Cell death and immune response articles within Cell Death & Disease

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• Article
  07 June 2024 | Open Access

  TREM2 deficiency aggravates renal injury by promoting macrophage apoptosis and polarization via the JAK-STAT pathway in mice

  • Yan Cui
  • , Chao Chen
  •  & Helong Dai

• Article
  04 May 2024 | Open Access

  Study of the potential role of CASPASE-10 mutations in the development of autoimmune lymphoproliferative syndrome

  • Filippo Consonni
  • , Solange Moreno
  •  & Aude Magerus

• Article
  29 April 2024 | Open Access

  Arsenic trioxide augments immunogenic cell death and induces cGAS-STING-IFN pathway activation in hepatocellular carcinoma

  • Xin Li
  • , Yu-Fei Pan
  •  & Xu-Ying Wan

• Article
  08 March 2024 | Open Access

  STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection

  • Manish Chauhan
  • , Chelsea A. Osbron
  •  & Alan G. Goodman

• Article
  07 February 2024 | Open Access

  Crosstalk of HDAC4, PP1, and GSDMD in controlling pyroptosis

  • Weilv Xu
  • , Qiao Jin
  •  & Fushan Shi

• Article
  02 February 2024 | Open Access

  Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition

  • Melisa J. Montalvo
  • , Irfan N. Bandey
  •  & Navin Varadarajan

• Article
  24 January 2024 | Open Access

  HECTD3 inhibits NLRP3 inflammasome assembly and activation by blocking NLRP3-NEK7 interaction

  • Zhuo Cheng
  • , Maobo Huang
  •  & Ceshi Chen

• Article
  09 January 2024 | Open Access

  Characterizing influence of rCHOP treatment on diffuse large B-cell lymphoma microenvironment through in vitro microfluidic spheroid model

  • Matthew R. Sullivan
  • , Rachel P. White
  •  & Tania Konry

• Article
  05 January 2024 | Open Access

  Targeting NEDD8 suppresses surgical stress-facilitated metastasis of colon cancer via restraining regulatory T cells

  • Yi Jiang
  • , Shenjia Gao
  •  & Wankun Chen

• Article
  18 December 2023 | Open Access

  Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation

  • Valentina Casella
  • , Eva Domenjo-Vila
  •  & Andreas Meyerhans

• Article
  04 December 2023 | Open Access

  Carboxypeptidase A4 negatively regulates HGS-ETR1/2-induced pyroptosis by forming a positive feedback loop with the AKT signalling pathway

  • Luoling Wang
  • , Rilin Deng
  •  & Haizhen Zhu

• Article
  28 November 2023 | Open Access

  Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface

  • Jun Liu
  • , Yan Deng
  •  & Jing Yang

• Article
  25 November 2023 | Open Access

  Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide

  • Marta Cristaldi
  • , Marco Buscetta
  •  & Chiara Cipollina

• Article
  13 October 2023 | Open Access

  Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease

  • Wenyan Hao
  • , Hongxian Zhang
  •  & Yuxin Yin

• Article
  11 October 2023 | Open Access

  Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis

  • Qiong Wu
  • , Zongwen Liang
  •  & Yingying Cao

• Article
  19 August 2023 | Open Access

  OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

  • Lien Verboom
  • , Christopher J. Anderson
  •  & Geert van Loo

• Article
  29 July 2023 | Open Access

  The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2

  • Kunjan Harit
  • , Rituparna Bhattacharjee
  •  & Gopala Nishanth

• Perspective
  20 July 2023 | Open Access

  Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy

  • Carolina Cattoni Koh
  • , Kenneth J. Gollob
  •  & Walderez O. Dutra

• Article
  15 July 2023 | Open Access

  PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation

  • Juan Du
  • , Yahui Liu
  •  & Xiao Su

• Article
  14 July 2023 | Open Access

  Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling

  • Emily R. Quarato
  • , Noah A. Salama
  •  & Laura M. Calvi

• Review Article
  08 July 2023 | Open Access

  Effects of altered glycolysis levels on CD8⁺ T cell activation and function

  • Jiaying Cao
  • , Shan Liao
  •  & Yanhong Zhou

• Article
  08 June 2023 | Open Access

  Targeting pathogenic macrophages by the application of SHP-1 agonists reduces inflammation and alleviates pulmonary fibrosis

  • Shiao-Ya Hong
  • , Ya-Ting Lu
  •  & Kun-Lun Huang

• Article
  30 March 2023 | Open Access

  Influenza viral matrix 1 protein aggravates viral pathogenicity by inducing TLR4-mediated reactive oxygen species production and apoptotic cell death

  • Chang-Ung Kim
  • , Dahwan Lim
  •  & Doo-Jin Kim

• Article
  28 March 2023 | Open Access

  TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment

  • Wenchuan Zhou
  • , Yutong Zhou
  •  & Jing Li

• Article
  25 March 2023 | Open Access

  Mutations in the B30.2 and the central helical scaffold domains of pyrin differentially affect inflammasome activation

