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Original Article
| Open AccessArginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury
- Esraa Shosha
- , Zhimin Xu
- & S Priya Narayanan
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Original Article
| Open AccessLithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV
- Ying Yang
- , Nandan Wu
- & Jing Zhuang
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Original Article
| Open AccessDe-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II
- A M Jacko
- , L Nan
- & Y Zhao
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Review
| Open AccessThe control of male fertility by spermatid-specific factors: searching for contraceptive targets from spermatozoon’s head to tail
- Su-Ren Chen
- , Aalia Batool
- & Yi-Xun Liu
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Original Article
| Open AccessCysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation
- Álvaro de Mingo
- , Estefanía de Gregorio
- & Montserrat Marí
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Original Article
| Open AccessDoxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death
- Chih-Yang Huang
- , Wei-Wen Kuo
- & Chih-Yang Huang
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Original Article
| Open AccessPAR2 regulates regeneration, transdifferentiation, and death
- Ron Piran
- , Seung-Hee Lee
- & Fred Levine
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Original Article
| Open AccessThe prosurvival protein BAG3: a new participant in vascular homeostasis
- Albino Carrizzo
- , Antonio Damato
- & Carmine Vecchione
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Original Article
| Open Access1, 25-dihydroxy-vitamin D3 with tumor necrosis factor-alpha protects against rheumatoid arthritis by promoting p53 acetylation-mediated apoptosis via Sirt1 in synoviocytes
- Xin Gu
- , Bingjie Gu
- & Jianliang Jin
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Original Article
| Open AccessLoss of Rictor with aging in osteoblasts promotes age-related bone loss
- Pinling Lai
- , Qiancheng Song
- & Xiaochun Bai
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Original Article
| Open AccessCnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes
- Mauro S Porcel de Peralta
- , Valeria S Mouguelar
- & Nora B Calcaterra
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Original Article
| Open AccessAttenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model
- Kit I Tong
- , Kazushige Ota
- & Hitoshi Okada
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Original Article
| Open AccessMesenchymal stem cells stimulate intestinal stem cells to repair radiation-induced intestinal injury
- Wei Gong
- , Mengzheng Guo
- & Qiang Liu
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News and Commentary
| Open AccessOxidative downmodulation of T cell-mediated cytotoxicity
- Guido H Wabnitz
- & Yvonne Samstag
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Original Article
| Open Access4-cholesten-3-one suppresses lung adenocarcinoma metastasis by regulating translocation of HMGB1, HIF1α and Caveolin-1
- Jinben Ma
- , Guobin Fu
- & Yibing Wang
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Original Article
| Open AccessThrombospondin-1 signaling through CD47 inhibits cell cycle progression and induces senescence in endothelial cells
- Qi Gao
- , Kexin Chen
- & Yong-Guang Yang
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Original Article
| Open AccessMiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a
- Yimeng Li
- , Ao Li
- & Huawei Li
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Original Article
| Open AccessRet is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model
- Anja Drinkut
- , Karsten Tillack
- & Edgar R Kramer
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Original Article
| Open AccessMCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL
- Ingela B Vikström
- , Anne Slomp
- & David M Tarlinton
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Original Article
| Open AccessLuteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model
- R Palombo
- , I Savini
- & A Terrinoni
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Original Article
| Open AccessAntitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey
- Christina L Zuch de Zafra
- , Avi Ashkenazi
- & Noël O Dybdal
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Original Article
| Open AccessFerroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
- S Ma
- , E S Henson
- & S B Gibson
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Original Article
| Open AccessActivation of salt-inducible kinase 2 promotes the viability of peritoneal mesothelial cells exposed to stress of peritoneal dialysis
- H-H Wang
- , C-Y Lin
- & C-J Chang
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Original Article
| Open AccessProton pump inhibitors protect mice from acute systemic inflammation and induce long-term cross-tolerance
- E Balza
- , P Piccioli
- & A Rubartelli
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Original Article
