Post-translational modifications articles within Cell Death & Disease

Featured

• Article
  03 June 2024 | Open Access

  O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts

  • Ninon Very
  • , Clémence Boulet
  •  & Jérôme Eeckhoute

• Article
  24 May 2024 | Open Access

  YOD1 protects against MRSA sepsis-induced DIC through Lys33-linked deubiquitination of NLRP3

  • Chang Liu
  • , Caihong Fan
  •  & Yanna Shen

• Article
  22 May 2024 | Open Access

  TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3

  • Qi Zhang
  • , Yong Li
  •  & Xuan Huang

• Article
  13 May 2024 | Open Access

  Pirh2 modulates the mitochondrial function and cytochrome c-mediated neuronal death during Alzheimer’s disease

  • Abhishek Singh
  • , Shubhangini Tiwari
  •  & Sarika Singh

• Article
  08 May 2024 | Open Access

  RAD18 O-GlcNAcylation promotes translesion DNA synthesis and homologous recombination repair

  • Xiaolu Ma
  • , Hui Fu
  •  & Caixia Guo

• Article
  26 April 2024 | Open Access

  ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7

  • Mengmeng Zhang
  • , Fenglin Cai
  •  & Jingyu Deng

• Article
  13 April 2024 | Open Access

  FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation

  • Ya Li
  • , Caojian Zuo
  •  & Lidong Cai

• Article
  05 March 2024 | Open Access

  The m⁶A reader IGF2BP2 regulates glycolytic metabolism and mediates histone lactylation to enhance hepatic stellate cell activation and liver fibrosis

  • Yongqiang Zhou
  • , Jiexi Yan
  •  & Xun Li

• Article
  02 March 2024 | Open Access

  ISGylation of DRP1 closely balances other post-translational modifications to mediate mitochondrial fission

  • Palamou Das
  •  & Oishee Chakrabarti

• Article
  01 March 2024 | Open Access

  Depletion of the N⁶-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4

  • Limei Deng
  • , Yunbo Di
  •  & Qingyu Zhang

• Article
  27 February 2024 | Open Access

  KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC

  • Jinghan Li
  • , Daiwang Shi
  •  & Hong-Xu Liu

• Article
  24 February 2024 | Open Access

  PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis

  • Hao Liu
  • , Xintian Chen
  •  & Xiangyang Yu

• Article
  20 January 2024 | Open Access

  The LKB1–TSSK1B axis controls YAP phosphorylation to regulate the Hippo–YAP pathway

  • Cho-Long Kim
  • , Su-Bin Lim
  •  & Jung-Soon Mo

• Review Article
  18 January 2024 | Open Access

  The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications

  • Faiz Ali Khan
  • , Na Fang
  •  & Shaoping Ji

• Article
  17 January 2024 | Open Access

  METTL3 facilitates renal cell carcinoma progression by PLOD2 m⁶A-methylation under prolonged hypoxia

  • Yimeng Chen
  • , Yichen He
  •  & Dong Xue

• Article
  13 January 2024 | Open Access

  USP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer

  • Mingxing Li
  • , Jingtian Yu
  •  & Xinghuan Wang

• Article
  12 January 2024 | Open Access

  The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect TRAIL-mediated apoptosis

  • James Holloway
  • , Aidan Seeley
  •  & Emma Evergren

• Article
  12 January 2024 | Open Access

  FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation

  • Kai Chen
  • , Yue Wang
  •  & Jia Ma

• Article
  05 January 2024 | Open Access

  CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression

  • Yujun Shuai
  • , Hui Zhang
  •  & Guosong Jiang

• Review Article
  21 December 2023 | Open Access

  WWP1 E3 ligase at the crossroads of health and disease

  • Abhayananda Behera
  •  & Aramati Bindu Madhava Reddy

• Article
  18 December 2023 | Open Access

  Imatinib induces ferroptosis in gastrointestinal stromal tumors by promoting STUB1-mediated GPX4 ubiquitination

  • Xiangfei Sun
  • , Qiang Zhang
  •  & Kuntang Shen

• Article
  13 December 2023 | Open Access

  The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage

  • Wenwen Cheng
  • , Cifeng Cai
  •  & Zhiyong Liao

• Article
  01 December 2023 | Open Access

  Mitochondrial E3 ligase MARCH5 is a safeguard against DNA-PKcs-mediated immune signaling in mitochondria-damaged cells

  • June Heo
  • , Yeon-Ji Park
  •  & Hyeseong Cho

• Article
  27 November 2023 | Open Access

  Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation

  • Myung Sup Kim
  • , Jung-Hwan Baek
  •  & Kyung-Hee Chun

• Article
  15 November 2023 | Open Access

  BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury

  • Wen Zhang
  • , Kai Liu
  •  & Rong-Hua Yin

• Article
  13 November 2023 | Open Access

  UBE4B interacts with the ITCH E3 ubiquitin ligase to induce Ku70 and c-FLIPL polyubiquitination and enhanced neuroblastoma apoptosis

