang
- & Qiang Wang
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Review Article
| Open AccessLipocalin-2: a therapeutic target to overcome neurodegenerative diseases by regulating reactive astrogliosis
- Byung-Kwon Jung
- & Kwon-Yul Ryu
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Article
| Open AccessTrametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer’s disease
- Mi-Yeon Kim
- , Mi Jeong Kim
- & Sungho Han
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Article
| Open AccessImpact of the circadian nuclear receptor REV-ERBα in dorsal raphe 5-HT neurons on social interaction behavior, especially social preference
- Sangwon Jang
- , Inah Park
- & Kyungjin Kim
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Review Article
| Open AccessOlfactory modulation of stress-response neural circuits
- Min-Gi Shin
- , Yiseul Bae
- & Eun Jeong Lee
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Article
| Open AccessDysregulation of the Wnt/β-catenin signaling pathway via Rnf146 upregulation in a VPA-induced mouse model of autism spectrum disorder
- Gaeun Park
- , Wooyoung Eric Jang
- & Yong-Seok Lee
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Review Article
| Open AccessOrchestration of synaptic functions by WAVE regulatory complex-mediated actin reorganization
- Kyung Ah Han
- & Jaewon Ko
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Article
| Open AccessActivation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABAA receptor transport in a murine model
- Jing Liu
- , Pingyang Ke
- & Fei Xiao
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Article
| Open AccessSex differences in the progression of glucose metabolism dysfunction in Alzheimer’s disease
- Jong-Chan Park
- , Hanbyeol Lim
- & Inhee Mook-Jung
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Review Article
| Open AccessGlutathionylation on RNA-binding proteins: a regulator of liquid‒liquid phase separation in the pathogenesis of amyotrophic lateral sclerosis
- Hyun-Jun Choi
- , Ji Young Lee
- & Kiyoung Kim
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Article
| Open AccessNLRP3-dependent lipid droplet formation contributes to posthemorrhagic hydrocephalus by increasing the permeability of the blood–cerebrospinal fluid barrier in the choroid plexus
- Zhaoqi Zhang
- , Peiwen Guo
- & Yujie Chen
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Article
| Open AccessVisuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant
- Kwang Wook Min
- , Namsuk Kim
- & Jin Woo Kim
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Article
| Open AccessTRPV1 regulates ApoE4-disrupted intracellular lipid homeostasis and decreases synaptic phagocytosis by microglia
- Chenfei Wang
- , Jia Lu
- & Zhihua Yu
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Article
| Open AccessBiomolecular condensate assembly of nArgBP2 tunes its functionality to manifest the structural plasticity of dendritic spines
- Eunji Cho
- , Sang-Eun Lee
- & Sunghoe Chang
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Article
| Open AccessPhenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin–p65 interaction
- Junhyeong Yim
- , Jaeseok Lee
- & Seung Bum Park
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Review Article
| Open AccessNeurovascular coupling in bone regeneration
- Qizhi Qin
- , Seungyong Lee
- & Aaron W. James
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Article
| Open AccessTransplanting neurofibromatosis-1 gene knockout neural stem cells improve functional recovery in rats with spinal cord injury by enhancing the mTORC2 pathway
- Guoliang Chen
- , Xianlong Li
- & Shaoyu Liu
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Article
| Open AccessAβ-induced mitochondrial dysfunction in neural progenitors controls KDM5A to influence neuronal differentiation
- Dong Kyu Kim
- , Hyobin Jeong
- & Inhee Mook-Jung
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Article
| Open AccessDevelopment of a spontaneous pain indicator based on brain cellular calcium using deep learning
- Heera Yoon
- , Myeong Seong Bak
- & Sun Kwang Kim
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Article
| Open AccessInhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis
- Woojin Won
- , Hyun-Ji Choi
- & C. Justin Lee
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Article
| Open AccessSuppression of exaggerated NMDAR activity by memantine treatment ameliorates neurological and behavioral deficits in aminopeptidase P1-deficient mice
- Young-Soo Bae
- , Sang Ho Yoon
- & Myoung-Hwan Kim
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Article
| Open AccessMeCP2 inhibits ischemic neuronal injury by enhancing methylation of the FOXO3a promoter to repress the SPRY2-ZEB1 axis
- Lei Meng
- , Bin Feng
- & Guangyu Zhao
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Article
| Open AccessLeukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio)
- Xiang-Ke Chen
- , Joseph Shiu-Kwong Kwan
- & Raymond Chuen-Chung Chang
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Review Article
| Open AccessRoles and mechanisms of ankyrin-G in neuropsychiatric disorders
- Sehyoun Yoon
- , Nicolas H. Piguel
- & Peter Penzes
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Article
| Open AccessTNF-α promotes α-synuclein propagation through stimulation of senescence-associated lysosomal exocytosis
- Eun-Jin Bae
- , Minsun Choi
- & Seung-Jae Lee
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Article
| Open AccessSuberoylanilide hydroxamic acid suppresses axonal damage and neurological dysfunction after subarachnoid hemorrhage via the HDAC1/HSP70/TDP-43 axis
- Kui Luo
- , Zhifei Wang
- & Aihua Liu
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Review Article
| Open AccessBrain circuits for promoting homeostatic and non-homeostatic appetites
- Benjamin Hyunju Ahn
- , Minyoo Kim
- & Sung-Yon Kim
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Review Article
| Open AccessMetabolic factors in the regulation of hypothalamic innate immune responses in obesity
- Andrew Folick
- , Rachel T. Cheang
- & Suneil K. Koliwad
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Review Article
| Open AccessRole of the gut–brain axis in energy and glucose metabolism
- Hallie R. Wachsmuth
- , Savanna N. Weninger
- & Frank A. Duca
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Review Article
| Open AccessAutonomic control of energy balance and glucose homeostasis
- Uisu Hyun
- & Jong-Woo Sohn
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Review Article
| Open AccessDoes SARS-CoV-2 affect neurodegenerative disorders? TLR2, a potential receptor for SARS-CoV-2 in the CNS
- Marcell P. Szabo
- , Michiyo Iba
- & Changyoun Kim
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Review Article
| Open AccessHypothalamic control of energy expenditure and thermogenesis
- Le Trung Tran
- , Sohee Park
- & Obin Kwon
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Article
| Open AccessMultimodal evaluation of an interphotoreceptor retinoid-binding protein-induced mouse model of experimental autoimmune uveitis
- Jee Myung Yang
- , KyungA Yun
- & Joo Yong Lee
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Article
| Open AccessTRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury
- Qian Xia
- , Gaofeng Zhan
- & Xing Li
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Article
| Open AccessSenescence and impaired DNA damage responses in alpha-synucleinopathy models
- Ye-Seul Yoon
- , Jueng Soo You
- & He-Jin Lee
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