Volume 2 Issue 6, June 2000

Montage of images that together provide evidence that the γ-tubulin ring complex (γTURC) forms a helical template for microtubule nucleation. These include: immunofluorescence images of microtubules (red) with ends labelled for γTURC components (green); electron micrographs of microtubules (cyan), minus-end labelled with gold particles (yellow) conjugated to antibodies against γTURC components (antibody 'shell' shown as red rings); and tomographic reconstruction of a purified Drosophila γTURC (light green). [Cover design: Majo Xeridat] [article, p. 352, 358 and 365; news and views, p.E93].

Article

Discrete interactions in cell adhesion measured by single-molecule force spectroscopy

Martin Benoit
Daniela Gabriel
Hermann E. Gaub
Article 28 Apr 2000
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Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

Shigemi Matsuyama
Juan Llopis
John C. Reed
Article 28 Apr 2000
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

Anne Bertolotti
Yuhong Zhang
David Ron

Focus:

Celebrating 25 years of cell biology
Article 08 May 2000
Cargo binding and regulatory sites in the tail of fungal conventional kinesin

Stephan Seiler
Jochen Kirchner
Manfred Schliwa
Article 09 May 2000
Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents

Weiming Xu
Lizhi Liu
lan G. Charles
Article 10 May 2000
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

Kimberly Burns
Jonathan Clatworthy
Filippo Volpe
Article 10 May 2000
Immunostructural evidence for the template mechanism of microtubule nucleation

Thomas J. Keating
Gary G. Borisy
Article 12 May 2000
A new function for the γ -tubulin ring complex as a microtubule minus-end cap

Christiane Wiese
Yixian Zheng
Article 12 May 2000
Structure of the γ-tubulin ring complex: a template for microtubule nucleation

Michelle Moritz
Michael B. Braunfeld
David A. Agard
Article 12 May 2000
Smooth-muscle contraction without smooth-muscle myosin

Ingo Morano
Gui-Xuan Chai
Michael Bader
Article 12 May 2000

Top of page ⤴

Brief Communication

Latrunculin alters the actin-monomer subunit interface to prevent polymerization

Walter M. Morton
Kathryn R. Ayscough
Paul J. McLaughlin
Brief Communication 12 May 2000

Top of page ⤴

Editorial

Drowning by numbers

Editorial 01 Jun 2000

Top of page ⤴

News & Views

γ-tubulin nucleation: template or protofilament?

Harold P. Erickson
News & Views 01 Jun 2000
Convergence of DNA repair and cell-cycle checkpoint control

Angela Eggleston
News & Views 01 Jun 2000
It’s a kar9ochore to capture microtubules

Kerry Bloom
News & Views 01 Jun 2000
Different site, different splice

Tom Misteli
News & Views 01 Jun 2000
Drosophila p53: meeting the Grim Reaper

Hermann Steller
News & Views 01 Jun 2000
COP1 patrols the night beat

Raymond J. Deshaies
Elliot Meyerowitz
News & Views 01 Jun 2000
“Eat me”signals of apoptotic bodies

Valerie Depraetere
News & Views 01 Jun 2000
Giving protein traffic the green light

Linda M. Hendershot
News & Views 01 Jun 2000

Top of page ⤴

Review Article

To be or not to be in the nucleolus

Maria Carmo-Fonseca
Luís Mendes-Soares
Isabel Campos
Review Article 01 Jun 2000

Top of page ⤴

Volume 2 Issue 6, June 2000

Article

Discrete interactions in cell adhesion measured by single-molecule force spectroscopy

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

Cargo binding and regulatory sites in the tail of fungal conventional kinesin

Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

Immunostructural evidence for the template mechanism of microtubule nucleation

A new function for the γ -tubulin ring complex as a microtubule minus-end cap

Structure of the γ-tubulin ring complex: a template for microtubule nucleation

Smooth-muscle contraction without smooth-muscle myosin

Brief Communication

Latrunculin alters the actin-monomer subunit interface to prevent polymerization

Editorial

Drowning by numbers

News & Views

γ-tubulin nucleation: template or protofilament?

Convergence of DNA repair and cell-cycle checkpoint control

It’s a kar9ochore to capture microtubules

Different site, different splice

Drosophila p53: meeting the Grim Reaper

COP1 patrols the night beat

“Eat me”signals of apoptotic bodies

Giving protein traffic the green light

Review Article

To be or not to be in the nucleolus

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