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Radiation therapy with phenotypic medicine: towards N-of-1 personalization
- Li Ming Chong
- , Peter Wang
- & Dean Ho
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ABCC4 suppresses glioblastoma progression and recurrence by restraining cGMP-PKG signalling
- Jung-Ying Chiang
- , Sung-Tai Wei
- & Chia-Hung Hsieh
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Article
| Open AccessEpithelial ovarian cancer survival by race and ethnicity in an equal-access healthcare population
- Zhaohui L. Arter
- , Daniel Desmond
- & Melissa A. Merritt
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Downregulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression
- Nan Xu
- , Jianyong Zhuo
- & Qiang Wei
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| Open AccessBreast cancers with high proliferation and low ER-related signalling have poor prognosis and unique molecular features with implications for therapy
- Luca Licata
- , Marco Barreca
- & Giampaolo Bianchini
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Radiomics-based decision support tool assists radiologists in small lung nodule classification and improves lung cancer early diagnosis
- Benjamin Hunter
- , Christos Argyros
- & Anand Devaraj
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Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts
- Shanshan Shi
- , Kai Wang
- & Mingyang Song
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| Open AccessTargeting hyaluronan-mediated motility receptor (HMMR) enhances response to androgen receptor signalling inhibitors in prostate cancer
- Josephine A. Hinneh
- , Joanna L. Gillis
- & Lisa M. Butler
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Article
| Open AccessEx vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers
- Ioannis Ntafoulis
- , Anne Kleijn
- & Martine L. M. Lamfers
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| Open AccessClassification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program
- Junseong Park
- , Jin-Kyoung Shim
- & Seok-Gu Kang
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Combination of pembrolizumab and pelareorep promotes anti-tumour immunity in advanced pancreatic adenocarcinoma (PDAC)
- Devalingam Mahalingam
- , Siqi Chen
- & Bin Zhang
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| Open AccessCost-effectiveness analysis of molecular testing in minimally invasive samples to detect endometrial cancer in women with postmenopausal bleeding
- Paula Peremiquel-Trillas
- , David Gómez
- & Mireia Díaz
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Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma
- Karrie Mei-Yee Kiang
- , Wanjun Tang
- & Gilberto Ka-Kit Leung
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| Open AccessThe HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination
- Lena Mühlenbruch
- , Tsima Abou-Kors
- & Simon Laban
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PI-RADSAI: introducing a new human-in-the-loop AI model for prostate cancer diagnosis based on MRI
- Ruiqi Yu
- , Ke-wen Jiang
- & Yu-Dong Zhang
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Article |
Serum thrombospondin-1 serves as a novel biomarker and agonist of gemcitabine-based chemotherapy in intrahepatic cholangiocarcinoma
- Dong-yang Ding
- , Xiao-jie Gan
- & Sheng-xian Yuan
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| Open AccessTh2 cells inhibit growth of colon and pancreas cancers by promoting anti-tumorigenic responses from macrophages and eosinophils
- Damian Jacenik
- , Ioannis Karagiannidis
- & Ellen J. Beswick
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| Open AccessIntratumoral heterogeneity affects tumor regression and Ki67 proliferation index in perioperatively treated gastric carcinoma
- Magnus Kock am Brink
- , Laura Sophie Dunst
- & Christoph Röcken
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| Open AccessBreast density is strongly associated with multiparametric magnetic resonance imaging biomarkers and pro-tumorigenic proteins in situ
- Peter Lundberg
- , Mikael F. Forsgren
- & Charlotta Dabrosin
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Perspective |
Extruded small extracellular vesicles: splinters of circulating tumour cells may promote cancer metastasis?
