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Blood glucose concentration measurement without finger pricking

Nature Metabolism volume 6, pages 615–616 (2024)Cite this article

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A new sensor that detects optoacoustic signals generated by mid-infrared light enables measurement of glucose concentration from intracutaneous tissue rich in blood. This technology does not rely on glucose measurements in interstitial fluid or blood sampling and might yield the next generation of non-invasive glucose-sensing devices for improved diabetes management.

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Fig. 1: Non-invasive in-blood glucose monitoring with DIROS.

References

  1. Tang, L., Chang, S. J., Chen, C. J. & Liu, J. T. Non-invasive blood glucose monitoring technology: a review.Sensors(Switzerland) 20, 6925 (2020). A review article on non-invasive glucose monitoring methods.

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  2. Aguirre, J. et al. Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy. Nat. Biomed. Eng. 1, 0068 (2017). This paper reports a technology for imaging microvasculature in the skin.

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This is a summary of: Uluç, N. et al. Non-invasive measurements of blood glucose levels by time-gating mid-infrared optoacoustic signals. Nat. Metab. https://doi.org/10.1038/s42255-024-01016-9 (2024).

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Blood glucose concentration measurement without finger pricking. Nat Metab 6, 615–616 (2024). https://doi.org/10.1038/s42255-024-01017-8

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