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News and Views
Nature 448, 420-421 (26 July 2007) | doi:10.1038/448420a; Published online 25 July 2007
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Bioresearch Manager
- Philip Morris International (PMI)
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Senior Scientist, Chemoinformatics
- Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
- Copenhagen 2200 Denmark
Developmental biology: A ten per cent solution
John Reinitz1
Abstract
In early embryos, a concentration gradient of the Bicoid protein affects pattern formation. Studies of living embryos reveal a surprising level of accuracy in the Bicoid gradient. But is it accurate enough?
A central idea in developmental biology is Lewis Wolpert's theory of positional information1. This states that a substance present in a concentration gradient induces different developmental fates in cells when present at different concentrations.
- John Reinitz is in the Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York 11794-3600, USA.
Email: reinitz@odd.bio.sunysb.edu
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