- Yuan Wan
- , Yi-Qiu Xia
- & Si-Yang Zheng
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| Open AccessComprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk
- Mathilde M. Almekinders
- , Tycho Bismeijer
- & Alastair M. Thompson
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Discovery and validation of a transcriptional signature identifying homologous recombination-deficient breast, endometrial and ovarian cancers
- Guillaume Beinse
- , Pierre-Alexandre Just
- & Jérôme Alexandre
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| Open AccessAndrogen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer
- Anna R. Michmerhuizen
- , Lynn M. Lerner
- & Corey W. Speers
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| Open AccessMRI radiomics independent of clinical baseline characteristics and neoadjuvant treatment modalities predicts response to neoadjuvant therapy in rectal cancer
- Maxiaowei Song
- , Shuai Li
- & Weihu Wang
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Tumour growth rate improves tumour assessment and first-line systemic treatment decision-making for immunotherapy in patients with liver metastatic uveal melanoma
- Toulsie Ramtohul
- , Axel Cohen
- & Vincent Servois
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| Open AccessEvaluation of tumour surveillance protocols and outcomes in von Hippel-Lindau disease in a national health service
- Eamonn R. Maher
- , Julian Adlard
- & Richard N. Sandford
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| Open AccessRandomised phase II trial of weekly ixabepilone ± biweekly bevacizumab for platinum-resistant or refractory ovarian/fallopian tube/primary peritoneal cancer
- Dana M. Roque
- , Eric R. Siegel
- & Alessandro D. Santin
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Article
| Open AccessLiquid BIOpsy for MiNimal RESidual DiSease Detection in Head and Neck Squamous Cell Carcinoma (LIONESS)—a personalised circulating tumour DNA analysis in head and neck squamous cell carcinoma
- Susanne Flach
- , Karen Howarth
- & Philipp Baumeister
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Article
| Open AccessAdjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients
- Leonora W. de Boo
- , Katarzyna Jóźwiak
- & Sabine C. Linn
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Increased expression of Profilin potentiates chemotherapeutic agent-mediated tumour regression
- Shashank Saurav
- & Sunil Kumar Manna
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Intratumoural haematopoietic stem and progenitor cell differentiation into M2 macrophages facilitates the regrowth of solid tumours after radiation therapy
- Tyler M. Parsons
- , Katie L. Buelow
- & Gerard J. Madlambayan
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| Open AccessCharacterising 18F-fluciclovine uptake in breast cancer through the use of dynamic PET/CT imaging
- N. P. Scott
- , E. J. Teoh
- & D. R. McGowan
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| Open AccessAn evaluation of a national mass media campaign to raise public awareness of possible lung cancer symptoms in England in 2016 and 2017
- Susan Ball
- , Chris Hyde
- & Lucy Elliss-Brookes
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Review Article |
ESR1 mutations and therapeutic resistance in metastatic breast cancer: progress and remaining challenges
- Sarah K. Herzog
- & Suzanne A. W. Fuqua
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Article
| Open AccessRisk of COVID-19 death in cancer patients: an analysis from Guy’s Cancer Centre and King’s College Hospital in London
- Beth Russell
- , Charlotte L. Moss
- & Mieke Van Hemelrijck
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G-protein subunit gamma-4 expression has potential for detection, prediction and therapeutic targeting in liver metastasis of gastric cancer
- Haruyoshi Tanaka
- , Mitsuro Kanda
- & Yasuhiro Kodera
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Correspondence |
Comment on: “Hypoxia differently modulates the release of mitochondrial and nuclear DNA”
- Boris K. L. Wong
- , Fan Zhang
- & Daniel R. A. Cox
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The added value of H2 antagonists in premedication regimens during paclitaxel treatment
- Juul M. Cox
- , Leni van Doorn
- & Roelof W. F. van Leeuwen
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Kinome-wide analysis of the effect of statins in colorectal cancer
- Sarah Ouahoud
- , Rutger J. Jacobs
- & James C. H. Hardwick
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Correspondence
| Open AccessReply to “Comment on: Increases in arm volume predict lymphoedema and quality of life deficits after axillary surgery: a prospective cohort study”
- Nigel Bundred
- , Chris Todd
- & Vaughan Keeley
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Review Article
| Open AccessOvercoming the challenges associated with CD3+ T-cell redirection in cancer
- Ajit Singh
- , Sundee Dees
- & Iqbal S. Grewal
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Article
| Open AccessDevelopment of a non-invasive exhaled breath test for the diagnosis of head and neck cancer
- Nuwan Dharmawardana
- , Thomas Goddard
- & Roger Yazbeck
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Editorial
| Open AccessBowel inflammation in cancer patients: the microbiome, antibiotics and interleukin-9
- Niels Halama
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Comment
| Open AccessVitamin D supplementation: a potential therapeutic agent for metastatic colorectal cancer
- Chen Yuan
- & Kimmie Ng
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Review Article
| Open AccessNew tools to prevent cancer growth and spread: a ‘Clever’ approach
- Maija Hollmén
- , Carlos R. Figueiredo
- & Sirpa Jalkanen
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Article
| Open AccessImpact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds
- Giovanna Li Petri
- , Btissame El Hassouni
- & Elisa Giovannetti
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Article
| Open AccessCDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms
- Margaretha A. Skowron
- , Marieke Vermeulen
- & Daniel Nettersheim
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Comment
| Open AccessPotential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors
- Amelia McCartney
- & Luca Malorni