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Our Ig Nobel Prize-winning smart toilet research confronts societal taboos and uses humour as a gateway to advance serious dialogue about health technology. It is a call to action to embrace innovation, foster richer scientific discussions and support pioneering research for tangible health advancements.
A new study by Díaz and colleagues links strong alcohol policy with improved health and societal outcomes. The evidence for what works to reduce the enormous burden from alcohol is clear. The question is why are governments still not acting?
The gut microbiota is an important modulator of the gut–brain axis. This Review provides an overview of barrier function across this axis and examines the role of the gut microbiota in communication across and between these specialized gastrointestinal and brain barriers in health and disease.
Fermented foods have gained renewed popularity owing to their health-promoting potential. This Review discusses the mechanisms underlying the benefits of fermented foods in gut health and disease, highlighting how specific fermented food microorganisms, food components and bioactive compounds exert their effects. A future outlook on research is also detailed.
RNA modifications are crucial in regulating mRNA translation. This Review provides a comprehensive overview of the molecular mechanisms underlying RNA modifications in mRNA translation regulation, and discusses the diagnostic and therapeutic potentials of targeting RNA modifications for liver cancer management.
In this Review, Argüero and Sifrim describe the core pathophysiological mechanisms involved in gastro-oesophageal reflux disease (GERD). They also discuss the implications for clinical management of GERD.
