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| Open AccessCystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells
- Chenfeng Han
- , Minmin Ge
- & Lianjun Zhang
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Article
| Open AccessLncRNA Neat1 targets NonO and miR-128-3p to promote antigen-specific Th17 cell responses and autoimmune inflammation
- Sisi Chen
- , Jiali Wang
- & Hong Nian
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Article
| Open AccessMesenchymal stem cells empower T cells in the lymph nodes via MCP-1/PD-L1 axis
- Yifan He
- , Yan Qu
- & Songtao Shi
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Article
| Open AccessImmunomodulatory effect of NEDD8-activating enzyme inhibition in Multiple Myeloma: upregulation of NKG2D ligands and sensitization to Natural Killer cell recognition
- Sara Petillo
- , Cristina Capuano
- & Marco Cippitelli
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Article
| Open AccessEffects of short-chain fatty acids in inhibiting HDAC and activating p38 MAPK are critical for promoting B10 cell generation and function
- Fagui Zou
- , Yi Qiu
- & Jianbo Sun
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Article
| Open AccessTIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1
- Camille M. Lake
- , Kelsey Voss
- & Andrew L. Snow
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Article
| Open AccessMesenchymal stem cells alleviate experimental immune-mediated liver injury via chitinase 3-like protein 1-mediated T cell suppression
- Qiuli Liu
- , Xiaoyong Chen
- & Qi Zhang
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Article
| Open AccessEngineering of α-PD-1 antibody-expressing long-lived plasma cells by CRISPR/Cas9-mediated targeted gene integration
- Baohong Luo
- , Yikang Zhan
- & Hui Zhang
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Article
| Open AccessPDL1 blockage increases fetal resorption and Tfr cells but does not affect Tfh/Tfr ratio and B-cell maturation during allogeneic pregnancy
- Weihong Zeng
- , Shi Qin
- & Yi Lin
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Article
| Open AccessALG-2 couples T cell activation and apoptosis by regulating proteasome activity and influencing MCL1 stability
- Tian-Sheng He
- , Wangsheng Ji
- & Xinqi Liu
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Article
| Open AccessFibrotic liver microenvironment promotes Dll4 and SDF-1-dependent T-cell lineage development
- Zheng Gong
- , Bingxue Shang
- & Yufang Shi
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Article
| Open AccessThe homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors
- Maria Pia Abruzzese
- , Maria Teresa Bilotta
- & Marco Cippitelli
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Article
| Open AccessDifferential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4+Foxp3+ induced Treg cells in vitro and in vivo periphery in autoimmune diseases
- Sujuan Yang
- , Chichu Xie
- & Song Guo Zheng
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Original Article
| Open AccessProteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery
- Tiago Clemente
- , Narcisio J Vieira
- & Gustavo P Amarante-Mendes
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News and Commentary
| Open AccessDifferent death destinies: relative apoptosis sensitivity shapes the human effector CD8+ T-cell response derived from distinct memory subsets
- Andrew L Snow
- & Sasha E Larsen
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Original Article
| Open AccessAltered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses
- Isabel Cortegano
- , Mercedes Rodríguez
- & María Luisa Gaspar
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Original Article
| Open AccessIncreased tumor-infiltrating CD45RA−CCR7− regulatory T-cell subset with immunosuppressive properties foster gastric cancer progress
- Fang-yuan Mao
- , Hui Kong
- & Yuan Zhuang
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Original Article
| Open AccessMicroRNA-519a-3p mediates apoptosis resistance in breast cancer cells and their escape from recognition by natural killer cells
- Christian Breunig
- , Jens Pahl
- & Stefan Wiemann
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Original Article
| Open AccessT-cell autonomous death induced by regeneration of inert glucocorticoid metabolites
- Lourdes Rocamora-Reverte
- , Holger M Reichardt
- & GJan Wiegers
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Original Article
| Open AccessInterferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
- Purnima Bhat
- , Graham Leggatt
- & Ian H Frazer
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Original Article
| Open AccessHMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival
- Sonja M Lacher
- , Julia Bruttger
- & Ari Waisman
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Original Article
| Open AccessThe cryo-thermal therapy eradicated melanoma in mice by eliciting CD4+ T-cell-mediated antitumor memory immune response
- Kun He
- , Ping Liu
- & Lisa X Xu
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Original Article
| Open AccessIL-27 triggers IL-10 production in Th17 cells via a c-Maf/RORγt/Blimp-1 signal to promote the progression of endometriosis
- Kai-Kai Chang
- , Li-Bing Liu
- & Ming-Qing Li
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Review
