Immunological disorders articles within Cell Death & Disease

Featured

• Article
  18 May 2024 | Open Access

  Macrophages communicate with mesangial cells through the CXCL12/DPP4 axis in lupus nephritis pathogenesis

  • Weiwei Li
  • , Chun Yao
  •  & Zhanyun Da

• Article
  12 March 2024 | Open Access

  Single-cell RNA-seq reveals keratinocyte and fibroblast heterogeneity and their crosstalk via epithelial-mesenchymal transition in psoriasis

  • Dianhao Guo
  • , Xiaokang Li
  •  & Ningning Dang

• Article
  01 March 2024 | Open Access

  Gasdermin E promotes translocation of p65 and c-jun into nucleus in keratinocytes for progression of psoriatic skin inflammation

  • Fangyuan Long
  • , Xuecui Wei
  •  & Xu Chen

• Article
  08 February 2024 | Open Access

  Saracatinib inhibits necroptosis and ameliorates psoriatic inflammation by targeting MLKL

  • Jingyi Li
  • , Xingfeng Liu
  •  & Lisheng Li

• Article
  24 January 2024 | Open Access

  HECTD3 inhibits NLRP3 inflammasome assembly and activation by blocking NLRP3-NEK7 interaction

  • Zhuo Cheng
  • , Maobo Huang
  •  & Ceshi Chen

• Article
  13 November 2023 | Open Access

  Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation

  • Jing Zhang
  • , Longmin Chen
  •  & Cong-Yi Wang

• Article
  11 October 2023 | Open Access

  Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis

  • Qiong Wu
  • , Zongwen Liang
  •  & Yingying Cao

• Article
  16 September 2023 | Open Access

  LncRNA Neat1 targets NonO and miR-128-3p to promote antigen-specific Th17 cell responses and autoimmune inflammation

  • Sisi Chen
  • , Jiali Wang
  •  & Hong Nian

• Article
  09 June 2023 | Open Access

  SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis

  • Tao Huang
  • , Shijun Chen
  •  & Zhili Rong

• Article
  20 April 2023 | Open Access

  LncRNA UCA1 promotes keratinocyte-driven inflammation via suppressing METTL14 and activating the HIF-1α/NF-κB axis in psoriasis

  • Yibo Hu
  • , Li Lei
  •  & Jing Chen

• Article
  19 April 2023 | Open Access

  Plasma metabolomic characterization of SARS-CoV-2 Omicron infection

  • Xue Li
  • , Yimeng Liu
  •  & Huaiyong Chen

• Article
  25 March 2023 | Open Access

  Mutations in the B30.2 and the central helical scaffold domains of pyrin differentially affect inflammasome activation

  • Daria Chirita
  • , Pauline Bronnec
  •  & Thomas Henry

• Article
  08 March 2023 | Open Access

  WFDC12-overexpressing contributes to the development of atopic dermatitis via accelerating ALOX12/15 metabolism and PAF accumulation

  • Guolin Li
  • , Linna Gu
  •  & Jiong Li

• Article
  09 February 2023 | Open Access

  Elevated fatty acid β-oxidation by leptin contributes to the proinflammatory characteristics of fibroblast-like synoviocytes from RA patients via LKB1-AMPK pathway

  • Jing Wei
  • , Xinxin Huang
  •  & Xia Li

• Article
  06 February 2023 | Open Access

  FcγRIIIA activation-mediated up-regulation of glycolysis alters MDSCs modulation in CD4⁺ T cell subsets of Sjögren syndrome

  • Jingjing Qi
  • , Xinyang Zhou
  •  & Xia Li

• Article
  28 January 2023 | Open Access

  Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction

  • Hongwei Lin
  • , Jing Lin
  •  & Yongping Chen

• Article
  25 November 2022 | Open Access

  Mesenchymal stem/stromal cells primed by inflammatory cytokines alleviate psoriasis-like inflammation via the TSG-6-neutrophil axis

  • Yayun Ding
  • , Pixia Gong
  •  & Yufang Shi

• Article
  22 October 2022 | Open Access

  Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1

  • Christine Engelmann
  • , Patrick Schuhmachers
  •  & Christian Münz

• Article
  10 September 2022 | Open Access

  PLGA-microspheres-carried circGMCL1 protects against Crohn’s colitis through alleviating NLRP3 inflammasome-induced pyroptosis by promoting autophagy

  • Jie Zhao
  • , Ye Sun
  •  & Liming Tang

• Article
  21 July 2022 | Open Access

  SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction

  • Huaping Zheng
  • , Linna Gu
  •  & Jiong Li

• Article
  11 June 2022 | Open Access

  DNMT3b protects centromere integrity by restricting R-loop-mediated DNA damage

  • Hsueh-Tzu Shih
  • , Wei-Yi Chen
  •  & Zee-Fen Chang

• Article
  14 May 2022 | Open Access

  Sex differences in global metabolomic profiles of COVID-19 patients

  • Rocio Diaz Escarcega
  • , Pedram Honarpisheh
  •  & Andrey S. Tsvetkov

• Article
  15 March 2022 | Open Access

  Dopamine D3 receptor signaling alleviates mouse rheumatoid arthritis by promoting Toll-like receptor 4 degradation in mast cells

  • Biao Wang
  • , Xueyi Li
  •  & Li Xue

• Article
  28 January 2022 | Open Access

  TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis

  • Jian-Hong Shi
  • , Chen Ling
  •  & Zhi-Yu Ni

• Article
  27 January 2022 | Open Access

  Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38⁺ macrophages and NAD⁺ decline

