Supplementary information

From the following article:

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

Rat Genome Sequencing Project Consortium

Nature 428, 493-521(1 April 2004)

doi:10.1038/nature02426

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Supplementary Information

Additional history of the rat, rat genetics, and the rat genome sequencing project.

Supplementary Figure 1

BAC clone selection process.

Supplementary Figure 2

Coverage of finished BACs based on depth of BAC bait coverage.

Supplementary Figure 3

Partitioning of the Fingerprint and YAC map contigs against the rat sequence assembly.

Supplementary Figure 4

Coverage of BAC clones selected for sequencing from the fingerprint map.

Supplementary Figure 5

Correlation of SINE locations in rat and mouse.

Supplementary Figure 6

Dot-plots showing positions of aligning segments in rat-rat, rat-mouse, and rat-human comparisons, for a 10 Mb region of rat Chromosome 10 and the orthologous regions in mouse and human.

Supplementary Figure 7

Sequence conservation at AG acceptor splice sites in aligned introns.

Supplementary Figure 8

Sequence conservation at GT donor splice sites in aligned introns.

Supplementary Tables

Table 1). Mammalian genome sequences categorized by alignments and inferred origins; Table 2). Contigs anchored to chromosomes; Table 3). Mitochondrial genome sequence comparison; Table 4). CpG Island distribution by chromosome; Table 5). Rat non-coding RNAs; Table 6). Gene count in human, mouse and rat genomes; Table 7). Gene predictions on the rat genome.

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