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Drosophila
In this focus
Nature is delighted to present a special issue on Drosophila biology, genomics and evolution. Papers include reviews on the unique place of the fruit fly in laboratory studies in many fields of biology, and analyses of ten novel Drosophila primary genome sequences. These sequences allowed researchers to examine genes and transcripts on an entire phylogenetic framework simultaneously, and will assist studies in most areas of biology.
Image: Andrew G. Clark/Cornell University
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Current Research
EDITORIAL
Genome labours bear fruit free access
Chris Gunter et al.
Nature 450, 183 (08 November 2007) doi:10.1038/450183a
NEWS
Attack of the genomes
Heidi Ledford
Nature 450, 142–143 (08 November 2007) doi:10.1038/450142a
ARTICLE
Evolution of genes and genomes on the Drosophila phylogeny free access
Drosophila 12 Genomes Consortium
Nature 450, 203–218 (08 November 2007) doi:10.1038/nature06341
Abstract | Full Text | PDF | Supplementary Information
ARTICLE
Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures free access
Alexander Stark et al.
Nature 450, 219–232 (08 November 2007) doi:10.1038/nature06340
Abstract | Full Text | PDF | Supplementary Information
LETTER
Constraint and turnover in sex-biased gene expression in the genus Drosophila free access
Yu Zhang, David Sturgill, Michael Parisi, Sudhir Kumar & Brian Oliver
Nature 450, 233–237 (08 November 2007) doi:10.1038/nature06323
Abstract | Full Text | PDF | Supplementary Information
LETTER
Demasculinization of X chromosome genes in the Drosophila genus free access
David Sturgill, Yu Zhang, Michael Parisi & Brian Oliver.
Nature 450, 238–241 (08 November 2007) doi:10.1038/nature06330
Abstract | Full Text | PDF | Supplementary Information
NEWS AND VIEWS
Come fly with us free access
Ewan Birney
Nature 450, 184–185 (08 November 2007) doi:10.1038/450184a
PROGRESS
Drosophila and the genetics of the internal milieu free access
Pierre Leopold & Norbert Perrimon
Nature 450, 186–188 (08 November 2007) doi:10.1038/nature06286
PROGRESS
Orchestrating size and shape during morphogenesis free access
Thomas Lecuit & Loïc Le Goff
Nature 450, 189–192 (08 November 2007) doi:10.1038/nature06304
REVIEW
Into the mind of a fly free access
Leslie B. Vosshall
Nature 450, 193–197 (08 November 2007) doi:10.1038/nature06335
REVIEW
Imaging Drosophila gene activation and polymerase pausing in vivo free access
John T. Lis
Nature 450, 198–202 (08 November 2007) doi:10.1038/nature06324
ESSAY
Time to pick the fly's brain free access
Claude Desplan
Nature 450, 173 (08 November 2007) doi:10.1038/450173a
Related Research Paper from Nature Genetics
Dynamic evolution of the innate immune system in Drosophila
Timothy B. Sackton et al.
Nature Genetics advanced online publication (07 November 2007) doi:10.1038/ng.2007.60
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Podcast
Listen to our special features on the Drosophila genomes in the Nature Podcast, and hear
the mating sounds of a Brazilian species.
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Links
- Genome Research 12 Drosophila Genomes Special Section
- Related paper from PLoS ONE
- Related papers from PLOS Genetics
- FlyBase
- Assembly/Alignment/Annotation of 12 Related Drosophila Species
- The Interactive Fly
- Berkeley Drosophila Genome Project
- Related Drosophila papers from Molecular Biology and Evolution
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Archive
Genome sequencing
ARTICLE
Initial sequencing and comparative analysis of the mouse genome free access
Mouse Genome Sequencing Consortium
Nature 420, 520–562 (5 December 2002) doi:10.1038/nature01262
Abstract | Full Text | PDF | Supplementary Information
ARTICLE
Genome sequence of the Brown Norway rat yields insights into mammalian evolution free access
Rat Genome Sequencing Project Consortium
Nature 428, 493–521 (1 April 2004) doi:10.1038/nature02426
Abstract | Full Text | PDF | Supplementary Information
Genome annotation
ARTICLE
Systematic discovery of regulatory motifs in human promoters and 3'UTRs by comparison of several mammals
Xiaohui Xie et al.
Nature 434, 338–345 (17 March 2005) doi:10.1038/nature03441
Abstract | Full Text | PDF | Supplementary Information
ARTICLE
Sequencing and comparison of yeast species to identify genes and regulatory elements
Manolis Kellis, Nick Patterson, Matthew Endrizzi, Bruce Birren & Eric S. Lander
Nature 423, 241–254 (15 May 2003) doi:10.1038/nature01644
Abstract | Full Text | PDF | Supplementary Information
LETTER
Natural selection on human microRNA binding sites inferred from SNP data
Kevin Chen & Nikolaus Rajewsky
Nature Genetics 38, 1452–1456 (29 October 2006) doi:10.1038/ng1910
Abstract | Full Text | PDF | Supplementary Information
Drosophila
NEWS AND VIEWS
Developmental biology: A ten per cent solution
John Reinitz
Nature 448, 420–421 (26 July 2007) doi:10.1038/448420a
LETTER
Morphological evolution through multiple cis-regulatory mutations at a single gene
Alistair P. McGregor et al.
Nature 448, 587–590 (2 August 2007) doi:10.1038/nature05988
Abstract | Full Text | PDF | Supplementary Information
ARTICLE
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
Georg Dietzl et al.
Nature 448, 151–156 (12 July 2007) doi:10.1038/nature05954
Abstract | Full Text | PDF | Supplementary Information