  • Daria Chirita
  • , Pauline Bronnec
  •  & Thomas Henry

• Article
  11 February 2023 | Open Access

  RIPK3 controls MAIT cell accumulation during development but not during infection

  • Timothy Patton
  • , Zhe Zhao
  •  & Alexandra J. Corbett

• Article
  06 February 2023 | Open Access

  Regulation of immunological tolerance by the p53-inhibitor iASPP

  • Elliot H. Akama-Garren
  • , Paul Miller
  •  & Xin Lu

• Article
  21 December 2022 | Open Access

  DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis

  • Maria Vedunova
  • , Victoria Turubanova
  •  & Dmitri V. Krysko

• Article
  01 December 2022 | Open Access

  Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage

  • Marta del Rio Oliva
  •  & Michael Basler

• Article
  01 October 2022 | Open Access

  GSDME deficiency leads to the aggravation of UVB-induced skin inflammation through enhancing recruitment and activation of neutrophils

  • Yujie Chen
  • , Ni Lian
  •  & Xu Chen

• Article
  27 August 2022 | Open Access

  Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c⁺ dendritic cells

  • Kurt T. K. Giuliani
  • , Anca Grivei
  •  & Andrew J. Kassianos

• Article
  15 August 2022 | Open Access

  PKR and TLR3 trigger distinct signals that coordinate the induction of antiviral apoptosis

  • Wenjie Zuo
  • , Mai Wakimoto
  •  & Takashi Fujita

• Review Article
  12 August 2022 | Open Access

  Chromatin-Associated Molecular Patterns (CAMPs) in sepsis

  • Colleen P. Nofi
  • , Ping Wang
  •  & Monowar Aziz

• Review Article
  22 July 2022 | Open Access

  Regulated necrosis, a proinflammatory cell death, potentially counteracts pathogenic infections

  • Guangzhi Zhang
  • , Jinyong Wang
  •  & Jiabo Ding

• Article
  14 July 2022 | Open Access

  Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis

  • Qi Cheng
  • , Mo Chen
  •  & Yan Du

• Article
  24 May 2022 | Open Access

  GSDMEa-mediated pyroptosis is bi-directionally regulated by caspase and required for effective bacterial clearance in teleost

  • Hang Xu
  • , Shuai Jiang
  •  & Li Sun

• Review Article
  13 May 2022 | Open Access

  Which cell death modality wins the contest for photodynamic therapy of cancer?

  • Tatiana Mishchenko
  • , Irina Balalaeva
  •  & Dmitri V. Krysko

• Article
  12 May 2022 | Open Access

  Tim-3⁺ decidual Mφs induced Th2 and Treg bias in decidual CD4⁺T cells and promoted pregnancy maintenance via CD132

  • Mengdie Li
  • , Fengrun Sun
  •  & Meirong Du

• Article
  19 April 2022 | Open Access

  Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages

  • Ji Cao
  • , Longlong Li
  •  & Haitian Ma

• Review Article
  16 April 2022 | Open Access

  Interaction between macrophages and ferroptosis

  • Yan Yang
  • , Yu Wang
  •  & Miao Yan

• Article
  25 March 2022 | Open Access

  STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)

  • Yasmine Messaoud-Nacer
  • , Elodie Culerier
  •  & Dieudonnée Togbe

• Article
  04 February 2022 | Open Access

  Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment

  • Vanessa Schimek
  • , Katharina Strasser
  •  & Rudolf Oehler

• Article
  03 February 2022 | Open Access

  E3 ubiquitin ligase SYVN1 is a key positive regulator for GSDMD-mediated pyroptosis

  • Yuhua Shi
  • , Yang Yang
  •  & Fushan Shi

• Article
  08 November 2021 | Open Access

  Proteomic analysis of necroptotic extracellular vesicles

  • Inbar Shlomovitz
  • , Ziv Erlich
  •  & Motti Gerlic

• Article
  30 October 2021 | Open Access

  TNF-α-induced protein 8-like 2 negatively regulates the immune function of dendritic cells by suppressing autophagy via the TAK1/JNK pathway in septic mice

  • Shuang-Qing Liu
  • , Chao Ren
  •  & Yong-Ming Yao

• Article
  29 October 2021 | Open Access

  CD8⁺ T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis

  • Neda Feizi
  • , Chiara Focaccetti
  •  & Silvia Piconese

• Article
  23 September 2021 | Open Access

  TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

  • Jerzy A. Woznicki
  • , Nisha Saini
  •  & Ken Nally

• Article
  23 September 2021 | Open Access

  SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury

  • Lin-Li Lv
  • , Cui Wang
  •  & Bi-Cheng Liu

• Article
  03 September 2021 | Open Access

  C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1⁺ M-MDSCs in relieving lupus-like symptoms

  • Dan Li
  • , Li Lu
  •  & Yayi Hou

• Article
  17 August 2021 | Open Access

  A Catalogus Immune Muris of the mouse immune responses to diverse pathogens

  • Céline Barlier
  • , Diego Barriales
  •  & Antonio del Sol