Article
|
Open Access
Featured
-
-
Article
| Open AccessMETTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity
- Bernice Woon Li Lee
- , You Heng Chuah
- & Derrick Sek Tong Ong
-
Article
| Open AccessHAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice
- Laiqiang Chen
- , Yiyang Qin
- & Su Yang
-
Article
| Open AccessRAD18 O-GlcNAcylation promotes translesion DNA synthesis and homologous recombination repair
- Xiaolu Ma
- , Hui Fu
- & Caixia Guo
-
Review Article
| Open AccessThe role of circular RNAs in regulating resistance to cancer immunotherapy: mechanisms and implications
- Yu Ma
- , Ting Wang
- & Fangyi Long
-
Article
| Open AccessSprouty1 is a broad mediator of cellular senescence
- Carlos Anerillas
- , Aida Perramon-Güell
- & Mario Encinas
-
Review Article
| Open AccessThe relationship between the network of non-coding RNAs-molecular targets and N6-methyladenosine modification in tumors of urinary system
- Ruiming Li
- , Chunming Zhu
- & Kefeng Wang
-
Article
| Open AccessIdentification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines
- Nahide Yildirim
- , Lakshmi Sarojam
- & Meike Vogler
-
Article
| Open AccessFBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation
- Ya Li
- , Caojian Zuo
- & Lidong Cai
-
Review Article
| Open AccessResearch progress of post-acute sequelae after SARS-CoV-2 infection
- Taiwei Jiao
- , Yuling Huang
- & Lina Yang
-
Article
| Open AccessFOXP3 promote the progression of glioblastoma via inhibiting ferroptosis mediated by linc00857/miR-1290/GPX4 axis
- Wenpeng Cao
- , Ya He
- & Shan Lei
-
Article
| Open AccessLncRNA SNHG26 promotes gastric cancer progression and metastasis by inducing c-Myc protein translation and an energy metabolism positive feedback loop
- Zhen-Hua Wu
- , Yi-Xuan Wang
- & Wei-Jian Guo
-
Article
| Open AccessNuclear receptor NURR1 functions to promote stemness and epithelial-mesenchymal transition in prostate cancer via its targeting of Wnt/β-catenin signaling pathway
- Xingxing Zhang
- , Haolong Li
- & Franky Leung Chan
-
Article
| Open AccessMETTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway
- Lan Ma
- , Xi Zhou
- & Yongchu Pan
-
Article
| Open AccessCasein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells
- V. E. Hermosilla
- , L. Gyenis
- & R. Pincheira
-
Article
| Open AccessSelective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo
- Zhaohua Cai
- , Shaojin You
- & Ming-Hui Zou
-
Article
| Open AccessTAB182 regulates glycolytic metabolism by controlling LDHA transcription to impact tumor radiosensitivity
- Shi Chen
- , Da-Fei Xie
- & Ping-Kun Zhou
-
Article
| Open AccessThe MITF/mir-579-3p regulatory axis dictates BRAF-mutated melanoma cell fate in response to MAPK inhibitors
- Domenico Liguoro
- , Rachele Frigerio
- & Luigi Fattore
-
Review Article
| Open AccessCellular heterogeneity in TNF/TNFR1 signalling: live cell imaging of cell fate decisions in single cells
- Marcus K. Preedy
- , Michael R. H. White
- & Vinay Tergaonkar
-
Article
| Open AccessThe pancancer overexpressed NFYC Antisense 1 controls cell cycle mitotic progression through in cis and in trans modes of action
- Cecilia Pandini
- , Giulia Pagani
- & Paolo Gandellini
-
Article
| Open AccessThe m6A reader IGF2BP2 regulates glycolytic metabolism and mediates histone lactylation to enhance hepatic stellate cell activation and liver fibrosis
- Yongqiang Zhou
- , Jiexi Yan
- & Xun Li
-
Article
| Open AccessCaspase-2 protects against ferroptotic cell death
- Swati Dawar
- , Mariana C. Benitez
- & Nicholas J. Clemons
-
Article
| Open AccessDepletion of the N6-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4
- Limei Deng
- , Yunbo Di
- & Qingyu Zhang
-
Review Article
| Open AccessmTOR pathway occupies a central role in the emergence of latent cancer cells
- Kseniia V. Aleksandrova
- , Mikhail L. Vorobev
- & Irina I. Suvorova
-
Article
| Open AccessPRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis
- Hao Liu
- , Xintian Chen
- & Xiangyang Yu
-
Article
| Open AccessCHOP-mediated Gasdermin E expression promotes pyroptosis, inflammation, and mitochondrial damage in renal ischemia-reperfusion injury
- Nannan Ma
- , Hao Lu
- & Tao Zhang
-
Article
| Open AccessTranscription of endogenous retroviruses in senescent cells contributes to the accumulation of double-stranded RNAs that trigger an anti-viral response that reinforces senescence
