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| Open AccessIncreasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals
- Junjie Xu
- , Longbo Zheng
- & Xiujun Cai
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News and Commentary
| Open AccessSesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress
- Daniel Bodmer
- & Soledad Levano-Huaman
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Original Article
| Open AccessCardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway
- Shudong Wang
- , Yonggang Wang
- & Junlian Gu
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Original Article
| Open AccessDoxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells
- Sara Beji
- , Giuseppina Milano
- & Elisa Gambini
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Original Article
| Open AccessMiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5
- Bin Du
- , Xiao-meng Dai
- & Xue-song Yang
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Original Article
| Open AccessMice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration
- Michael D Burkitt
- , Jonathan M Williams
- & D Mark Pritchard
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Original Article
| Open AccessEpigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity
- Vikrant Borse
- , Raheem F H Al Aameri
- & Vickram Ramkumar
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Original Article
| Open AccessHIV integrase inhibitor, Elvitegravir, impairs RAG functions and inhibits V(D)J recombination
- Mayilaadumveettil Nishana
- , Namrata M Nilavar
- & Sathees C Raghavan
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Original Article
| Open AccessInhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain
- Yafeng Wang
- , Kai Zhou
- & Changlian Zhu
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Review
| Open AccessStatins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers
- Christian Henninger
- & Gerhard Fritz
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Original Article
| Open AccessDoxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death
- Chih-Yang Huang
- , Wei-Wen Kuo
- & Chih-Yang Huang
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Original Article
| Open AccessAttenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model
- Kit I Tong
- , Kazushige Ota
- & Hitoshi Okada
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Original Article
| Open AccessMiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a
- Yimeng Li
- , Ao Li
- & Huawei Li
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Original Article
| Open AccessAntitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey
- Christina L Zuch de Zafra
- , Avi Ashkenazi
- & Noël O Dybdal
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Original Article
| Open AccessEicosapentaenoic acid attenuates dexamethasome-induced apoptosis by inducing adaptive autophagy via GPR120 in murine bone marrow-derived mesenchymal stem cells
- B Gao
- , Y-H Han
- & Z-J Luo
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Original Article
| Open AccessChitohexaose protects against acetaminophen-induced hepatotoxicity in mice
- P K Barman
- , R Mukherjee
- & B Ravindran
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Original Article
| Open AccessWnt activation protects against neomycin-induced hair cell damage in the mouse cochlea
- L Liu
- , Y Chen
- & H Li
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News and Commentary
| Open AccessHistamine: a potential cytoprotective agent to improve cancer therapy?
- D J Martinel Lamas
- , M B Nicoud
- & V A Medina
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Original Article
| Open AccessLoss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors
- S Levano
- & D Bodmer
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News and Commentary
| Open AccessPreventing ototoxic hearing loss by inhibiting histone deacetylases
- W S Layman
- & J Zuo
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Original Article
| Open AccessXBP1 mitigates aminoglycoside-induced endoplasmic reticulum stress and neuronal cell death
- N Oishi
- , S Duscha
- & J Schacht
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Original Article
| Open AccessCellular oxidative stress response mediates radiosensitivity in Fus1-deficient mice
- E M Yazlovitskaya
- , P A Voziyan
- & A V Ivanova
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Editorial
| Open AccessThe 1000th publication features protection of normal cells during chemotherapy: a land mark for Cell Death & Disease
- Y Shi
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Original Article
| Open AccessThe traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression
- M S Becker
- , P Schmezer
- & M Li-Weber
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Original Article
| Open AccessRole of CFTR in oxidative stress and suicidal death of renal cells during cisplatin-induced nephrotoxicity
- I Rubera
- , C Duranton
- & M Tauc
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Original Article
| Open AccessMulti-therapeutic effects of human adipose-derived mesenchymal stem cells on radiation-induced intestinal injury
- P Chang
- , Y Qu
- & X Jin
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Original Article
| Open AccessMetabolic effects of TiO2 nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytes
- P Tucci
- , G Porta
- & A Willis
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Original Article
| Open AccessApoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence
- C Drullion
- , C Trégoat
- & J-M Pasquet
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Original Article
| Open AccessApoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts
- S Ghavami
- , B Yeganeh
- & A J Halayko
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Original Article
| Open AccessCelastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32
- S P Francis
- , I I Kramarenko
- & L L Cunningham
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Original Article
| Open AccessInhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity
- J Huelsenbeck
- , C Henninger
- & G Fritz
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Original Article
| Open AccessShort interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation
- T Kaur
- , D Mukherjea
- & V Ramkumar
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Original Article
| Open AccessRole of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage
- A Badmann
- , A Keough
- & N Corazza
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Original Article
| Open AccessSalinomycin induces calpain and cytochrome c-mediated neuronal cell death
- W Boehmerle
- & M Endres