| Open AccessAmino-acid transporters in T-cell activation and differentiation
- Wenkai Ren
- , Gang Liu
- & Yulong Yin
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Original Article
| Open AccessMesenchymal stromal cells inhibit CD25 expression via the mTOR pathway to potentiate T-cell suppression
- Hyun Seung Yoo
- , Kyuheon Lee
- & Myung-Shin Jeon
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Original Article
| Open AccessHetero-oligomerization between the TNF receptor superfamily members CD40, Fas and TRAILR2 modulate CD40 signalling
- Cristian R Smulski
- , Marion Decossas
- & Sylvie Fournel
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Original Article
| Open AccessTsc1 expression by dendritic cells is required to preserve T-cell homeostasis and response
- Yuechen Luo
- , Wenwen Li
- & Xiaoming Feng
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Original Article
| Open AccessBlock of both TGF-β and IL-2 signaling impedes Neurophilin-1+ regulatory T cell and follicular regulatory T cell development
- Liang Li
- , Shu-Han Yang
- & Zhe-Xiong Lian
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Original Article
| Open AccessKinase-independent function of RIP1, critical for mature T-cell survival and proliferation
- John P Dowling
- , Yubo Cai
- & Jianke Zhang
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News and Commentary
| Open AccessOxidative downmodulation of T cell-mediated cytotoxicity
- Guido H Wabnitz
- & Yvonne Samstag
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Original Article
| Open AccessMCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL
- Ingela B Vikström
- , Anne Slomp
- & David M Tarlinton
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Original Article
| Open AccessWASH has a critical role in NK cell cytotoxicity through Lck-mediated phosphorylation
- L Huang
- , P Zhu
- & Z Fan
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News and Commentary
| Open AccessThe APRIL paradox in normal versus malignant B cell biology
- M H A van Attekum
- , A P Kater
- & E Eldering
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Original Article
| Open AccessApoptotic CD8 T-lymphocytes disable macrophage-mediated immunity to Trypanosoma cruzi infection
- M P Cabral-Piccin
- , L V C Guillermo
- & M F Lopes
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Original Article
| Open AccessGlutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation
- D H Lee
- , D J Son
- & J T Hong
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Original Article
| Open AccessA novel differentiation pathway from CD4+ T cells to CD4− T cells for maintaining immune system homeostasis
- X Zhao
- , G Sun
- & D Zhang
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Original Article
| Open AccessLongitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection
- C Agrati
- , C Castilletti
- & M R Capobianchi
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Original Article
| Open AccessSmad4 represses the generation of memory-precursor effector T cells but is required for the differentiation of central memory T cells
- J Cao
- , X Zhang
- & J Zhang
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Original Article
| Open AccessDiscrete roles of canonical and non-canonical Wnt signaling in hematopoiesis and lymphopoiesis
- F Famili
- , B A E Naber
- & F J T Staal
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Original Article
| Open AccessFAS-ligand regulates differential activation-induced cell death of human T-helper 1 and 17 cells in healthy donors and multiple sclerosis patients
- M T Cencioni
- , S Santini
- & E Volpe
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Original Article
| Open AccessPD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy
- S-C Wang
- , Y-H Li
- & M-R Du
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Review
| Open AccessT-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance
- B Ye
- , X Liu
- & Y Chen
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Original Article
| Open AccessCBAP promotes thymocyte negative selection by facilitating T-cell receptor proximal signaling
- K-C Ho
- , Y-J Chiang
- & J J-Y Yen
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Original Article
| Open AccessIFN-γ induces aberrant CD49b+ NK cell recruitment through regulating CX3CL1: a novel mechanism by which IFN-γ provokes pregnancy failure
- Z-Y Li
- , H-H Chao
- & J-P Peng
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Original Article
| Open AccessTumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L
- M C Ramello
- , J Tosello Boari
- & C L Montes
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Original Article
| Open AccessNumb-dependent integration of pre-TCR and p53 function in T-cell precursor development
- N M Martin-Blanco
- , S Checquolo
- & I Screpanti
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Original Article
| Open AccessCD4+Foxp3+ regulatory T cell differentiation mediated by endometrial stromal cell-derived TECK promotes the growth and invasion of endometriotic lesions
- M-Q Li
- , Y Wang
- & D-J Li
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Original Article
| Open AccessHuman thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand
- D Nazzal
- , A Gradolatto
- & S Berrih-Aknin