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Modeling acute myocardial infarction and cardiac fibrosis using human induced pluripotent stem cell-derived multi-cellular heart organoids
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Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes
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Fatty acid-binding protein 5 is a functional biomarker and indicator of ferroptosis in cerebral hypoxia
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Protective effect of increased O-GlcNAc cycling against 6-OHDA induced Parkinson’s disease pathology
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Hepatic Sirt6 activation abrogates acute liver failure
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Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment
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Caspase 8 deletion causes infection/inflammation-induced bone marrow failure and MDS-like disease in mice
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Cancer-associated fibroblasts secrete FGF5 to inhibit ferroptosis to decrease cisplatin sensitivity in nasopharyngeal carcinoma through binding to FGFR2
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Meeting Report
| Open Access11th international multithematic scientific biomedical congress (IMBMC), Nicosia, Cyprus, 2023
- Panayiota Christodoulou
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Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications
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ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance
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Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review
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FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation
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The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons
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Endothelial DR6 in blood-brain barrier malfunction in Alzheimer’s disease
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PDZK1 suppresses TNBC development and sensitizes TNBC cells to erlotinib via the EGFR pathway
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RUVBL1 ubiquitination by DTL promotes RUVBL1/2-β-catenin-mediated transcriptional regulation of NHEJ pathway and enhances radiation resistance in breast cancer
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Research progress of post-acute sequelae after SARS-CoV-2 infection
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Dietary factors and their influence on immunotherapy strategies in oncology: a comprehensive review
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The broad impact of cell death genes on the human disease phenome
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Transglutaminase 3 regulates cutaneous squamous carcinoma differentiation and inhibits progression via PI3K-AKT signaling pathway-mediated Keratin 14 degradation
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Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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Ovarian tumor cell-derived JAGGED2 promotes omental metastasis through stimulating the Notch signaling pathway in the mesothelial cells
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Orthogonal analysis of mitochondrial function in Parkinson’s disease patients
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Targeting RCC1 to block the human soft-tissue sarcoma by disrupting nucleo-cytoplasmic trafficking of Skp2
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TRIB3 promotes the progression of renal cell carcinoma by upregulating the lipid droplet-associated protein PLIN2
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AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis
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The 10th Barossa meeting: Cell Signalling to Cancer Medicine
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The role of RNA-modifying proteins in renal cell carcinoma
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Disrupting pro-survival and inflammatory pathways with dimethyl fumarate sensitizes chronic lymphocytic leukemia to cell death
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TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer
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Hypoxia-induced miR-5100 promotes exosome-mediated activation of cancer-associated fibroblasts and metastasis of head and neck squamous cell carcinoma
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TAB182 regulates glycolytic metabolism by controlling LDHA transcription to impact tumor radiosensitivity
- Shi Chen
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Single-cell RNA-seq reveals keratinocyte and fibroblast heterogeneity and their crosstalk via epithelial-mesenchymal transition in psoriasis
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GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas
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A first-in-class TIMM44 blocker inhibits bladder cancer cell growth
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Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice
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Isoform alterations in the ubiquitination machinery impacting gastrointestinal malignancies
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The RNA m6A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer
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Synergistic antitumor activity between HER2 antibody-drug conjugate and chemotherapy for treating advanced colorectal cancer
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Gasdermin E promotes translocation of p65 and c-jun into nucleus in keratinocytes for progression of psoriatic skin inflammation
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TRIB3 promotes malignancy of head and neck squamous cell carcinoma via inhibiting ferroptosis
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mTOR pathway occupies a central role in the emergence of latent cancer cells
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KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC
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SPOP point mutations regulate substrate preference and affect its function
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Concurrent inhibition of pBADS99 synergistically improves MEK inhibitor efficacy in KRASG12D-mutant pancreatic ductal adenocarcinoma
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miR-184 represses β-catenin and behaves as a skin tumor suppressor
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Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress
- Silvia Cardarelli
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Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence
- Viola Kluge
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Modulating extracellular matrix stiffness: a strategic approach to boost cancer immunotherapy