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The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

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News & Comment



Caio Bracey


Fuelled by increasing obesity rates, NAFLD has emerged as a leading global cause of chronic liver disease in the past few decades. Despite growing prevalence, the factors influencing NAFLD development and subsequent progression to NASH, liver fibrosis, cirrhosis and hepatocellular carcinoma are poorly understood. In this article series, Nature Reviews Gastroenterology & Hepatology explores the epidemiology of NAFLD, disease mechanisms and therapeutics, and clinical approaches to diagnosis and management.

Hugh Thomas

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