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Original Article
| Open AccessPhosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib
- Cristina Quintavalle
- , Sravanth Kumar Hindupur
- & Matthias Sebastian Matter
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News and Commentary
| Open AccessEmergence of aspirin as a promising chemopreventive and chemotherapeutic agent for liver cancer
- Hongping Xia
- & Kam M Hui
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Original Article
| Open AccessIncreasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals
- Junjie Xu
- , Longbo Zheng
- & Xiujun Cai
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Review
| Open AccessCurrent progress in the derivation and therapeutic application of neural stem cells
- Yuewen Tang
- , Pei Yu
- & Lin Cheng
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Original Article
| Open AccessTransplanted human p75-positive stem Leydig cells replace disrupted Leydig cells for testosterone production
- Min Zhang
- , Jiancheng Wang
- & Andy Peng Xiang
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News and Commentary
| Open AccessSesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress
- Daniel Bodmer
- & Soledad Levano-Huaman
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Original Article
| Open AccessTargeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death
- Karoline Johanna Habermann
- , Leon Grünewald
- & Simone Fulda
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Original Article
| Open AccessTat-protein disulfide-isomerase A3: a possible candidate for preventing ischemic damage in the spinal cord
- Dae Young Yoo
- , Su Bin Cho
- & Seung Myung Moon
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Original Article
| Open AccessNDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy
- Hongsheng Wang
- , Wen Li
- & Yingqi Hua
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Original Article
| Open AccessTailored therapy guided by multichannel intraluminal impedance pH monitoring for refractory non-erosive reflux disease
- Nunzio Ranaldo
- , Giuseppe Losurdo
- & Alfredo Di Leo
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Original Article
| Open AccessCardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway
- Shudong Wang
- , Yonggang Wang
- & Junlian Gu
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Original Article
| Open AccessApatinib promotes autophagy and apoptosis through VEGFR2/STAT3/BCL-2 signaling in osteosarcoma
- Kuisheng Liu
- , Tingting Ren
- & Wei Guo
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Original Article
| Open AccessDoxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells
- Sara Beji
- , Giuseppina Milano
- & Elisa Gambini
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Original Article
| Open AccessThe erythropoietin-derived peptide MK-X and erythropoietin have neuroprotective effects against ischemic brain damage
- Seung-Jun Yoo
- , Bongki Cho
- & Cheil Moon
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Original Article
| Open AccessIdentification and characterization of a new source of adult human neural progenitors
- Jinan Behnan
- , Biljana Stangeland
- & Wayne Murrell
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Original Article
| Open AccessMiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5
- Bin Du
- , Xiao-meng Dai
- & Xue-song Yang
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Original Article
| Open AccessMice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration
- Michael D Burkitt
- , Jonathan M Williams
- & D Mark Pritchard
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Original Article
| Open AccessKilling two birds with one stone: dual blockade of integrin and FGF signaling through targeting syndecan-4 in postoperative capsular opacification
- Yingyan Qin
- , Yi Zhu
- & Mingxing Wu
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Original Article
| Open AccessAn autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells
- Deyong Jia
- , Li Li
- & Lisheng Wang
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Original Article
| Open AccessEpigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity
- Vikrant Borse
- , Raheem F H Al Aameri
- & Vickram Ramkumar
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Original Article
| Open AccessAryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis
- Gaku Tsuji
- , Akiko Hashimoto-Hachiya
- & Masutaka Furue
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Original Article
| Open AccessAQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer
- Dandan Huang
- , Xingzhi Feng
- & Zihuan Yang
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Original Article
| Open AccessSimvastatin treatment boosts benefits of apoptotic cell infusion in murine lung fibrosis
- Ye-JI Lee
- , Meung-Joo Kim
- & Jihee Lee Kang
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Original Article
| Open AccessPrecision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study
- Rahul Agarwal
- , Yuan Cao
- & Gianluigi Giannelli
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Original Article
| Open AccessUpconversion nanoparticle-mediated photodynamic therapy induces autophagy and cholesterol efflux of macrophage-derived foam cells via ROS generation
- Xiaobo B Han
- , Hongxia X Li