- Eros Di Giorgio
- , Liliana Ranzino
- & Claudio Brancolini
-
Article
| Open AccessHRD1-induced TMEM2 ubiquitination promotes ER stress-mediated apoptosis through a non-canonical pathway in intestinal ischemia/reperfusion
- Xuzi Zhao
- , Deshun Liu
- & Xiaofeng Tian
-
Article
| Open AccessInnate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors
- Layla Shojaie
- , Jacob M. Bogdanov
- & Lily Dara
-
Article
| Open AccessHNF4α ubiquitination mediated by Peli1 impairs FAO and accelerates pressure overload-induced myocardial hypertrophy
- Yuxing Hou
- , Pengxi Shi
- & Jiantao Li
-
Article
| Open AccessID4-dependent secretion of VEGFA enhances the invasion capability of breast cancer cells and activates YAP/TAZ via integrin β3-VEGFR2 interaction
- Anna Benedetti
- , Chiara Turco
- & Giulia Fontemaggi
-
Article
| Open AccessIL-17 promotes osteoclast-induced bone loss by regulating glutamine-dependent energy metabolism
- Renpeng Peng
- , Yimin Dong
- & Feng Li
-
Article
| Open AccessCYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma
- Yueshuo Li
- , Chenxing Yang
- & Ya Cao
-
Article
| Open AccessMDM2 provides TOP2 poison resistance by promoting proteolysis of TOP2βcc in a p53-independent manner
- Jianfeng Shu
- , Jinni Jiang
- & Ting Cai
-
Article
| Open AccessDNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1
- Siyu Chen
- , Wenxiang Zhang
- & Chang Liu
-
Review Article
| Open AccessThe multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications
- Faiz Ali Khan
- , Na Fang
- & Shaoping Ji
-
Article
| Open AccessTranscription factor Sp1 transcriptionally enhances GSDME expression for pyroptosis
- Jiasong Pan
- , Yuanyuan Li
- & Jixi Li
-
Article
| Open AccessMETTL3 facilitates renal cell carcinoma progression by PLOD2 m6A-methylation under prolonged hypoxia
- Yimeng Chen
- , Yichen He
- & Dong Xue
-
Article
| Open AccessMETTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner
- Fei Cao
- , Guojun Chen
- & Jingdun Xie
-
Article
| Open AccessUSP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer
- Mingxing Li
- , Jingtian Yu
- & Xinghuan Wang
-
Article
| Open AccessActivated hepatic stellate cell-derived Bmp-1 induces liver fibrosis via mediating hepatocyte epithelial-mesenchymal transition
- Sizhe Wan
- , Xianzhi Liu
- & Bin Wu
-
Article
| Open AccessEpigenetic addition of m5C to HBV transcripts promotes viral replication and evasion of innate antiviral responses
- Shuang Ding
- , Haibin Liu
- & Wuxiang Guan
-
Article
| Open AccessFBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation
- Kai Chen
- , Yue Wang
- & Jia Ma
-
Review Article
| Open AccessMechanisms of immune checkpoint inhibitors: insights into the regulation of circular RNAS involved in cancer hallmarks
- Lingjiao Meng
- , Haotian Wu
- & Lihua Liu
-
Article
| Open AccessLncRNA ZNF674-AS1 drives cell growth and inhibits cisplatin-induced pyroptosis via up-regulating CA9 in neuroblastoma
- Kunming Zhao
- , Xinyi Wang
- & Dianke Yu
-
Review Article
| Open AccessWWP1 E3 ligase at the crossroads of health and disease
- Abhayananda Behera
- & Aramati Bindu Madhava Reddy
-
Article
| Open AccessTRIM21-mediated Sohlh2 ubiquitination suppresses M2 macrophage polarization and progression of triple-negative breast cancer
- Ruihong Zhang
- , Ying Shen
- & Jing Hao
-
Article
| Open AccessGss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice
- Haixia Zhu
- , Yin Cheng
- & Bin Wu
-
Article
| Open AccessMutual communication between radiosensitive and radioresistant esophageal cancer cells modulates their radiosensitivity
- Congying Xie
- , Xiao Chen
- & Kai-Fu Tang
-
Article
| Open AccessImatinib induces ferroptosis in gastrointestinal stromal tumors by promoting STUB1-mediated GPX4 ubiquitination
- Xiangfei Sun
- , Qiang Zhang
- & Kuntang Shen
Browse broader subjects
Browse narrower subjects
- Cell division
- Chromatin
- Chromosomes
- CRISPR-Cas systems
- DNA damage and repair
- DNA metabolism
- DNA recombination
- DNA replication
- Epigenetics
- Non-coding RNAs
- Nuclear organization
- Post-translational modifications
- Protein folding
- Proteolysis
- Proteomics
- Riboswitches
- Ribozymes
- RNA metabolism
- RNAi
- Single-molecule biophysics
- Transcription
- Transcriptomics
- Translation
- Transposition