Featured
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| Open AccessThe cell cycle regulator p16 promotes tumor infiltrated CD8+ T cell exhaustion and apoptosis
- Xin Zhang
- , Jiajia Wang
- & Kaili Ma
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Article
| Open AccessResolvin E1 improves efferocytosis and rescues severe aplastic anemia in mice
- Rachel Grazda
- , Allison N. Seyfried
- & Katherine C. MacNamara
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Article
| Open AccessStudy of the potential role of CASPASE-10 mutations in the development of autoimmune lymphoproliferative syndrome
- Filippo Consonni
- , Solange Moreno
- & Aude Magerus
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Article
| Open AccessMacrophage depletion overcomes human hematopoietic cell engraftment failure in zebrafish embryo
- Reine El Omar
- , Naoill Abdellaoui
- & Manuela Tavian
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Article
| Open AccessArsenic trioxide augments immunogenic cell death and induces cGAS-STING-IFN pathway activation in hepatocellular carcinoma
- Xin Li
- , Yu-Fei Pan
- & Xu-Ying Wan
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Article
| Open AccessThe role of CXCL2-mediated crosstalk between tumor cells and macrophages in Fusobacterium nucleatum-promoted oral squamous cell carcinoma progression
- Fujiao Nie
- , Jie Zhang
- & Chengzhe Yang
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Article
| Open AccessSTING agonist diABZI enhances the cytotoxicity of T cell towards cancer cells
- Ling Wang
- , Zhaoduan Liang
- & Yirong Sun
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Review Article
| Open AccessDietary factors and their influence on immunotherapy strategies in oncology: a comprehensive review
- Aleksandra Golonko
- , Tomasz Pienkowski
- & Wlodzimierz Lewandowski
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Review Article
| Open AccessAdvances in Engineered Macrophages: A New Frontier in Cancer Immunotherapy
- Shuaixi Yang
- , Yuhang Wang
- & Junhong Hu
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Article
| Open AccessSTING contributes to lipopolysaccharide-induced tubular cell inflammation and pyroptosis by activating endoplasmic reticulum stress in acute kidney injury
- Yun Cao
- , Xinghua Chen
- & Zhaowei Chen
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Article
| Open AccessSTING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection
- Manish Chauhan
- , Chelsea A. Osbron
- & Alan G. Goodman
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Article
| Open AccessCystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells
- Chenfeng Han
- , Minmin Ge
- & Lianjun Zhang
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Article
| Open AccessLoss of macrophage TSC1 exacerbates sterile inflammatory liver injury through inhibiting the AKT/MST1/NRF2 signaling pathway
- Ming Ni
- , Jiannan Qiu
- & Qiang Zhu
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Article
| Open AccessBlockade of C5aR1 resets M1 via gut microbiota-mediated PFKM stabilization in a TLR5-dependent manner
- Jie Zhao
- , Chen Yao
- & Jing Yang
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Article
| Open AccessCrosstalk of HDAC4, PP1, and GSDMD in controlling pyroptosis
- Weilv Xu
- , Qiao Jin
- & Fushan Shi
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Article
| Open AccessDecoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition
- Melisa J. Montalvo
- , Irfan N. Bandey
- & Navin Varadarajan
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Article
| Open AccessNecroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo
- Stefanie M. Bader
- , James P. Cooney
- & Marcel Doerflinger
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Article
| Open AccessNeutralizing IL-16 enhances the efficacy of targeting Aurora-A therapy in colorectal cancer with high lymphocyte infiltration through restoring anti-tumor immunity
- Shiang-Jie Yang
- , Sheng-Tsung Chang
- & Liang-Yi Hung
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Article
| Open AccessHECTD3 inhibits NLRP3 inflammasome assembly and activation by blocking NLRP3-NEK7 interaction
- Zhuo Cheng
- , Maobo Huang
- & Ceshi Chen
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Article
| Open AccessGlucocorticoid activates STAT3 and NF-κB synergistically with inflammatory cytokines to enhance the anti-inflammatory factor TSG6 expression in mesenchymal stem/stromal cells
- Peiqing Huang
- , Rongrong Sun
- & Yufang Shi
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Article
| Open AccessMETTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner
- Fei Cao
- , Guojun Chen
- & Jingdun Xie
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Article
| Open AccessCharacterizing influence of rCHOP treatment on diffuse large B-cell lymphoma microenvironment through in vitro microfluidic spheroid model
- Matthew R. Sullivan
- , Rachel P. White
- & Tania Konry
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Review Article
| Open AccessAnti-CTLA-4 nanobody as a promising approach in cancer immunotherapy
- Mehregan Babamohamadi
- , Nastaran Mohammadi
- & Jamshid Hadjati
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Article
| Open AccessVaricella zoster virus glycoprotein E facilitates PINK1/Parkin-mediated mitophagy to evade STING and MAVS-mediated antiviral innate immunity
