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  • In this study, Armani-Tourret et al. show that the combination of panobinostat and pegylated interferon-α2a transforms the structure and composition of the HIV-1 reservoir and could potentially counter it.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Liu et al. explore the interplay between a fungal effector and a plant cysteine protease and design a small-molecule compound aimed at targeting this effector to combat rice blast disease.

    • Agustina Taglialegna
    Research Highlight
  • In this Journal Club, Salvador Almagro-Moreno discusses a study by Kirn et al., which explores the emergence of virulence traits in Vibrio cholerae and demonstrates how the ability of this pathogen to colonize the host shares a common mechanism to its capacity to thrive in natural environments.

    • Salvador Almagro-Moreno
    Journal Club
  • Wastewater genomic surveillance can transform global viral disease monitoring. This Genome Watch article explores the techniques, analytical pipelines and implications for public health.

    • Arin Wongprommoon
    • Chalita Chomkatekaew
    • Claire Chewapreecha
    Genome Watch
  • In this study, Achberger et al. report that microbial communities of inactive hydrothermal deposits contribute to primary productivity in the deep sea.

    • Agustina Taglialegna
    Research Highlight
  • This month’s Genome Watch discusses the application of spatial transcriptomics to investigate the arrangements of microbial communities and their effects on the host.

    • Matthew J. Blow
    Genome Watch
  • The study provides insights into how insects and their endosymbionts can manipulate plant defences.

    • Andrea Du Toit
    Research Highlight
  • This study shows that the distinct cellular organization across the depth of a biofilm is tightly regulated and has consequences for cell physiology and antibiotic tolerance.

    • Andrea Du Toit
    Research Highlight
  • This study describes a signalling pathway involving the host receptor GPR35 and members of the gut microbiota, such as Parabacteroides distasonis, which regulates depressive-like behaviour.

    • Agustina Taglialegna
    Research Highlight
  • This study reports that antibodies that target the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal simian-HIV challenge.

    • Andrea Du Toit
    Research Highlight
  • This study describes Bdellovibrio bacteriovorus trimeric fibre proteins with diverse adhesive tips that enable the identification of a broad range of prey.

    • Andrea Du Toit
    Research Highlight
  • In this study, Knödlseder et al. explore the potential of an engineered Cutibacterium acnes strain as a microbiome-based therapy for skin conditions.

    • Agustina Taglialegna
    Research Highlight
  • Two recent studies provide mechanistic understanding of how bacteria employ the Gabija system for defence against phages, as well as how phages use anti-defence proteins to overcome bacterial immunity.

    • Agustina Taglialegna
    Research Highlight
  • The data of the study suggest that bacteria possess a physiological iron memory that persists over multiple generations.

    • Andrea Du Toit
    Research Highlight
  • In this study, Lee et al. analyse the structure and receptor-binding features of the spike glycoprotein from a clade 3 sarbecovirus to examine the risk of spillover from bats to humans.

    • Agustina Taglialegna
    Research Highlight