Featured
-
-
Article
| Open AccessRoseotoxin B alleviates cholestatic liver fibrosis through inhibiting PDGF-B/PDGFR-β pathway in hepatic stellate cells
- Xingqi Wang
- , Yuzhi Gao
- & Ruiqin Yao
-
Article
| Open AccessIntestinal vitamin D receptor knockout protects from oxazolone-induced colitis
- Yongyan Shi
- , Ziyun Liu
- & Tianjing Liu
-
Article
| Open AccessEndogenously produced LG3/4/5-peptide protects testes against toxicant-induced injury
- Linxi Li
- , Baiping Mao
- & C. Yan Cheng
-
Article
| Open AccessCharacterization of a new small-molecule inhibitor of HDAC6 in glioblastoma
- Jaione Auzmendi-Iriarte
- , Ander Saenz-Antoñanzas
- & Ander Matheu
-
Article
| Open AccessThe lncRNA RUNX1-IT1 regulates C-FOS transcription by interacting with RUNX1 in the process of pancreatic cancer proliferation, migration and invasion
- Songsong Liu
- , Junfeng Zhang
- & Huaizhi Wang
-
Article
| Open AccessThe interaction of interleukin-8 and PTEN inactivation promotes the malignant progression of head and neck squamous cell carcinoma via the STAT3 pathway
- Qiaoshi Xu
- , Hailong Ma
- & Xi Yang
-
Article
| Open AccessSynergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells
- Xiaogang Chen
- , Dan Zhang
- & Shuzhen Wang
-
Article
| Open AccessActivation of adenosine A3 receptor protects retinal ganglion cells from degeneration induced by ocular hypertension
- Raquel Boia
- , Manuel Salinas-Navarro
- & Ana Raquel Santiago
-
Article
| Open AccessLoss of Spry1 reduces growth of BRAFV600-mutant cutaneous melanoma and improves response to targeted therapy
- Barbara Montico
- , Francesca Colizzi
- & Elisabetta Fratta
-
Article
| Open Accessβ-arrestin2 deficiency protects against hepatic fibrosis in mice and prevents synthesis of extracellular matrix
- Wu-Yi Sun
- , Yuan-Jing Gu
- & Wei Wei
-
Article
| Open AccessCaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts
- Hong-Ting Lu
- , Ren-Qian Feng
- & Jun Ren
-
Article
| Open AccessNeutrophils undergo switch of apoptosis to NETosis during murine fatty liver injury via S1P receptor 2 signaling
- Xinhao Zhao
- , Le Yang
- & Liying Li
-
-
Article
| Open AccessLong noncoding RNA lncARSR confers resistance to Adriamycin and promotes osteosarcoma progression
- Peng Shen
- & Yanfeng Cheng
-
Perspective
| Open AccessExploiting immune-dependent effects of microtubule-targeting agents to improve efficacy and tolerability of cancer treatment
- Angela Flavia Serpico
- , Roberta Visconti
- & Domenico Grieco
-
Article
| Open Accesscirc5615 functions as a ceRNA to promote colorectal cancer progression by upregulating TNKS
- Zhifei Ma
- , Chencheng Han
- & Liu Yang
-
Article
| Open AccessFTSJ1 regulates tRNA 2ʹ-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression
- Qihan He
- , Lin Yang
- & Rihong Zhai
-
Article
| Open AccessLGR5+ epithelial tumor stem-like cells generate a 3D-organoid model for ameloblastoma
- Ting-Han Chang
- , Rabie M. Shanti
- & Anh D. Le
-
Article
| Open AccessExosomes derived from mesenchymal stem cells repair a Parkinson’s disease model by inducing autophagy
- Hong-Xu Chen
- , Fu-Chao Liang
- & Sheng-Jun An
-
Article
| Open AccessMicroRNA-4476 promotes glioma progression through a miR-4476/APC/β-catenin/c-Jun positive feedback loop
- Jie Lin
- , Shengfeng Ding
- & Xian Zhang
-
Article
| Open AccessTumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C
- Anna Mary Steitz
- , Alina Steffes
- & Silke Reinartz
-
Comment
| Open AccessThe p53/MDM2/MDMX-targeted therapies—a clinical synopsis
- Liren Jiang
- & Joanna Zawacka-Pankau
-
Article
| Open AccessCaveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor–stroma interactions
- Julia Ketteler
- , Alina Wittka
- & Diana Klein
-
Article
| Open AccessImbalance in mitochondrial dynamics induced by low PGC-1α expression contributes to hepatocyte EMT and liver fibrosis
- Linzhong Zhang
- , Yanghao Zhang
- & Xiuying Zhang
-
Article
| Open AccessPan-cancer analysis reveals synergistic effects of CDK4/6i and PARPi combination treatment in RB-proficient and RB-deficient breast cancer cells
- Songyu Li
