Featured
-
-
Article
| Open AccessBerberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes
- Shuna Sun
- , Xiaojie Zhang
- & Yongxin Zou
-
Article
| Open AccessLoss of the androgen receptor suppresses intrarenal calcium oxalate crystals deposition via altering macrophage recruitment/M2 polarization with change of the miR-185-5p/CSF-1 signals
- Wei Zhu
- , Zhijian Zhao
- & Chawnshang Chang
-
Meeting Report
| Open Access6th International Multithematic Scientific Bio-Medical Congress (IMBMC), Nicosia, Cyprus, 2018
- Anthony Lisacek-Kiosoglous
- , Andrew Georgiou
- & Ioannis Patrikios
-
Article
| Open AccessT-cell senescence contributes to abnormal glucose homeostasis in humans and mice
- Hyon-Seung Yi
- , So Yeon Kim
- & Bon Jeong Ku
-
Article
| Open AccessSquaramide-based synthetic chloride transporters activate TFEB but block autophagic flux
- Shaoyi Zhang
- , Yan Wang
- & Guido Kroemer
-
Article
| Open AccessAKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration
- Haoliang Huang
- , Linqing Miao
- & Yang Hu
-
Article
| Open AccessOrganoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases
- Ludovica Grassi
- , Romina Alfonsi
- & Désirée Bonci
-
Article
| Open AccessDexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis
- Yi-Bing Sun
- , Hailin Zhao
- & Daqing Ma
-
Article
| Open AccessH19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis
- Li Zhang
- , Zhihong Yang
- & Jianguo Wu
-
-
Article
| Open AccessApplying an innovative biodegradable self-assembly nanomicelles to deliver α-mangostin for improving anti-melanoma activity
- Shuping Yang
- , Xiang Gao
- & Yongmei Xie
-
Article
| Open AccessMiR-210-3p protects endometriotic cells from oxidative stress-induced cell cycle arrest by targeting BARD1
- Yongdong Dai
- , Xiang Lin
- & Songying Zhang
-
Article
| Open AccessTargeting autophagy potentiates antitumor activity of Met-TKIs against Met-amplified gastric cancer
- Xiaoting Lin
- , Zhi Peng
- & Lin Shen
-
Article
| Open AccesssPIF promotes myoblast differentiation and utrophin expression while inhibiting fibrosis in Duchenne muscular dystrophy via the H19/miR-675/let-7 and miR-21 pathways
- Daria Morgoulis
- , Peter Berenstein
- & Chaya Brodie
-
Article
| Open AccessCYTL1 regulates bone homeostasis in mice by modulating osteogenesis of mesenchymal stem cells and osteoclastogenesis of bone marrow-derived macrophages
- Youngnim Shin
- , Yoonkyung Won
- & Jang-Soo Chun
-
Review Article
| Open AccessMolecular mechanisms in the pathogenesis of N-nitrosodimethylamine induced hepatic fibrosis
- Joseph George
- , Mutsumi Tsuchishima
- & Mikihiro Tsutsumi
-
Article
| Open AccessSanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy
- Dan Hao
- , Xiang Wen
- & Xian Jiang
-
Article
| Open AccessLack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia–ischemia
- Juan Rodriguez
- , Yaodong Zhang
- & Changlian Zhu
-
Article
| Open AccessTargeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis
- Marta Varela-Eirín
- , Adrián Varela-Vázquez
- & María D. Mayán
-
Article
| Open AccessLong non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy
- Meng Wang
- , Dong Han
- & Xishan Wang
-
Article
| Open AccessThe SGK3-triggered ubiquitin–proteasome degradation of podocalyxin (PC) and ezrin in podocytes was associated with the stability of the PC/ezrin complex
- Ya-Pei Yuan
- , Hong Zhao
- & Li-Jun Yao
-
Article
| Open AccessPINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury
- Ying Wang
- , Chengyuan Tang
- & Zheng Dong
-
Article
| Open AccessSrc-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activation
- I-Che Chung
- , Sheng-Ning Yuan
- & Lih-Chyang Chen
-
Review
| Open AccessSkin-derived stem cells as a source of primordial germ cell- and oocyte-like cells
- Wei Ge
- , Shun-Feng Cheng
- & Wei Shen
-
Original Article
| Open AccessAnti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis
- Michaela Ohmer
- , Arnim Weber
- & Georg Häcker
-
Original Article
| Open AccessPGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes
- B Anta
- , A Pérez-Rodríguez
- & J M Rojas-Cabañeros
-
Original Article
| Open AccessExtracellular DNA traps released by acute promyelocytic leukemia cells through autophagy
- R Ma
- , T Li
- & J Shi
-
News and Commentary
| Open AccessProspects of adjuvant RANKL inhibition in breast cancer?
- T D Rachner
- , P Wimberger
- & L C Hofbauer
-
Original Article
| Open AccessPeroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation
- L Li
- , T Li
- & Y Lou
-
Original Article
| Open AccessImpact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice
- M J Herold
- , R Stuchbery
- & P Bouillet
-
Original Article
| Open AccessAdiponectin deficiency exacerbates age-related hearing impairment
- T Tanigawa
- , R Shibata
- & T Murohara
-
Original Article
| Open AccessIdentification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscle
- A Uezumi
- , S Fukada
- & K Tsuchida
-
Original Article
| Open AccessPreclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009
- I-N Hsieh
- , J-P Liou
- & C-R Yang
-
News and Commentary
| Open AccessTaking into account the gender issue in cell death studies
- E Ortona
- , P Matarrese
- & W Malorni
-
Original Article
| Open AccessDRUGSURV: a resource for repositioning of approved and experimental drugs in oncology based on patient survival information
- I Amelio
- , M Gostev
- & A V Antonov
-
Original Article
| Open AccessThe use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their function
- L K J Stadler
- , D C Tomlinson
- & P Ko Ferrigno
-
Original Article
| Open AccessChloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity
- M T Harper
- & A W Poole
-
Review
| Open AccessCyclophilin A: a key player for human disease
- P Nigro
- , G Pompilio
- & M C Capogrossi
-
Original Article
| Open AccessThe purinergic P2Y14 receptor axis is a molecular determinant for organism survival under in utero radiation toxicity
- S H Kook
- , J S Cho
- & B-C Lee
-
Original Article
| Open AccessApoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis
- M Oropesa-Ávila
- , A Fernández-Vega
- & J A Sánchez-Alcázar
-
Original Article
| Open AccessNecrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
- N Takahashi
- , L Duprez
- & P Vandenabeele
-
Original Article
| Open AccessTargeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor
- D Chauvier
- , S Renolleau
- & E Jacotot
-
Original Article
| Open AccessThe organotelluride catalyst LAB027 prevents colon cancer growth in the mice
- R Coriat
- , W Marut
- & F Batteux
-
Original Article
| Open AccessCarnitine reduces the lipoperoxidative damage of the membrane and apoptosis after induction of cell stress in experimental glaucoma
- N Calandrella
- , C De Seta
- & G Risuleo
-
Meeting Report
| Open AccessCell death: physiopathological and therapeutic implications
- M Lulli
- , F Di Gesualdo
- & S Capaccioli