Voltage-dependent anion channels (VDACs) are thought to participate in mitochondrial-membrane permeabilization, an event that frequently delimits the frontier between cell life and death. Recent work casts doubts on their contribution to mitochondrial cell death.
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Galluzzi, L., Kroemer, G. Mitochondrial apoptosis without VDAC. Nat Cell Biol 9, 487–489 (2007). https://doi.org/10.1038/ncb0507-487
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DOI: https://doi.org/10.1038/ncb0507-487
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