- Soo-Jin Oh
- , Je-Wook Yu
- & Ok Sarah Shin
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Article
| Open AccessEffects of methionine deficiency on B7H3-DAP12-CAR-T cells in the treatment of lung squamous cell carcinoma
- Tao Yu
- , Feng-Qi Nie
- & Ming Sun
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Article
| Open AccessTargeting NEDD8 suppresses surgical stress-facilitated metastasis of colon cancer via restraining regulatory T cells
- Yi Jiang
- , Shenjia Gao
- & Wankun Chen
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Article
| Open AccessAirway epithelial cGAS inhibits LPS-induced acute lung injury through CREB signaling
- Zhangchu Jin
- , Zhehua Shao
- & Fugui Yan
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Article
| Open AccessDifferential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation
- Valentina Casella
- , Eva Domenjo-Vila
- & Andreas Meyerhans
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Article
| Open Accessm6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation
- Baoxiang Chen
- , Yuntian Hong
- & Congqing Jiang
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Article
| Open AccessCancer CD39 drives metabolic adaption and mal-differentiation of CD4+ T cells in patients with non-small-cell lung cancer
- Ying Wang
- , Mengdi Liu
- & Zhenke Wen
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Article
| Open AccessCarboxypeptidase A4 negatively regulates HGS-ETR1/2-induced pyroptosis by forming a positive feedback loop with the AKT signalling pathway
- Luoling Wang
- , Rilin Deng
- & Haizhen Zhu
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Article
| Open AccessMitochondrial E3 ligase MARCH5 is a safeguard against DNA-PKcs-mediated immune signaling in mitochondria-damaged cells
- June Heo
- , Yeon-Ji Park
- & Hyeseong Cho
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Article
| Open AccessInvestigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface
- Jun Liu
- , Yan Deng
- & Jing Yang
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Article
| Open AccessInhibition of SF3B1 improves the immune microenvironment through pyroptosis and synergizes with αPDL1 in ovarian cancer
- Shourong Wang
- , Yao Liu
- & Kun Song
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Article
| Open AccessCaspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide
- Marta Cristaldi
- , Marco Buscetta
- & Chiara Cipollina
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Article
| Open AccessSIRT1 regulates hepatocyte programmed cell death via GSDME - IL18 axis in human and mouse liver transplantation
- Kentaro Kadono
- , Hidenobu Kojima
- & Jerzy W. Kupiec-Weglinski
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Article
| Open AccessNINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis
- Yves Dondelinger
- , Dario Priem
- & Mathieu J. M. Bertrand
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Article
| Open AccessBRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury
- Wen Zhang
- , Kai Liu
- & Rong-Hua Yin
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Article
| Open AccessUbc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation
- Jing Zhang
- , Longmin Chen
- & Cong-Yi Wang
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Article
| Open AccessGasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection
- Sarah Rosli
- , Christopher M. Harpur
- & Michelle D. Tate
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Article
| Open AccessLoss of adenosine A3 receptors accelerates skeletal muscle regeneration in mice following cardiotoxin-induced injury
- Nastaran Tarban
- , Albert Bálint Papp
- & Zsuzsa Szondy
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Article
| Open AccessTargeting cancer-associated adipocyte-derived CXCL8 inhibits triple-negative breast cancer progression and enhances the efficacy of anti-PD-1 immunotherapy
- Renhong Huang
- , Zheng Wang
- & Kunwei Shen
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Article
| Open AccessSirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis
- Yanna Liu
- , Huning Cui
- & Changju Zhu
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Article
| Open AccessmiR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication
- Teresa Fuertes
- , Emigdio Álvarez-Corrales
- & Virginia G. de Yébenes
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Article
| Open AccessCritical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease
- Wenyan Hao
- , Hongxian Zhang
- & Yuxin Yin
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Article
| Open AccessMacrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis
- Qiong Wu
- , Zongwen Liang
- & Yingying Cao
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Article
| Open AccessPolyphenol-rich diet mediates interplay between macrophage-neutrophil and gut microbiota to alleviate intestinal inflammation
- Dandan Han
- , Yujun Wu
- & Junjun Wang
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Article
| Open AccessInflammasome activation occurs in CD4+ and CD8+ T cells during graft-versus-host disease
- Sarah Talley
- , David J. Rademacher
- & Edward M. Campbell
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Article
| Open AccessDepletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte
- Zhiqin Fang
- , Yutong Wang
- & Mingzhu Yin
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