ChR2: Anniversary Issue

ChR2 coming of age-  p1191

doi:10.1038/nn.4103

10 years ago, channelrhodopsin-2 was expressed in neurons and shown to control their activity. In this issue, we consider how the field has developed since these early optogenetic experiments.

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ChR2: Anniversary Issue

Optogenetics: 10 years after ChR2 in neurons—views from the community- pp1202 - 1212

Antoine Adamantidis, Silvia Arber, Jaideep S Bains, Ernst Bamberg, Antonello Bonci, György Buzsáki, Jessica A Cardin, Rui M Costa, Yang Dan, Yukiko Goda, Ann M Graybiel, Michael Häusser, Peter Hegemann, John R Huguenard, Thomas R Insel, Patricia H Janak, Daniel Johnston, Sheena A Josselyn, Christof Koch, Anatol C Kreitzer, Christian Lüscher, Robert C Malenka, Gero Miesenböck, Georg Nagel, Botond Roska, Mark J Schnitzer, Krishna V Shenoy, Ivan Soltesz, Scott M Sternson, Richard W Tsien, Roger Y Tsien, Gina G Turrigiano, Kay M Tye and Rachel I Wilson

doi:10.1038/nn.4106

On the anniversary of the Boyden et al. (2005) paper that introduced the use of channelrhodopsin in neurons, Nature Neuroscience asks selected members of the community to comment on the utility, impact and future of this important technique.

Full Text - Optogenetics: 10 years after ChR2 in neurons—views from the community | PDF (2,208 KB) - Optogenetics: 10 years after ChR2 in neurons—views from the community