  • Elena Ciaglia
  • , Valentina Lopardo
  •  & Annibale Alessandro Puca

• Review Article
  24 January 2022 | Open Access

  Advances in the pathogenesis of psoriasis: from keratinocyte perspective

  • Xue Zhou
  • , Youdong Chen
  •  & Chunyuan Guo

• Article
  30 October 2021 | Open Access

  TNF-α-induced protein 8-like 2 negatively regulates the immune function of dendritic cells by suppressing autophagy via the TAK1/JNK pathway in septic mice

  • Shuang-Qing Liu
  • , Chao Ren
  •  & Yong-Ming Yao

• Article
  29 October 2021 | Open Access

  CD8⁺ T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis

  • Neda Feizi
  • , Chiara Focaccetti
  •  & Silvia Piconese

• Review Article
  15 October 2021 | Open Access

  A long way to go: caspase inhibitors in clinical use

  • Shanel Dhani
  • , Yun Zhao
  •  & Boris Zhivotovsky

• Article
  23 September 2021 | Open Access

  TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

  • Jerzy A. Woznicki
  • , Nisha Saini
  •  & Ken Nally

• Article
  12 June 2021 | Open Access

  TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice

  • Nour Al-Zaeed
  • , Zsófia Budai
  •  & Zsolt Sarang

• Article
  07 June 2021 | Open Access

  Effects of short-chain fatty acids in inhibiting HDAC and activating p38 MAPK are critical for promoting B10 cell generation and function

  • Fagui Zou
  • , Yi Qiu
  •  & Jianbo Sun

• Article
  14 May 2021 | Open Access

  The endoribonuclease N4BP1 prevents psoriasis by controlling both keratinocytes proliferation and neutrophil infiltration

  • Chenliang Gou
  • , Wenkai Ni
  •  & Yihui Fan

• Article
  06 May 2021 | Open Access

  Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells

  • Yuge Gao
  • , Xinyu Yao
  •  & Yizhou Hu

• Article
  30 April 2021 | Open Access

  Bruton’s tyrosine kinase regulates gut immune homeostasis through attenuating Th1 response

  • Di Guan
  • , Zixi Wang
  •  & Kong-Peng Lam

• Article
  04 March 2021 | Open Access

  Small intestinal immune-environmental changes induced by oral tolerance inhibit experimental atopic dermatitis

  • Han-Na Um
  • , Jin-Ok Baek
  •  & YunJae Jung

• Article
  12 February 2021 | Open Access

  CHBP induces stronger immunosuppressive CD127⁺ M-MDSC via erythropoietin receptor

  • Jiawei Li
  • , Guowei Tu
  •  & Ruiming Rong

• Perspective
  27 January 2021 | Open Access

  DAMPs released by pyroptotic cells as major contributors and therapeutic targets for CAR-T-related toxicities

  • Tian Deng
  • , Chao Tang
  •  & Xiaochun Wan

• Article
  11 January 2021 | Open Access

  The HIV protease inhibitor Saquinavir attenuates sepsis-induced acute lung injury and promotes M2 macrophage polarization via targeting matrix metalloproteinase-9

  • Yao Tong
  • , Zhuang Yu
  •  & Quan Li

• Article
  11 January 2021 | Open Access

  Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

  • Zhihao Xu
  • , Ying Zhou
  •  & Tengchuan Jin

• Article
  06 January 2021 | Open Access

  Gefitinib initiates sterile inflammation by promoting IL-1β and HMGB1 release via two distinct mechanisms

  • Takuya Noguchi
  • , Yuto Sekiguchi
  •  & Atsushi Matsuzawa

• Article
  04 January 2021 | Open Access

  Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation

  • Karla C. Fischer
  • , Carmel P. Daunt
  •  & Anissa M. Jabbour

• Article
  24 October 2020 | Open Access

  Metabolic defects in splenic B cell compartments from patients with liver cirrhosis

  • Man Huang
  • , Xiaoju Liu
  •  & Zheng Zhang

• Article
  03 October 2020 | Open Access

  EZH2-dependent epigenetic modulation of histone H3 lysine-27 contributes to psoriasis by promoting keratinocyte proliferation

  • Tongmei Zhang
  • , Luting Yang
  •  & Gang Wang

• Article
  16 September 2020 | Open Access

  PKC-δ deficiency in B cells displays osteopenia accompanied with upregulation of RANKL expression and osteoclast–osteoblast uncoupling

  • Shangfu Li
  • , Qiuli Liu
  •  & Limin Rong

• Article
  13 August 2020 | Open Access

  Costello syndrome model mice with a Hras G12S mutation are susceptible to develop house dust mite-induced atopic dermatitis

  • Yu Katata
  • , Shin-ichi Inoue
  •  & Yoko Aoki

• Article
  02 June 2020 | Open Access

  mTOR-Myc axis drives acinar-to-dendritic cell transition and the CD4⁺ T cell immune response in acute pancreatitis

  • Dan Xu
  • , Rongli Xie
  •  & Jian Fei

• Article
  02 June 2020 | Open Access

  RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease

  • Jia Guo
  • , Min Lei
  •  & Zhangsuo Liu

• Article
  30 April 2020 | Open Access

  Keratinocyte transglutaminase 2 promotes CCR6⁺ γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation

  • Ji-Woong Shin
  • , Mee-ae Kwon
  •  & In-Gyu Kim

• Article
  24 April 2020 | Open Access

  FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress

  • Kyoung Woo Kim
  • , Jin Suk Ryu
  •  & Joo Youn Oh