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Article
| Open AccessDiscovery of Nedd4 auto-ubiquitination inhibitors
- Darren Yong
- , Stuart R. Green
- & Masoud Vedadi
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Article
| Open AccessMycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis
- Ilona van Alen
- , Mayra A. Aguirre García
- & Marcellus Ubbink
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Article
| Open AccessEvaluation of antibiofilm properties of dehydroacetic acid (DHA) grafted spiro-oxindolopyrrolidines synthesized via multicomponent 1,3-dipolar cycloaddition reaction
- Adukamparai R. Suresh Babu
- , Akanksha Sharma
- & Ravi Pratap Barnwal
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Article
| Open AccessUltrastructural features mirror metabolic derangement in human endothelial cells exposed to high glucose
- Roberta Scrimieri
- , Laura Locatelli
- & Jeanette A. Maier
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Article
| Open AccessStudy of β1-transferrin and β2-transferrin using microprobe-capture in-emitter elution and high-resolution mass spectrometry
- Ruben Yiqi Luo
- , Christopher Pfaffroth
- & Run-Zhang Shi
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Article
| Open AccessValproate regulates inositol synthesis by reducing expression of myo-inositol-3-phosphate synthase
- Kendall C. Case
- , Rachel J. Beltman
- & Miriam L. Greenberg
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Article
| Open AccessStructural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus
- Carl Johan Hagströmer
- , Jonas Hyld Steffen
- & Susanna Törnroth-Horsefield
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Article
| Open AccessActivation of oxidoreductases by the formation of enzyme assembly
- Tomoto Ura
- , Nanako Sakakibara
- & Tsutomu Mikawa
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Article
| Open AccessDesign of an alternate antibody fragment format that can be produced in the cytoplasm of Escherichia coli
- Aatir A. Tungekar
- & Lloyd W. Ruddock
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Article
| Open AccessThe unusual properties of lactoferrin during its nascent phase
- Sara Notari
- , Giorgia Gambardella
- & Giorgio Ricci
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Article
| Open AccessIntracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis
- Uddhab Karki
- , Paula Perez Sanchez
- & Jianfeng Xu
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Article
| Open AccessEffects of neutron radiation generated in deep space-like environments on food resources
- Machiko Hatsuda
- , Hiroaki Kawasaki
- & Fumiyuki Yamakura
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Article
| Open AccessAntibody binding of amyloid beta peptide epimers/isomers and ramifications for immunotherapies and drug development
- Elizabeth R. Readel
- , Arzoo Patel
- & Daniel W. Armstrong
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Article
| Open AccessExploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases
- Jan Kägi
- , Willough Sloan
- & Thorsten Friedrich
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Article
| Open AccessDetection, visualization and quantification of protein complexes in human Alzheimer’s disease brains using proximity ligation assay
- Wilber Romero-Fernandez
- , Cristian Carvajal-Tapia
- & Matthew S. Schrag
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Article
| Open AccessDeveloping a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy
- Noam Tzuri
- , Ksenia M. Yegodayev
- & Niv Papo
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Article
| Open AccessIdentification and validation of fusidic acid and flufenamic acid as inhibitors of SARS-CoV-2 replication using DrugSolver CavitomiX
- M. Hetmann
- , C. Langner
- & C. C. Gruber
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Article
| Open AccessX-ray driven and intrinsic dynamics in protein gels
- Sonja Timmermann
- , Nimmi Das Anthuparambil
- & Christian Gutt
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Article
| Open AccessFluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators
- Osha Roopnarine
- , Samantha L. Yuen
- & David D. Thomas
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Article
| Open AccessN-glycans from serum IgG and total serum glycoproteins specific for endometriosis
- Zsuzsanna Kovács
- , Fiona Reidy
- & Radka Saldova
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Article
| Open AccessProteomic analysis of the effect of hemin in breast cancer
- G. P. Coló
- , K. Schweitzer
- & M. M. Facchinetti
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Article
| Open AccessIntact mass analysis reveals the novel O-linked glycosylation on the stalk region of PD-1 protein
- Phanthakarn Tit-oon
- , Arisa Wonglangka
- & Amnart Khongmanee
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Article
| Open AccessPolyproline type II helical antifreeze proteins are widespread in Collembola and likely originated over 400 million years ago in the Ordovician Period
- Connor L. Scholl
- , Martin Holmstrup
- & Peter L. Davies
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Article
| Open AccessEffects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules’ physical properties and neurite morphology
- Kohei Nishida
- , Kosuke Matsumura
- & Kiyotaka Tokuraku
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Article
| Open AccessMolecular structure of soluble vimentin tetramers
