Progress

Nature 450, 189-192 (8 November 2007) | doi:10.1038/nature06304

Orchestrating size and shape during morphogenesis

Thomas Lecuit1,2 & Loïc Le Goff1,2

Living organisms exhibit tremendous diversity, evident in the large repertoire of forms and considerable size range. Scientists have discovered that conserved mechanisms control the development of all organisms. Drosophila has proved to be a particularly powerful model system with which to identify the signalling pathways that organize tissue patterns. More recently, much has been learned about the control of tissue growth, tissue shape and their coordination at the cellular and tissue levels. New models integrate how specific signals and mechanical forces shape tissues and may also control their size.

  1. Université de la Méditerranée, Institut de Biologie du Développement de Marseille Luminy (IBDML),
  2. CNRS, UMR6216, Campus de Luminy case 907, 13288 Marseille Cedex 09, France

Correspondence to: Thomas Lecuit1,2 Correspondence should be addressed to T.L. (Email: lecuit@ibdml.univ-mrs.fr).

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