Focus
Focus on stress
- Focus issue:
- October 2015 Volume 18, No 10
Stress is something we all experience. While stress serves an important purpose in maintaining health, prolonged or severe stress can be harmful, particularly to the central nervous system. Neuroscience research has provided insight into how stress affects brain function and behavior, and how it can contribute to the development of psychiatric diseases. Recent technological developments allowing for greater understanding of the circuits involved in the stress response and the genetic and epigenetic mechanisms underlying the effects of stress have accelerated research in this field, with the potential for translational benefits. Nature Neuroscience presents a special issue focused on stress via a series of reviews and perspectives written by leaders in the field.
Editorial
Focus on stress
Focus on stress- p1343
doi:10.1038/nn.4127
We present a special issue focusing on recent advances in the understanding of the effects of stress on the nervous system and behavior, as well as the role of the nervous system in regulating responses to stress.
Commentary
Focus on stress
Stress and the brain: individual variability and the inverted-U- pp1344 - 1346
Robert M Sapolsky
doi:10.1038/nn.4109
Abstract - | Full Text - Stress and the brain: individual variability and the inverted-U | PDF (560 KB) - Stress and the brain: individual variability and the inverted-U
Perspective
Focus on stress
Finding translation in stress research- pp1347 - 1352
Ahmad R Hariri and Andrew Holmes
doi:10.1038/nn.4111
Full Text - Optogenetics: 10 years after ChR2 in neurons—views from the community | PDF (1,100 KB) - Optogenetics: 10 years after ChR2 in neurons—views from the community
Reviews
Focus on stress
Mechanisms of stress in the brain- pp1353 - 1363
Bruce S McEwen, Nicole P Bowles, Jason D Gray, Matthew N Hill, Richard G Hunter, Ilia N Karatsoreos and Carla Nasca
doi:10.1038/nn.4086
Abstract - | Full Text - Mechanisms of stress in the brain | PDF (1,682 KB) - Mechanisms of stress in the brain
Focus on stress
Neighborhood matters: divergent patterns of stress-induced plasticity across the brain- pp1364 - 1375
Sumantra Chattarji, Anupratap Tomar, Aparna Suvrathan, Supriya Ghosh and Mohammed Mostafizur Rahman
doi:10.1038/nn.4115
Abstract - | Full Text - Neighborhood matters: divergent patterns of stress-induced plasticity across the brain | PDF (3,201 KB) - Neighborhood matters: divergent patterns of stress-induced plasticity across the brain
Focus on stress
Stress weakens prefrontal networks: molecular insults to higher cognition- pp1376 - 1385
Amy F T Arnsten
doi:10.1038/nn.4087
Abstract - | Full Text - Stress weakens prefrontal networks: molecular insults to higher cognition | PDF (1,532 KB) - Stress weakens prefrontal networks: molecular insults to higher cognition
Focus on stress
Neuroimmune mechanisms of depression- pp1386 - 1393
Georgia E Hodes, Veronika Kana, Caroline Menard, Miriam Merad and Scott J Russo
doi:10.1038/nn.4113
Abstract - | Full Text - Neuroimmune mechanisms of depression | PDF (1,713 KB) - Neuroimmune mechanisms of depression
Focus on stress
Resolving the neural circuits of anxiety- pp1394 - 1404
Gwendolyn G Calhoon and Kay M Tye
doi:10.1038/nn.4101
Abstract - | Full Text - Resolving the neural circuits of anxiety | PDF (1,640 KB) - Resolving the neural circuits of anxiety
Focus on stress
Stress effects on the neural substrates of motivated behavior- pp1405 - 1412
Nick G Hollon, Lauren M Burgeno and Paul E M Phillips
doi:10.1038/nn.4114
Abstract - | Full Text - Stress effects on the neural substrates of motivated behavior | PDF (3,952 KB) - Stress effects on the neural substrates of motivated behavior
Focus on stress
Sex differences and stress across the lifespan- pp1413 - 1420
Tracy L Bale and C Neill Epperson
doi:10.1038/nn.4112
Abstract - | Full Text - Sex differences and stress across the lifespan | PDF (3,952 KB) - Sex differences and stress across the lifespan
Focus on stress
Environmental influence in the brain, human welfare and mental health- pp1421 - 1431
Heike Tost, Frances A Champagne and Andreas Meyer-Lindenberg
doi:10.1038/nn.4108
Abstract - | Full Text - Environmental influence in the brain, human welfare and mental health | PDF (3,952 KB) - Environmental influence in the brain, human welfare and mental health
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