Featured
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Original Article |
Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis
- K L Jackson
- , R D Dayton
- & R L Klein
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Short Communication |
High cerebrospinal fluid levels of interleukin-10 attained by AAV in dogs
- J Pleticha
- , S A Malkmus
- & A S Beutler
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Original Article |
Delivery of glutamine synthetase gene by baculovirus vectors: a proof of concept for the treatment of acute hyperammonemia
- M A Torres-Vega
- , R Y Vargas-Jerónimo
- & L A Palomares
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Original Article |
Gene therapy approach to FAP: in vivo influence of T119M in TTR deposition in a transgenic V30M mouse model
- A R Batista
- , D Gianni
- & M J Saraiva
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Original Article |
Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy
- D Young
- , D M Fong
- & M J During
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Original Article |
Overexpression of X-Linked Inhibitor of Apoptotic Protein (XIAP) reduces age-related neuronal degeneration in the mouse cochlea
- Q Ruan
- , S Zeng
- & J Wang
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Original Article |
Transduction efficiency of neurons and glial cells by AAV-1, -5, -9, -rh10 and -hu11 serotypes in rat spinal cord following contusion injury
- H A Petrosyan
- , V Alessi
- & V L Arvanian
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Original Article |
CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype
- E R Burnight
- , L A Wiley
- & B A Tucker
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Original Article |
A comparative study of experimental mouse models of central nervous system demyelination
- O M Dumitrascu
- , K R Mott
- & H Ghiasi
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Original Article |
Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain
- B T Harmon
- , A E Aly
- & B L Waszczak
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Original Article |
Herpes simplex virus vector-mediated gene transfer of kynurenine aminotransferase improves detrusor overactivity in spinal cord-injured rats
- C Jia
- , N Yoshimura
- & L Liao
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Original Article |
Long-term correction of biochemical and neurological abnormalities in MLD mice model by neonatal systemic injection of an AAV serotype 9 vector
- N Miyake
- , K Miyake
- & T Shimada
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Short Communication
| Open AccessIntracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats
- T Bucher
- , L Dubreil
- & B Joussemet
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Original Article |
HSV-mediated p55TNFSR reduces neuropathic pain induced by HIV gp120 in rats through CXCR4 activity
- W Huang
- , W Zheng
- & S Hao
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Original Article |
Leptin gene therapy attenuates neuronal damages evoked by amyloid-β and rescues memory deficits in APP/PS1 mice
- R Pérez-González
- , M X Alvira-Botero
- & E Carro
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Enabling Technologies |
Injection parameters and virus dependent choice of promoters to improve neuron targeting in the nonhuman primate brain
- W Lerchner
- , B Corgiat
- & B J Richmond
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Enabling Technologies |
Quantitative morphological comparison of axon-targeting strategies for gene therapies directed to the nigro-striatal projection
- S Padmanabhan
- , T Kareva
- & R E Burke
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Original Article |
MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain
- L Zeng
- , X He
- & G-Y Yang
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Original Article
| Open AccessSustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion
- G Fischer
- , B Pan
- & H Yu
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Original Article |
Adeno-associated virus type 6 is retrogradely transported in the non-human primate brain
- W San Sebastian
- , L Samaranch
- & K S Bankiewicz
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Original Article
| Open AccessEffect of vascular endothelial growth factor gene therapy on post-traumatic peripheral nerve regeneration and denervation-related muscle atrophy
- S Moimas
- , F Novati
- & S Raimondo
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Original Article |
Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates
- S J Gray
- , S Nagabhushan Kalburgi
- & R Jude Samulski
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Original Article |
Comparative effectiveness of antinociceptive gene therapies in animal models of diabetic neuropathic pain
- Y Wang
- , M O Nowicki
- & E A Chiocca
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Original Article |
Venezuelan equine encephalitis virus glycoprotein pseudotyping confers neurotropism to lentiviral vectors
- A Trabalza
- , C Georgiadis
- & N D Mazarakis
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Original Article |
Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord
- H Peluffo
- , E Foster
- & R J Yáñez-Muñoz
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Original Article |
MRI roadmap-guided transendocardial delivery of exon-skipping recombinant adeno-associated virus restores dystrophin expression in a canine model of Duchenne muscular dystrophy
- I M Barbash
- , S Cecchini
- & R M Kotin
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Short Communication
| Open AccessAAV-based shRNA silencing of NF-κB ameliorates muscle pathologies in mdx mice
- Q Yang
- , Y Tang
- & B Wang
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Original Article |
Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer
- L Fjord-Larsen
- , P Kusk
- & L U Wahlberg
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Original Article |
In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression
- A A Rahim
- , A M Wong
- & S N Waddington
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Original Article |
Imaging gene delivery in a mouse model of congenital neuronal ceroid lipofuscinosis
- L S Pike
- , B A Tannous
- & X O Breakefield
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Original Article |
Hepatocyte growth factor incorporated into herpes simplex virus vector accelerates facial nerve regeneration after crush injury
- S Esaki
- , J Kitoh
- & S Murakami
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Short Communication |
Infectious delivery and long-term persistence of transgene expression in the brain by a 135-kb iBAC-FXN genomic DNA expression vector
- A Gimenez-Cassina
- , R Wade-Martins
- & J Diaz-Nido
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Original Article |
The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5
- M S Weinberg
- , B L Blake
- & T J McCown
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Original Article |
Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy
- S Senju
- , M Haruta
- & Y Nishimura
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Original Article |
Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2
- M Zandian
- , K R Mott
- & H Ghiasi
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Original Article |
Lethal toxicity caused by expression of shRNA in the mouse striatum: implications for therapeutic design
- J N Martin
- , N Wolken
- & P Gonzalez-Alegre
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Original Article |
Innocuous full-length botulinum neurotoxin targets and promotes the expression of lentiviral vectors in central and autonomic neurons
- V B O'Leary
- , S V Ovsepian
- & J O Dolly
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Original Article |
Schwann cell targeting via intrasciatic injection of AAV8 as gene therapy strategy for peripheral nerve regeneration
- J Homs
- , L Ariza
- & A Bosch
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Original Article |
Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9
- A Van der Perren
- , J Toelen
- & V Baekelandt
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Original Article |
Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear
- L A Kilpatrick
- , Q Li
- & H Lang
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Original Article |
Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon
- E G Duysen
- , K Parikh
- & N Chilukuri
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Review |
Progress and prospects: stem cells and neurological diseases
- S Gögel
- , M Gubernator
- & S L Minger
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Review |
Progress and prospects: Immunobiology of gene therapy for neurodegenerative disease: prospects and risks
- M M McMenamin
- & M J A Wood
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