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Editorials

Nature Reports Stem Cells p481

doi:10.1038/ncb0507-481a


Opening the RNAi black box p481

doi:10.1038/ncb0507-481b


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News and Views

Barriers to Ras transformation pp483 - 485

Gerardo Ferbeyre

doi:10.1038/ncb0507-483


Anchoring RCC1 by the tail pp485 - 487

Paul R. Clarke

doi:10.1038/ncb0507-485


Mitochondrial apoptosis without VDAC pp487 - 489

Lorenzo Galluzzi & Guido Kroemer

doi:10.1038/ncb0507-487


p53: a two-faced cancer gene pp489 - 491

Michael B. Kastan & Elijahu Berkovich

doi:10.1038/ncb0507-489


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Articles

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis pp493 - 505

Christopher J. Sarkisian, Blaine A. Keister, Douglas B. Stairs, Robert B. Boxer, Susan E. Moody & Lewis A. Chodosh

doi:10.1038/ncb1567

See also: News and Views by Ferbeyre


Cdk1 coordinates cell-surface growth with the cell cycle pp506 - 515

Derek McCusker, Carilee Denison, Scott Anderson, Thea A. Egelhofer, John R. Yates, 3rd, Steven P. Gygi & Douglas R. Kellogg

doi:10.1038/ncb1568


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Letters

The outer plate in vertebrate kinetochores is a flexible network with multiple microtubule interactions pp516 - 522

Yimin Dong, Kristin J. Vanden Beldt, Xing Meng, Alexey Khodjakov & Bruce F. McEwen

doi:10.1038/ncb1576


Priming, initiation and synchronization of the segmentation clock by deltaD and deltaC pp523 - 530

Andrew Mara, Joshua Schroeder, Cécile Chalouni & Scott A. Holley

doi:10.1038/ncb1578


The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF pp531 - 540

Tarik Regad, Martin Roth, Nicholas Bredenkamp, Nicola Illing & Nancy Papalopulu

doi:10.1038/ncb1573


C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1 pp541 - 549

Xiaochen Wang, Jin Wang, Keiko Gengyo-Ando, Lichuan Gu, Chun-Ling Sun, Chonglin Yang, Yong Shi, Tetsuo Kobayashi, Yigong Shi, Shohei Mitani, Xiao-Song Xie & Ding Xue

doi:10.1038/ncb1574


Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death pp550 - 555

Christopher P. Baines, Robert A. Kaiser, Tatiana Sheiko, William J. Craigen & Jeffery D. Molkentin

doi:10.1038/ncb1575

See also: News and Views by Galluzzi & Kroemer


A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling pp556 - 564

Viji M. Draviam, Frank Stegmeier, Grzegorz Nalepa, Mathew E. Sowa, Jing Chen, Anthony Liang, Gregory J. Hannon, Peter K. Sorger, J. Wade Harper & Stephen J. Elledge

doi:10.1038/ncb1569


Flies without a spindle checkpoint pp565 - 572

Eulalie Buffin, Doruk Emre & Roger E. Karess

doi:10.1038/ncb1570



Loss of Drosophila Myb interrupts the progression of chromosome condensation pp581 - 587

J. Robert Manak, Hong Wen, Tran Van, Laura Andrejka & Joseph S. Lipsick

doi:10.1038/ncb1580


pVHL and GSK3beta are components of a primary cilium-maintenance signalling network pp588 - 595

Claudio R. Thoma, Ian J. Frew, Christian R. Hoerner, Matteo Montani, Holger Moch & Wilhelm Krek

doi:10.1038/ncb1579


N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis pp596 - 603

Ting Chen, Tara L. Muratore, Christine E. Schaner-Tooley, Jeffrey Shabanowitz, Donald F. Hunt & Ian G. Macara

doi:10.1038/ncb1572

See also: News and Views by Clarke


DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs pp604 - 611

Toru Fukuda, Kaoru Yamagata, Sally Fujiyama, Takahiro Matsumoto, Iori Koshida, Kimihiro Yoshimura, Masatomo Mihara, Masanori Naitou, Hideki Endoh, Takashi Nakamura, Chihiro Akimoto, Yoko Yamamoto, Takenobu Katagiri, Charles Foulds, Shinichiro Takezawa, Hirochika Kitagawa, Ken-ichi Takeyama, Bert W. O'Malley & Shigeaki Kato

doi:10.1038/ncb1577


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Addenda

Addenda p612

doi:10.1038/ncb1586


Addenda p612

doi:10.1038/ncb1587


Addenda p612

doi:10.1038/ncb1588


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