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Drosophila

In this focus

Nature is delighted to present a special issue on Drosophila biology, genomics and evolution. Papers include reviews on the unique place of the fruit fly in laboratory studies in many fields of biology, and analyses of ten novel Drosophila primary genome sequences. These sequences allowed researchers to examine genes and transcripts on an entire phylogenetic framework simultaneously, and will assist studies in most areas of biology.

Image: Andrew G. Clark/Cornell University


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Current Research

EDITORIAL

Genome labours bear fruit free access

Chris Gunter et al.

Nature 450, 183 (08 November 2007) doi:10.1038/450183a


NEWS

Attack of the genomes

Heidi Ledford

Nature 450, 142–143 (08 November 2007) doi:10.1038/450142a


ARTICLE

Evolution of genes and genomes on the Drosophila phylogeny free access

Drosophila 12 Genomes Consortium

Nature 450, 203–218 (08 November 2007) doi:10.1038/nature06341


ARTICLE

Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures free access

Alexander Stark et al.

Nature 450, 219–232 (08 November 2007) doi:10.1038/nature06340


LETTER

Constraint and turnover in sex-biased gene expression in the genus Drosophila free access

Yu Zhang, David Sturgill, Michael Parisi, Sudhir Kumar & Brian Oliver

Nature 450, 233–237 (08 November 2007) doi:10.1038/nature06323


LETTER

Demasculinization of X chromosome genes in the Drosophila genus free access

David Sturgill, Yu Zhang, Michael Parisi & Brian Oliver.

Nature 450, 238–241 (08 November 2007) doi:10.1038/nature06330


NEWS AND VIEWS

Come fly with us free access

Ewan Birney

Nature 450, 184–185 (08 November 2007) doi:10.1038/450184a


PROGRESS

Drosophila and the genetics of the internal milieu free access

Pierre Leopold & Norbert Perrimon

Nature 450, 186–188 (08 November 2007) doi:10.1038/nature06286


PROGRESS

Orchestrating size and shape during morphogenesis free access

Thomas Lecuit & Loïc Le Goff

Nature 450, 189–192 (08 November 2007) doi:10.1038/nature06304


REVIEW

Into the mind of a fly free access

Leslie B. Vosshall

Nature 450, 193–197 (08 November 2007) doi:10.1038/nature06335


REVIEW

Imaging Drosophila gene activation and polymerase pausing in vivo free access

John T. Lis

Nature 450, 198–202 (08 November 2007) doi:10.1038/nature06324


ESSAY

Time to pick the fly's brain free access

Claude Desplan

Nature 450, 173 (08 November 2007) doi:10.1038/450173a


Related Research Paper from Nature Genetics

Dynamic evolution of the innate immune system in Drosophila

Timothy B. Sackton et al.

Nature Genetics advanced online publication (07 November 2007) doi:10.1038/ng.2007.60


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Podcast

Listen to our special features on the Drosophila genomes in the Nature Podcast, and hear the mating sounds of a Brazilian species.


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Archive

Genome sequencing

ARTICLE

Initial sequencing and comparative analysis of the mouse genome free access

Mouse Genome Sequencing Consortium

Nature 420, 520–562 (5 December 2002) doi:10.1038/nature01262


ARTICLE

Genome sequence of the Brown Norway rat yields insights into mammalian evolution free access

Rat Genome Sequencing Project Consortium

Nature 428, 493–521 (1 April 2004) doi:10.1038/nature02426



Genome annotation

ARTICLE

Systematic discovery of regulatory motifs in human promoters and 3'UTRs by comparison of several mammals

Xiaohui Xie et al.

Nature 434, 338–345 (17 March 2005) doi:10.1038/nature03441


ARTICLE

Sequencing and comparison of yeast species to identify genes and regulatory elements

Manolis Kellis, Nick Patterson, Matthew Endrizzi, Bruce Birren & Eric S. Lander

Nature 423, 241–254 (15 May 2003) doi:10.1038/nature01644


LETTER

Natural selection on human microRNA binding sites inferred from SNP data

Kevin Chen & Nikolaus Rajewsky

Nature Genetics 38, 1452–1456 (29 October 2006) doi:10.1038/ng1910



Drosophila

NEWS AND VIEWS

Developmental biology: A ten per cent solution

John Reinitz

Nature 448, 420–421 (26 July 2007) doi:10.1038/448420a


LETTER

Morphological evolution through multiple cis-regulatory mutations at a single gene

Alistair P. McGregor et al.

Nature 448, 587–590 (2 August 2007) doi:10.1038/nature05988


ARTICLE

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

Georg Dietzl et al.

Nature 448, 151–156 (12 July 2007) doi:10.1038/nature05954