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| Open AccessKnockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages
- Changjian Zhu
- , Ruilin Zheng
- & Yi Zhou
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Article
| Open AccessReg4 deficiency aggravates pancreatitis by increasing mitochondrial cell death and fibrosis
- Weihui Yan
- , Ying Wang
- & Yongtao Xiao
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Article
| Open AccessResolvin E1 improves efferocytosis and rescues severe aplastic anemia in mice
- Rachel Grazda
- , Allison N. Seyfried
- & Katherine C. MacNamara
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Article
| Open AccessTrauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes
- Julian Roos
- , Julia Zinngrebe
- & Pamela Fischer-Posovszky
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Article
| Open AccessThe broad impact of cell death genes on the human disease phenome
- Abigail L. Rich
- , Phillip Lin
- & Sandra S. Zinkel
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Article
| Open AccessLoss of macrophage TSC1 exacerbates sterile inflammatory liver injury through inhibiting the AKT/MST1/NRF2 signaling pathway
- Ming Ni
- , Jiannan Qiu
- & Qiang Zhu
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Article
| Open AccessCrosstalk of HDAC4, PP1, and GSDMD in controlling pyroptosis
- Weilv Xu
- , Qiao Jin
- & Fushan Shi
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Article
| Open AccessGITRL impairs hepatocyte repopulation by liver progenitor cells to aggravate inflammation and fibrosis by GITR+CD8+ T lymphocytes in CDE Mice
- Li Li
- , Yu He
- & Ping Wang
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Article
| Open AccessMETTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner
- Fei Cao
- , Guojun Chen
- & Jingdun Xie
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Article
| Open AccessE3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis
- Yingjie Huang
- , Tao Chen
- & Yong Li
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Article
| Open AccessAirway epithelial cGAS inhibits LPS-induced acute lung injury through CREB signaling
- Zhangchu Jin
- , Zhehua Shao
- & Fugui Yan
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Article
| Open AccessThe C-type lectin COLEC10 is predominantly produced by hepatic stellate cells and involved in the pathogenesis of liver fibrosis
- Mengfan Zhang
- , Yang Jing
- & Jianzhuang Ren
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Article
| Open AccessSulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signaling
- Chujun Ma
- , Chaode Gu
- & Zhonglan Su
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Article
| Open AccessNINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis
- Yves Dondelinger
- , Dario Priem
- & Mathieu J. M. Bertrand
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Article
| Open AccessBRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury
- Wen Zhang
- , Kai Liu
- & Rong-Hua Yin
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Article
| Open AccessGasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection
- Sarah Rosli
- , Christopher M. Harpur
- & Michelle D. Tate
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Article
| Open AccessInflammasome activation occurs in CD4+ and CD8+ T cells during graft-versus-host disease
- Sarah Talley
- , David J. Rademacher
- & Edward M. Campbell
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Article
| Open AccessInterfering with Rac1-activation during neonatal monocyte-macrophage differentiation influences the inflammatory responses of M1 macrophages
- Hang Fu
- , Ping Zhang
- & Xiao-Yun Zhong
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Article
| Open AccessInhibition of cGAS–STING pathway alleviates neuroinflammation-induced retinal ganglion cell death after ischemia/reperfusion injury
- Xingdi Wu
- , Naiji Yu
- & Kaijun Wang
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Article
| Open AccessCXCR1 drives the pathogenesis of EAE and ARDS via boosting dendritic cells-dependent inflammation
- Wei Zhuang
- , Jinfeng Zhou
- & Changsheng Du
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Article
| Open AccessGasdermin D-mediated keratinocyte pyroptosis as a key step in psoriasis pathogenesis
- Ni Lian
- , Yujie Chen
- & Xu Chen
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Article
| Open AccessOTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
- Lien Verboom
- , Christopher J. Anderson
- & Geert van Loo
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Article
| Open AccessInhibition of autotaxin alleviates pathological features of hepatic encephalopathy at the level of gut–liver–brain axis: an experimental and bioinformatic study
- Ali Sepehrinezhad
- , Ali Shahbazi
- & Sajad Sahab Negah
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Review Article
| Open AccessPyroptosis in renal inflammation and fibrosis: current knowledge and clinical significance
- Ya Liu
- , Haibo Lei
- & Yixiang Hu
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Article
