'Homeostasis', from the Greek words for 'same' and 'steady', refers to ways in which the body acts to maintain a stable internal environment despite perturbations. Recent studies in Drosophila exemplify the conservation of regulatory mechanisms involved in metabolic homeostasis. These new findings underscore the use of Drosophila as a model for the study of various human disorders.

1. University of Nice-Sophia Antipolis/CNRS UMR6543, Parc Valrose, 06108 Nice cedex 2, France
2. Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA

Correspondence to: Pierre Leopold¹Norbert Perrimon² Correspondence should be addressed to P.L. (Email: leopold@unice.fr) or N.P. (Email: perrimon@receptor.med.harvard.edu).

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