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Specific detection of soluble EphA2 fragments in blood as a new biomarker for pancreatic cancer
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Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib
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Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossification retardation and its molecular mechanism in female fetal rats
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iASPP facilitates tumor growth by promoting mTOR-dependent autophagy in human non-small-cell lung cancer
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Increasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals
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Current progress in the derivation and therapeutic application of neural stem cells
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RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization
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p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure
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Transplanted human p75-positive stem Leydig cells replace disrupted Leydig cells for testosterone production
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Sesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress
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Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death
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Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage
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Tat-protein disulfide-isomerase A3: a possible candidate for preventing ischemic damage in the spinal cord
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NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy
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LRP6 is identified as a potential prognostic marker for oral squamous cell carcinoma via MALDI-IMS
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Tailored therapy guided by multichannel intraluminal impedance pH monitoring for refractory non-erosive reflux disease
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Cardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway
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Apatinib promotes autophagy and apoptosis through VEGFR2/STAT3/BCL-2 signaling in osteosarcoma
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Role of PD-L1 expression as a biomarker for GEP neuroendocrine neoplasm grading
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Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells
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Original Article
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The erythropoietin-derived peptide MK-X and erythropoietin have neuroprotective effects against ischemic brain damage
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Identification and characterization of a new source of adult human neural progenitors
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Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer
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MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5
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Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens
- Álvaro F Fernández
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Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration
- Michael D Burkitt
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Original Article
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Killing two birds with one stone: dual blockade of integrin and FGF signaling through targeting syndecan-4 in postoperative capsular opacification
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An autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells
- Deyong Jia
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Original Article
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Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity
- Vikrant Borse
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Original Article
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Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis
- Gaku Tsuji
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BAG3 promotes stem cell-like phenotype in breast cancer by upregulation of CXCR4 via interaction with its transcript
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Original Article
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Role of peroxiredoxin2 downregulation in recurrent miscarriage through regulation of trophoblast proliferation and apoptosis
- Fan Wu
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Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu
- Yvonne Huber
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AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer
- Dandan Huang
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RETRACTED ARTICLE:LISPRO mitigates β-amyloid and associated pathologies in Alzheimer’s mice
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Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study
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Simvastatin treatment boosts benefits of apoptotic cell infusion in murine lung fibrosis
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Upconversion nanoparticle-mediated photodynamic therapy induces autophagy and cholesterol efflux of macrophage-derived foam cells via ROS generation
- Xiaobo B Han
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Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death
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Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target
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HIV integrase inhibitor, Elvitegravir, impairs RAG functions and inhibits V(D)J recombination
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Cystatin C as a potential therapeutic mediator against Parkinson’s disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units
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Restricting the induction of NGF in ovarian stroma engenders selective follicular activation through the mTOR signaling pathway
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Hepatocyte polyploidization and its association with pathophysiological processes
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Original Article
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Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ–p53–p21 signaling pathway
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Original Article
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Cisplatin-enriching cancer stem cells confer multidrug resistance in non-small cell lung cancer via enhancing TRIB1/HDAC activity
- Lihui Wang
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Original Article
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Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer
- Jiaying Shen
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Original Article
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Erythropoietin protects against rhabdomyolysis-induced acute kidney injury by modulating macrophage polarization
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Metformin ameliorates arsenic trioxide hepatotoxicity via inhibiting mitochondrial complex I