Signal transduction articles within Cell Death & Disease

Featured

• Article
  21 April 2023 | Open Access

  Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection

  • Elien Eeckhout
  • , Lisa Hamerlinck
  •  & Andy Wullaert

• Article
  15 August 2022 | Open Access

  PKR and TLR3 trigger distinct signals that coordinate the induction of antiviral apoptosis

  • Wenjie Zuo
  • , Mai Wakimoto
  •  & Takashi Fujita

• Article
  14 July 2022 | Open Access

  Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis

  • Qi Cheng
  • , Mo Chen
  •  & Yan Du

• Article
  07 July 2022 | Open Access

  sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death

  • Zhenghao Wu
  • , Zhuoshuo Xu
  •  & Ping Lei

• Article
  28 March 2022 | Open Access

  LPS/Bcl3/YAP1 signaling promotes Sox9⁺HNF4α⁺ hepatocyte-mediated liver regeneration after hepatectomy

  • Changchun Shao
  • , Yingying Jing
  •  & Lixin Wei

• Article
  27 August 2021 | Open Access

  Extracellular vesicles package dsDNA to aggravate Crohn’s disease by activating the STING pathway

  • Fan Zhao
  • , Tao Zheng
  •  & Jianan Ren

• Article
  06 April 2021 | Open Access

  Membrane lymphotoxin-α₂β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist

  • Kirstin Kucka
  • , Isabell Lang
  •  & Harald Wajant

• Article
  04 May 2020 | Open Access

  Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

  • Yung-Hsuan Wu
  • , Ting-Fang Chou
  •  & Ming-Zong Lai

• Article
  23 March 2020 | Open Access

  Plasminogen is a master regulator and a potential drug candidate for the healing of radiation wounds

  • Mahsa Fallah
  • , Emil Viklund
  •  & Tor Ny

• Article
  11 February 2019 | Open Access

  Redundant and receptor-specific activities of TRADD, RIPK1 and FADD in death receptor signaling

  • Simone Füllsack
  • , Alevtina Rosenthal
  •  & Daniela Siegmund

• Article
  28 January 2019 | Open Access

  TRAIL inhibits RANK signaling and suppresses osteoclast activation via inhibiting lipid raft assembly and TRAF6 recruitment

  • Hsiu-Jung Liao
  • , Hwei-Fang Tsai
  •  & Ping-Ning Hsu

• Original Article
  02 November 2017 | Open Access

  Epothilone B impairs functional recovery after spinal cord injury by increasing secretion of macrophage colony-stimulating factor

  • Liang Mao
  • , Wei Gao
  •  & Xifan Mei

• Original Article
  05 October 2017 | Open Access

  Essential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathways

  • Puja Kumari
  • , Irene Saha
  •  & Himanshu Kumar

• News and Commentary
  31 August 2017 | Open Access

  Different death destinies: relative apoptosis sensitivity shapes the human effector CD8⁺ T-cell response derived from distinct memory subsets

  • Andrew L Snow
  •  & Sasha E Larsen

• Original Article
  17 August 2017 | Open Access

  Increased tumor-infiltrating CD45RA⁻CCR7⁻ regulatory T-cell subset with immunosuppressive properties foster gastric cancer progress

  • Fang-yuan Mao
  • , Hui Kong
  •  & Yuan Zhuang

• Review
  27 July 2017 | Open Access

  Acid sphingomyelinase mediates human CD4⁺ T-cell signaling: potential roles in T-cell responses and diseases

  • Aiping Bai
  •  & Yuan Guo

• Original Article
  20 July 2017 | Open Access

  T-cell autonomous death induced by regeneration of inert glucocorticoid metabolites

  • Lourdes Rocamora-Reverte
  • , Holger M Reichardt
  •  & GJan Wiegers

• Original Article
  08 June 2017 | Open Access

  ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65

  • Jun Meng
  • , Zhenyu Yao
  •  & Jinquan Cheng

• Review
  08 December 2016 | Open Access

  Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

  • Gerben Marsman
  • , Sacha Zeerleder
  •  & Brenda M Luken

• News and Commentary
  21 July 2016 | Open Access

  Harnessing downstream NF-κB signalling to achieve apoptosis-inducing anti-cancer-specific activity

  • M Vaccarezza
  •  & M Vitale

• Original Article
  21 July 2016 | Open Access

  TWEAK favors phosphate-induced calcification of vascular smooth muscle cells through canonical and non-canonical activation of NFκB

  • L Hénaut
  • , A B Sanz
  •  & A Ortiz

• Original Article
  12 May 2016 | Open Access

  GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation

  • S Ito
  • , Y Tanaka
  •  & K-I Isobe

• Original Article
  10 March 2016 | Open Access

  The oncolytic peptide LTX-315 triggers immunogenic cell death

  • H Zhou
  • , S Forveille
  •  & G Kroemer

• Original Article
  09 October 2014 | Open Access

  c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells

  • C Geismann
  • , F Grohmann
  •  & A Arlt

• Original Article
  29 May 2014 | Open Access

  Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef

  • M Hashimoto
  • , H Nasser
  •  & S Suzu

• Original Article
  15 May 2014 | Open Access

  HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination

  • T Li
  • , J Guan
  •  & X Zheng

• Original Article
  08 May 2014 | Open Access

  Fas-associated factor (Faf1) is a novel CD40 interactor that regulates CD40-induced NF-κB activation via a negative feedback loop

  • T Elmetwali
  • , L S Young
  •  & D H Palmer

• Original Article
  13 March 2014 | Open Access

  Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge

  • P G Través
  • , V Pardo
  •  & L Boscá

• Original Article
  27 February 2014 | Open Access

  MicroRNA-21 regulates T-cell apoptosis by directly targeting the tumor suppressor gene Tipe2

  • Q Ruan
  • , P Wang
  •  & Y H Chen

• Original Article
  09 January 2014 | Open Access

  Adenosine 5′-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice

  • Y Zhan
  • , Z Wang
  •  & J Zhang

• Original Article
  19 December 2013 | Open Access

  Identification of the NF-κB inhibitor A20 as a key regulator for human adipogenesis

  • A Dorronsoro
  • , V Lang
  •  & C Trigueros

• Original Article
  28 February 2013 | Open Access

  Nuclear factor-κB modulates osteogenesis of periodontal ligament stem cells through competition with β-catenin signaling in inflammatory microenvironments

  • X Chen
  • , C Hu
  •  & Y Jin

• Original Article
  17 November 2011 | Open Access

  TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

  • N Vanlangenakker
  • , M J M Bertrand
  •  & T Vanden Berghe

• Original Article
  03 November 2011 | Open Access

  TRAIL promotes caspase-dependent pro-inflammatory responses via PKCδ activation by vascular smooth muscle cells

  • S Song
  • , K Choi
  •  & C Choi

• Original Article
  18 August 2011 | Open Access

  TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms

  • H Rauert
  • , T Stühmer
  •  & D Siegmund

• News and Commentary
  24 March 2011 | Open Access

  Distinct roles for the cellular inhibitors of apoptosis proteins 1 and 2

  • T E Graber
  •  & M Holcik

• Original Article
  04 November 2010 | Open Access

  The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury

  • A Lanzillotta
  • , I Sarnico
  •  & M Pizzi

• Original Article
  07 October 2010 | Open Access

  Inhibition of NF-κB activation sensitizes U937 cells to 3′-azido-3′-deoxythymidine induced apoptosis

  • C Matteucci
  • , A Minutolo
  •  & A Mastino

• Original Article
  13 May 2010 | Open Access

  p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

  • D Meley
  • , D G Spiller
  •  & V Sée