- & Liming M Yang
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Original Article
| Open AccessHuman cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death
- Emarndeena H Cheteh
- , Martin Augsten
- & Klas G Wiman
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Original Article
| Open AccessPromoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target
- Ping Xie
- , Jun-Ping Yang
- & Chao-Nan Qian
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Original Article
| Open AccessHIV integrase inhibitor, Elvitegravir, impairs RAG functions and inhibits V(D)J recombination
- Mayilaadumveettil Nishana
- , Namrata M Nilavar
- & Sathees C Raghavan
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Original Article
| Open AccessCystatin C as a potential therapeutic mediator against Parkinson’s disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units
- Jing Zou
- , Zhaoyu Chen
- & Qing Wang
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Original Article
| Open AccessRestricting the induction of NGF in ovarian stroma engenders selective follicular activation through the mTOR signaling pathway
- Yuanlin He
- , Xiaoxu Peng
- & Jing Li
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Original Article
| Open AccessCisplatin-enriching cancer stem cells confer multidrug resistance in non-small cell lung cancer via enhancing TRIB1/HDAC activity
- Lihui Wang
- , Xing Liu
- & Chunfu Wu
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Original Article
| Open AccessErythropoietin protects against rhabdomyolysis-induced acute kidney injury by modulating macrophage polarization
- Shuo Wang
- , Chao Zhang
- & Tongyu Zhu
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Original Article
| Open AccessInhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain
- Yafeng Wang
- , Kai Zhou
- & Changlian Zhu
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Original Article
| Open AccessGanetespib synergizes with cyclophosphamide to improve survival of mice with autochthonous tumors in a mutant p53-dependent manner
- Evguenia M Alexandrova
- , Sulan Xu
- & Ute M Moll
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Original Article
| Open AccessThioridazine enhances sensitivity to carboplatin in human head and neck cancer cells through downregulation of c-FLIP and Mcl-1 expression
- Seung Un Seo
- , Hyuk Ki Cho
- & Taeg Kyu Kwon
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Original Article
| Open AccessNLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages
- Yan-gang Liu
- , Ji-kuai Chen
- & Guo-cai Lu
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Original Article
| Open AccessIncrease in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury
- Zelin Chen
- , Xin Wang
- & Chunmeng Shi
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Review
| Open AccessStatins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers
- Christian Henninger
- & Gerhard Fritz
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Original Article
| Open AccessBerberine-sonodynamic therapy induces autophagy and lipid unloading in macrophage
- Jiayuan Y Kou
- , Ying Li
- & Liming M Yang
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Original Article
| Open AccessHuman adipose stem cell differentiation is highly affected by cancer cells both in vitro and in vivo: implication for autologous fat grafting
- Francesca Paino
- , Marcella La Noce
- & Virginia Tirino
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Original Article
| Open AccessHIF-2α and Oct4 have synergistic effects on survival and myocardial repair of very small embryonic-like mesenchymal stem cells in infarcted hearts
- Shaoheng Zhang
- , Lan Zhao
- & Xin Pan
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Original Article
| Open AccessHuman umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis
- Tae-Hoon Shin
- , Hyung-Sik Kim
- & Kyung-Sun Kang
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Original Article
| Open AccessDual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC
- Jae-Seon Lee
- , Joon H Kang
- & Soo-Youl Kim
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Original Article
| Open AccessHyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation
- Madhulika Tripathi
- , Cheng Wu Zhang
- & Paul Michael Yen
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Original Article
| Open AccessCombined nifuroxazide and SAT05f therapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation
- Huijie Jia
- , Tiesuo Zhao
- & Kailin Xu
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Original Article
| Open AccessInflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
- Xiao-Ming Meng
- , Shuang Wang
- & Hui-Yao Lan
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Original Article
| Open AccessTherapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer’s disease models
- Stuart A Lipton
- , Tayebeh Rezaie
- & Nobuki Nakanishi
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Original Article
| Open Access1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis
- Chunyan Wei
- , Jie Mei
- & Xiaoyong Zhu
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Original Article
| Open AccessA mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC
- Nicole A Seebacher
- , Des R Richardson
- & Patric J Jansson
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