| Open AccessGOLPH3 promotes endotoxemia-induced liver and kidney injury through Golgi stress-mediated apoptosis and inflammatory response
- Theodomir Dusabimana
- , Jihyun Je
- & Sang Won Park
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Perspective
| Open AccessBalancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy
- Carolina Cattoni Koh
- , Kenneth J. Gollob
- & Walderez O. Dutra
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Article
| Open AccessB cell-derived IL-10 promotes the resolution of lipopolysaccharide-induced acute lung injury
- Zhun Sun
- , Anning Chen
- & Guojun Qian
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Article
| Open AccessIF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype
- Sonia Domínguez-Zorita
- , Inés Romero-Carramiñana
- & José M. Cuezva
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Article
| Open AccessATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury
- Ranran Li
- , Mei Meng
- & Lei Li
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Article
| Open AccessE3 ligase HECTD3 promotes RNA virus replication and virus-induced inflammation via K33-linked polyubiquitination of PKR
- Jiaying Huang
- , Zhou Yu
- & Xuetao Cao
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Article
| Open AccessAAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice
- Shijie Zhang
- , Xiang Tong
- & Hong Fan
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Article
| Open AccessRNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury
- Pei-Yao Liu
- , Chih-Yuan Chen
- & Ying-Chuan Chen
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Article
| Open AccessButyrate limits inflammatory macrophage niche in NASH
- Ankita Sarkar
- , Priya Mitra
- & Partha Chakrabarti
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Article
| Open AccessTLR7-MyD88-DC-CXCL16 axis results neutrophil activation to elicit inflammatory response in pustular psoriasis
- Jiajing Lu
- , Xiaoyuan Zhong
- & Yuling Shi
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Article
| Open AccessXIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death
- Axel Witt
- , Tatiana Goncharov
- & Domagoj Vucic
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Article
| Open AccessInfluenza viral matrix 1 protein aggravates viral pathogenicity by inducing TLR4-mediated reactive oxygen species production and apoptotic cell death
- Chang-Ung Kim
- , Dahwan Lim
- & Doo-Jin Kim
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Article
| Open AccessRIP3-mediated microglial necroptosis promotes neuroinflammation and neurodegeneration in the early stages of diabetic retinopathy
- Zijing Huang
- , Jiajian Liang
- & Dingguo Huang
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Article
| Open AccessDeletion of Gpatch2 does not alter Tnf expression in mice
- Destiny Dalseno
- , Holly Anderton
- & Philippe Bouillet
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Article
| Open AccessGPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway
- Guoqiang Fan
- , Yanfei Li
- & Xiaojing Yang
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Review Article
| Open AccessThe interaction between ferroptosis and inflammatory signaling pathways
- Yue Chen
- , Ze-Min Fang
- & Ding-Sheng Jiang
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Article
| Open AccessTissue transglutaminase exacerbates renal fibrosis via alternative activation of monocyte-derived macrophages
- Yoshiki Shinoda
- , Hideki Tatsukawa
- & Kiyotaka Hitomi
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Article
| Open AccessNecroptosis of macrophage is a key pathological feature in biliary atresia via GDCA/S1PR2/ZBP1/p-MLKL axis
- Shen Yang
- , Na Chang
- & Liying Li
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Article
| Open AccessMLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10
- Cheng Peng
- , Guangping Tu
- & Xiao Yu
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Article
| Open AccessCD11c+ microglia promote white matter repair after ischemic stroke
- Junqiu Jia
- , Lili Zheng
- & Meijuan Zhang
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Article
| Open AccessSchwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury
- Jie Ren
- , Bin Zhu
- & Shiqing Feng
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Article
| Open AccessIntrastriatal injection of Parkinson’s disease intestine and vagus lysates initiates α-synucleinopathy in rat brain
- Zhaofei Yang
- , Ying Wang
- & Weidong Le
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Article
| Open AccessHigh p62 expression suppresses the NLRP1 inflammasome and increases stress resistance in cutaneous SCC cells
- Paulina Hennig
- , Michela Di Filippo
- & Hans-Dietmar Beer
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Article
| Open AccessLysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1β secretion
- Laura Migliari Branco
- , Marcelo Pires Amaral
- & Karina Ramalho Bortoluci
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Article
| Open AccessInhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice
- A. Farini
- , L. Tripodi
- & Y. Torrente