- , Yixiang Zhang
- & Qing-kai Yang
-
Article
| Open AccessCross organelle stress response disruption promotes gentamicin-induced proteotoxicity
- Chinaemere Igwebuike
- , Julia Yaglom
- & Steven C. Borkan
-
Article
| Open AccessExosome-transmitted lncRNA UFC1 promotes non-small-cell lung cancer progression by EZH2-mediated epigenetic silencing of PTEN expression
- Xueyan Zang
- , Jianmei Gu
- & Xu Zhang
-
Article
| Open AccessMyofibroblast induces hepatocyte-to-ductal metaplasia via laminin–ɑvβ6 integrin in liver fibrosis
- Ting Xu
- , Zhiwen Lu
- & Yuhu Song
-
Article
| Open AccessPlasminogen is a master regulator and a potential drug candidate for the healing of radiation wounds
- Mahsa Fallah
- , Emil Viklund
- & Tor Ny
-
Article
| Open AccessMYC-regulated pseudogene HMGA1P6 promotes ovarian cancer malignancy via augmenting the oncogenic HMGA1/2
- Xiaoxue Tian
- , Jianping Song
- & Zhaojian Liu
-
Article
| Open AccessMutations in the coat complex II component SEC23B promote colorectal cancer metastasis
- Chunyuan Yang
- , Nan Chen
- & Yuxin Yin
-
Article
| Open AccessMicrocystin-LR ameliorates pulmonary fibrosis via modulating CD206+ M2-like macrophage polarization
- Jie Wang
- , Lizhi Xu
- & Yaping Wang
-
Article
| Open AccessTargeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo
- Guifang Du
- , Jing Wang
- & Yinying Lu
-
Article
| Open AccessMetformin reduces HGF-induced resistance to alectinib via the inhibition of Gab1
- Hengyi Chen
- , Caiyu Lin
- & Yong He
-
Review Article
| Open AccessErythropoietin and its derivatives: from tissue protection to immune regulation
- Bo Peng
- , Gangcheng Kong
- & Yingzi Ming
-
Article
| Open AccessThe concentration of tumor necrosis factor-α determines its protective or damaging effect on liver injury by regulating Yap activity
- Shanmin Zhao
- , Jinghua Jiang
- & Lixin Wei
-
Article
| Open AccessEffects of thrombospondin-4 on pro-inflammatory phenotype differentiation and apoptosis in macrophages
- Mohammed Tanjimur Rahman
- , Santoshi Muppala
- & Olga Stenina-Adognravi
-
Article
| Open AccessIntravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy
- Mrinmoy Das
- , Anupama Karnam
- & Jagadeesh Bayry
-
Article
| Open AccessCharacterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer
- Jing Ma
- , Mohanraj Ramachandran
- & Magnus Essand
-
Article
| Open AccessCross-talk between autophagy and apoptosis regulates testicular injury/recovery induced by cadmium via PI3K with mTOR-independent pathway
- Mei Wang
- , Xiao-fei Wang
- & Ping Su
-
Article
| Open AccessImprovement of epidermal covering on AEC patients with severe skin erosions by PRIMA-1MET/APR-246
- Edith Aberdam
- , Lauriane N. Roux
- & Smail Hadj-Rabia
-
Article
| Open AccessCircular RNA circ_001621 promotes osteosarcoma cells proliferation and migration by sponging miR-578 and regulating VEGF expression
- Xianglu Ji
- , Liping Shan
- & Ming He
-
Article
| Open AccessIdentification of a transient state during the acquisition of temozolomide resistance in glioblastoma
- Marion Rabé
- , Solenne Dumont
- & François M. Vallette
-
Article
| Open AccessOligodendrocyte precursor cells transplantation protects blood–brain barrier in a mouse model of brain ischemia via Wnt/β-catenin signaling
- Liping Wang
- , Jieli Geng
- & Guo-Yuan Yang
-
Article
| Open AccessAcyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator
- Nikolaos Charmpilas
- , Christoph Ruckenstuhl
- & Guido Kroemer
-
Article
| Open AccessNovel HDAC inhibitor Chidamide synergizes with Rituximab to inhibit diffuse large B-cell lymphoma tumour growth by upregulating CD20
- Xu-Wen Guan
- , Hua-Qing Wang
- & Feng-Ting Liu
-
Article
| Open AccessBCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cells
- Sehar Afreen
- , Sheila Bohler
- & Miriam Erlacher
-
Article
| Open AccessGSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ
- Sonia Ciotti
- , Luca Iuliano
- & Claudio Brancolini
-
Article
| Open AccessTLR5: A prognostic and monitoring indicator for triple-negative breast cancer
- Dai Shi
- , Shanshan Zhao
- & Guihua Hou