Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
In this Review, Rosenthal, Asua and Conrad summarize our current knowledge of artemisinin partial resistance and focus on the emergence of resistance in Africa, including its epidemiology and transmission dynamics, and mechanisms of resistance.
This study describes a signalling pathway involving the host receptor GPR35 and members of the gut microbiota, such as Parabacteroides distasonis, which regulates depressive-like behaviour.
This study reports that antibodies that target the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal simian-HIV challenge.
In this Review, Jones, Marken and Silver develop a conceptual framework for synthetic microbiology organized into three domains — factory, farm and field — to explore the utility of synthetic microbiology in addressing sustainability challenges, and examine several examples of microbial engineering applications relevant to each domain.
This study describes Bdellovibrio bacteriovorus trimeric fibre proteins with diverse adhesive tips that enable the identification of a broad range of prey.
In this Review, Thiel and colleagues summarize our emerging knowledge of the SARS-CoV-2 intracellular life cycle and the molecular functions of the viral proteins, as well as their interaction with the host cell.
In this Review, Roussin-Léveillée, Mackey and colleagues examine microorganism interaction with and manipulation of the plant apoplast. Effector-driven extracellular niche establishment is conceptualized as foundational to plant pathogenesis and frames the discussion of the complex interplay between pathogen virulence, host immunity and the physiological dynamics shaping plant–microorganism interactions.
In this Review, Meyerowitz et al. examine the clinical presentations of COVID-19 in the era of widespread population immunity and explore current approaches to managing COVID-19 across different patient groups.
In this study, Ratiner et al. examine the advantages, challenges and future perspectives of utilizing microbiome data in personalized medicine for optimal patient care.
In this Review, Jassey and Jackson explore the intricate relationship between viruses and the autophagic pathway, highlighting how viruses either exploit or manipulate the autophagy pathway to influence their replication and survival within host cells.
Two recent studies provide mechanistic understanding of how bacteria employ the Gabija system for defence against phages, as well as how phages use anti-defence proteins to overcome bacterial immunity.
In this Review, Tan and colleagues highlight recent efforts to discover non-traditional antimicrobials and explore the therapeutic potential of antimicrobial peptides and macrocycles, antibodies, bacteriophages and antisense-based therapeutics, focusing on how current research efforts are pushing these technologies towards clinical implementation.
In this study, Lee et al. analyse the structure and receptor-binding features of the spike glycoprotein from a clade 3 sarbecovirus to examine the risk of spillover from bats to humans.
In this Review, Motta and Moran explore recent research investigating the role of the gut microbiota in honeybee biology and health, as well as the environmental factors that can impair the microbiota and the potential strategies to restore a perturbed microbiota in honeybees.