- Pieter-Jan Vermeire
- , Anastasia V. Lilina
- & Sergei V. Strelkov
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Article
| Open AccessRapid and efficient ambient temperature X-ray crystal structure determination at Turkish Light Source
- Mehmet Gul
- , Esra Ayan
- & Hasan DeMi̇rci̇
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Article
| Open AccessDifferent electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1
- Valeria Pennacchietti
- & Angelo Toto
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Article
| Open AccessFUS fibrillation occurs through a nucleation-based process below the critical concentration required for liquid–liquid phase separation
- Emilie Bertrand
- , Clément Demongin
- & Loic Hamon
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Article
| Open AccessDiscovery of two new isoforms of the human DUT gene
- Gergely Attila Rácz
- , Nikolett Nagy
- & Beáta G. Vértessy
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Article
| Open AccessThe difference in the cellular uptake of tocopherol and tocotrienol is influenced by their affinities to albumin
- Takashi Nakatomi
- , Mayuko Itaya-Takahashi
- & Kiyotaka Nakagawa
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Article
| Open AccessThe cytoplasmic N-terminal tail of Zika virus NS4A protein forms oligomers in the absence of detergent or lipids
- Wahyu Surya
- , Yiting Liu
- & Jaume Torres
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Article
| Open AccessIn vivo imaging of MmpL transporters reveals distinct subcellular locations for export of mycolic acids and non-essential trehalose polyphleates in the mycobacterial outer membrane
- Laurie Thouvenel
- , Jérôme Rech
- & Christian Chalut
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Article
| Open AccessA widely applicable and cost-effective method for specific RNA–protein complex isolation
- Sam Balzarini
- , Roosje Van Ende
- & Koen Geuten
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Article
| Open AccessMechanism of rotenone binding to respiratory complex I depends on ligand flexibility
- Caroline S. Pereira
- , Murilo H. Teixeira
- & Guilherme M. Arantes
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Article
| Open AccessMass spectrometry-based proteomic strategy for ecchymotic skin examination in forensic pathology
- Lorenzo Toma
- , Giulia Vignali
- & Stefano Bruno
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Article
| Open AccessRational design of phase separating peptides based on phase separating protein sequence of p53
- Kiyoto Kamagata
- , Atsumi Hando
- & Keisuke Ikeda
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Article
| Open AccessRNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific
- Debashish Ray
- , Kaitlin U. Laverty
- & Timothy R. Hughes
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Article
| Open AccessDiscovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays
- Priyanka Parijat
- , Saraswathi Ponnam
- & Thomas Kampourakis
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Article
| Open AccessCoenzyme A binding sites induce proximal acylation across protein families
- Chris Carrico
- , Andrew Cruz
- & Eric Verdin
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Article
| Open AccessMyosin light chain of shark fast skeletal muscle exhibits intrinsic urea-resistibility
- Satoshi Kanoh
- , Takayuki Noma
- & Daisuke Funabara
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Article
| Open AccessNatural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII in a dry state
- Maxwell H. Packebush
- , Silvia Sanchez-Martinez
- & Thomas C. Boothby
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Article
| Open AccessCollagen constitutes about 12% in females and 17% in males of the total protein in mice
- Katharina Tarnutzer
- , Devanarayanan Siva Sankar
- & Collin Y. Ewald
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Article
| Open AccessGRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production
- Aline Sandouk
- , Zhen Xu
- & Jon C. D. Houtman
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Article
| Open AccessResidue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides
- Elina Berntsson
- , Faraz Vosough
- & Sebastian K. T. S. Wärmländer
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Article
| Open AccessComputational analysis of the sequence-structure relation in SARS-CoV-2 spike protein using protein contact networks
- Pietro Hiram Guzzi
- , Luisa di Paola
- & Pierangelo Veltri
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Article
| Open AccessMultiple plasma membrane reporters discern LHFPL5 region that blocks trafficking to the plasma membrane
- David C. Soler
- , Angela Ballesteros
- & Ruben Stepanyan
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Article
| Open AccessMetal-induced oxidative stress and human plasma protein oxidation after SARS-CoV-2 infection
- Baikuntha Aryal
- , Joseph Tillotson
- & V. Ashutosh Rao
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Article
| Open AccessAlternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms
- Myriah L. Acuña
- , Andrea García-Morin
- & Germán Rosas-Acosta
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Article
| Open AccessA mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro
- Jennifer R. Shelley
- , Brian J. McHugh
- & Donald J. Davidson
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