  • Christophe Le Clorennec
  • , Divya Subramonian
  •  & Peter E. Zage

• Article
  13 November 2023 | Open Access

  Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption

  • Jin-Gang Yang
  • , Bao Sun
  •  & Wei Wang

• Article
  11 October 2023 | Open Access

  PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target

  • Shaifali Singh
  • , Nai Yang Yeat
  •  & Ruey-Hwa Chen

• Article
  11 October 2023 | Open Access

  USP1 promotes cholangiocarcinoma progression by deubiquitinating PARP1 to prevent its proteasomal degradation

  • Deng Yong Zhang
  • , Yan Zhu
  •  & Zheng Lu

• Article
  10 October 2023 | Open Access

  Downregulation of EphA2 stability by RNF5 limits its tumor-suppressive function in HER2-negative breast cancers

  • Xiaojuan Li
  • , Fan Wang
  •  & Ersheng Kuang

• Article
  30 September 2023 | Open Access

  SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells

  • Shu Yang
  • , Guangyan Yang
  •  & Zhen Liang

• Article
  22 September 2023 | Open Access

  FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis

  • Ganesh Kumar Barik
  • , Osheen Sahay
  •  & Manas Kumar Santra

• Article
  19 September 2023 | Open Access

  CSE reduces OTUD4 triggering lung epithelial cell apoptosis via PAI-1 degradation

  • Lijuan Luo
  • , Tiao Li
  •  & Yan Chen

• Article
  12 September 2023 | Open Access

  E2 enzyme Bruce negatively regulates Hippo signaling through POSH-mediated expanded degradation

  • Sha Song
  •  & Xianjue Ma

• Article
  02 September 2023 | Open Access

  Ufmylation on UFBP1 alleviates non-alcoholic fatty liver disease by modulating hepatic endoplasmic reticulum stress

  • Ziming Mao
  • , Xiaowen Ma
  •  & Fengling Chen

• Article
  30 August 2023 | Open Access

  Peptidylarginine deiminase 2 plays a key role in osteogenesis by enhancing RUNX2 stability through citrullination

  • Hyun-Jung Kim
  • , Hye-Rim Shin
  •  & Hyun-Mo Ryoo

• Article
  26 August 2023 | Open Access

  USP14 governs CYP2E1 to promote nonalcoholic fatty liver disease through deubiquitination and stabilization of HSP90AA1

  • Dongqin Wei
  • , Xin Tian
  •  & Chao Sun

• Article
  25 August 2023 | Open Access

  LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion

  • Taiki Abe
  • , Shin-ichiro Kanno
  •  & Yoko Aoki

• Article
  23 August 2023 | Open Access

  N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer

  • Rebecca Yun
  • , Eunji Hong
  •  & Jin Muk Kang

• Article
  09 August 2023 | Open Access

  PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6

  • Yachun Jia
  • , Xiao Yu
  •  & Guangyao Kong

• Article
  03 August 2023 | Open Access

  FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer

  • Mengmeng Wang
  • , Zhoudong Zhang
  •  & Weipeng Wang

• Article
  25 July 2023 | Open Access

  A GSTP1-mediated lactic acid signaling promotes tumorigenesis through the PPP oxidative branch

  • Yandi Sun
  • , Qian He
  •  & Yan Luo

• Article
  21 July 2023 | Open Access

  PDHA1 hyperacetylation-mediated lactate overproduction promotes sepsis-induced acute kidney injury via Fis1 lactylation

  • Sheng An
  • , Yi Yao
  •  & Zhenhua Zeng

• Article
  08 July 2023 | Open Access

  UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

  • Kanghua Xiao
  • , Shengmeng Peng
  •  & Tianxin Lin

• Article
  07 July 2023 | Open Access

  Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids

  • Ayan Chanda
  • , Anusi Sarkar
  •  & Shirin Bonni

• Article
  06 July 2023 | Open Access

  USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1

  • Junyi Duan
  • , Daoyuan Huang
  •  & Genze Shao

• Article
  27 June 2023 | Open Access

  Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer

  • Yonghui Zhang
  • , Tongde Du
  •  & Peiyu Li

• Article
  24 May 2023 | Open Access

  The HOXD9-mediated PAXIP1-AS1 regulates gastric cancer progression through PABPC1/PAK1 modulation

  • Jiaying Li
  • , Miaomiao Pei
  •  & Jide Wang

• Article
  16 May 2023 | Open Access

  HUNK inhibits epithelial-mesenchymal transition of CRC via direct phosphorylation of GEF-H1 and activating RhoA/LIMK-1/CFL-1

  • Xiaoqi Han
  • , Siyuan Jiang
  •  & Shan Gao

• Article
  12 May 2023 | Open Access

  PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression

  • Zhongwei Li
  • , Chaozhen Chen
  •  & Hailong Li