| Open AccessEndoplasmic reticulum stress eIF2α–ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney
- B Luo
- , Y Lin
- & Z Lin
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Original Article
| Open AccessContinuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy
- P Fan
- , Y Zhang
- & I Herr
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Original Article
| Open AccessImmune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model
- A Gomez-Cadena
- , C Urueña
- & S Fiorentino
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Original Article
| Open AccessEicosapentaenoic acid attenuates dexamethasome-induced apoptosis by inducing adaptive autophagy via GPR120 in murine bone marrow-derived mesenchymal stem cells
- B Gao
- , Y-H Han
- & Z-J Luo
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Original Article
| Open Access'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich’s ataxia'
- R Abeti
- , M H Parkinson
- & A Y Abramov
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Original Article
| Open AccessAllele-specific silencing of EEC p63 mutant R304W restores p63 transcriptional activity
- F Novelli
- , A M Lena
- & G Melino
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Original Article
| Open AccessKnockdown of linc-UFC1 suppresses proliferation and induces apoptosis of colorectal cancer
- T Yu
- , T-D Shan
- & Q-K Chen
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Original Article
| Open AccessChitohexaose protects against acetaminophen-induced hepatotoxicity in mice
- P K Barman
- , R Mukherjee
- & B Ravindran
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Original Article
| Open AccessIntraventricular injections of mesenchymal stem cells activate endogenous functional remyelination in a chronic demyelinating murine model
- P Cruz-Martinez
- , S González-Granero
- & S Martinez
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Original Article
| Open AccessSP6616 as a new Kv2.1 channel inhibitor efficiently promotes β-cell survival involving both PKC/Erk1/2 and CaM/PI3K/Akt signaling pathways
- T T Zhou
- , L L Quan
- & X Shen
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Original Article
| Open AccessDistal retinal ganglion cell axon transport loss and activation of p38 MAPK stress pathway following VEGF-A antagonism
- R Foxton
- , A Osborne
- & D T Shima
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Original Article
| Open AccessTranscription factor Six2 mediates the protection of GDNF on 6-OHDA lesioned dopaminergic neurons by regulating Smurf1 expression
- J Gao
- , X-y Kang
- & D-s Gao
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News and Commentary
| Open AccessNeuroprotective and neurorestorative potential of xenon
- J Lavaur
- , M Lemaire
- & P P Michel
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Original Article
| Open Accessβ-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy
- J Liu
- , Q X Li
- & F Yi
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Original Article
| Open AccessBIM mediates synergistic killing of B-cell acute lymphoblastic leukemia cells by BCL-2 and MEK inhibitors
- K Korfi
- , M Smith
- & R Marais
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Original Article
| Open AccessDihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway
- C Dou
- , N Ding
- & S Dong
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Original Article
| Open AccessFunctional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure
- A P Komarov
- , E A Komarova
- & A V Gudkov
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Original Article
| Open AccessFrom fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin polymerization inhibitor
- Y Mu
- , Y Liu
- & B Yan
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Original Article
| Open AccessNecroptosis in Niemann–Pick disease, type C1: a potential therapeutic target
- A Cougnoux
- , C Cluzeau
- & F D Porter
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Original Article
| Open AccessAdipogenic placenta-derived mesenchymal stem cells are not lineage restricted by withdrawing extrinsic factors: developing a novel visual angle in stem cell biology
- C Hu
- , H Cao
- & L Li
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Correspondence
| Open AccessRescue from early-onset hearing loss in a mouse model lacking the cyclin-dependent kinase inhibitor p19Ink4d
- Q Ma
- , M Grati
- & X Liu
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Original Article
| Open AccessWnt activation protects against neomycin-induced hair cell damage in the mouse cochlea
- L Liu
- , Y Chen
- & H Li
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Original Article
| Open AccessNeuregulin-1 attenuates cognitive function impairments in a transgenic mouse model of Alzheimer’s disease
- J Ryu
- , B-H Hong
- & H-S Kim
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Original Article
| Open AccessRole of apoptosis-related miRNAs in resveratrol-induced breast cancer cell death
- R Venkatadri
- , T Muni
- & N Azad
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