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A machine learning model for generating crop-specific and spatially explicit NH3 emission factors globally shows that global NH3 emissions in 2018 were lower than previous estimates that did not fully consider fertilizer management practices.
Proferroptotic activity of 7-dehydrocholesterol reductase is shown along with an unexpected prosurvival function of its substrate, 7-dehydrocholesterol, indicating a cell-intrinsic mechanism that could be used by cancer cells to protect phospholipids from oxidative damage and escape ferroptosis.
Structural changes mediated by advanced glycation end-products enhance extracellular matrix viscoelasticity, and that viscoelasticity can promote cancer progression in vivo, independent of stiffness.
Excitonic single-photon superradiance is reported in individual perovskite quantum dots with a sub-100 ps radiative decay time, almost as short as the reported exciton coherence time.
Neuropixels recordings from the language-dominant prefrontal cortex reveal a structured organization of planned words, an encoding cascade of phonetic representations by prefrontal neurons in humans and a cellular process that could support the production of speech.
Serial femtosecond crystallography reveals the structural dynamics of photosystem II during the S-state transitions that produce dioxygen, providing insight into electron transfer, water insertion, proton release and O–O bond formation on sub-microsecond timescales.
Through archaeological excavation, morphological and proteomic taxonomic identification, mitochondrial DNA analysis and direct radiocarbon dating of human remains, a study reports the presence of Homo sapiens in Germany north of the Alps more than 45,000 years ago.
A computational model generates conformational ensembles of 28,058 intrinsically disordered proteins and regions (IDRs) in the human proteome and sheds light on the relationship between sequence, conformational properties and functions of IDRs.
Sea otters recolonizing an estuary in California indirectly reduce erosion by reducing burrowing crab abundance, suggesting that restoring predators could be a key mechanism to improve the stability of coastal wetlands and other ecosystems.
The E3 ligase SIFI is identified as a dedicated silencing factor of the integrated stress response, a finding that has implications for the development of therapeutics for neurodegenerative diseases caused by mitochondrial protein import stress.
We develop a proton-exchange membrane system that reduces CO2 to formic acid at a catalyst that is derived from waste lead–acid batteries and in which a lattice carbon activation mechanism contributes.
Analysis of data from the Born in Guangzhou Cohort Study comprising mainly of trios and mother–infant pairs reveals novel East Asian-specific genetic associations with maternal bile acid, gestational weight gain and infant cord blood traits.
Quantitative time-resolved microscopy analysis of SHR and SCR dynamics in single cells of living Arabidopsis roots shows that these transcription factors coordinate formative and proliferative cell divisions early in the cell cycle.
A study reports a combination of processing, optimization and low-damage deposition methods for the production of silicon heterojunction solar cells exhibiting flexibility and high performance.
7-Dehydrocholesterol (7-DHC) is a natural anti-ferroptotic metabolite and pharmacological manipulation of 7-DHC levels shows promise as a therapeutic strategy for cancer and ischaemia–reperfusion injury.
A mechanical design is developed for the fabrication of ultralong, fracture-free and perturbation-free semiconductor fibres to address the increasing demand for flexible and wearable optoelectronics.
Ultracold polyatomic molecules can be created by electroassociation in a degenerate Fermi gas of microwave-dressed polar molecules through a field-linked resonance.
Four future greenhouse gas emission scenarios for the global plastics system are investigated, with the lead scenario achieving net-zero emissions, and a series of technical, legal and economic interventions recommended.
