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Bile acids for diabetic cardiomyopathy
Diabetes can cause heart failure by a toxic accumulation of lipids in cardiac myocytes, which impairs their function. This work shows that stimulation of the bile acid receptor TGR5 limits fatty acid uptake into cardiac myocytes and prevents the development of diabetic cardiomyopathy.
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Systemic proteome adaptions to 7-day complete caloric restriction in humans
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Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota
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Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity
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Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue