Volume 2 Issue 3, March 2007

Overlaid crystal structures of hepatitis B virus with (red, PDB file 2G34) and without (blue, 2G33) a small molecule that enhances assembly and distorts capsid structure: in the presence of HAP1, fivefolds are at greater radius and quasi-sixfolds are flattened. Image courtesy of Cristina Bourne, one of the authors of the protocol by Zlotnick et al.