Nuclear receptors articles within Scientific Reports

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• Article
  26 September 2023 | Open Access

  Decoding the dual recognition mechanism of the glucocorticoid receptor for DNA and RNA: sequence versus shape

  • Johanna Hörberg
  •  & Anna Reymer

• Article
  17 August 2021 | Open Access

  Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal

  • Keiji Tanimoto
  • , Kiichi Hirota
  •  & Takemasa Sakaguchi

• Article
  29 June 2021 | Open Access

  The effect of protein mutations on drug binding suggests ensuing personalised drug selection

  • Shunzhou Wan
  • , Deepak Kumar
  •  & Peter V. Coveney

• Article
  12 April 2021 | Open Access

  Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases

  • Patrick Meylan
  • , Christine Pich
  •  & Liliane Michalik

• Article
  06 October 2020 | Open Access

  LncRNA-AK149641 regulates the secretion of tumor necrosis factor-α in P815 mast cells by targeting the nuclear factor-kappa B signaling pathway

  • Yao Zhou
  • , Li-na Gu
  •  & Feng Liu

• Article
  01 July 2020 | Open Access

  Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation

  • Mihee Oh
  • , Sun Young Kim
  •  & Baek-Soo Han

• Article
  13 January 2020 | Open Access

  The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids

  • Sarah Ducastel
  • , Véronique Touche
  •  & Sophie Lestavel

• Article
  09 December 2019 | Open Access

  Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen

  • Dinuka De Silva
  • , Zhentao Zhang
  •  & Young E. Whang

• Article
  03 December 2019 | Open Access

  Indirubin-pregnane X receptor-JNK axis accelerates skin wound healing

  • Yuka Tanaka
  • , Hiroshi Uchi
  •  & Masutaka Furue

• Article
  20 November 2019 | Open Access

  Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis

  • Gagan D. Flora
  • , Khaled A. Sahli
  •  & Jonathan M. Gibbins

• Article
  11 October 2019 | Open Access

  Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling

  • Rami M. El Zein
  • , Audrey H. Soria
  •  & Sheerazed Boulkroun

• Article
  26 July 2019 | Open Access

  The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis

  • Laura Lozza
  • , Pedro Moura-Alves
  •  & Stefan H. E. Kaufmann

• Article
  30 May 2019 | Open Access

  Vitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts

  • Gemma Ferrer-Mayorga
  • , Núria Niell
  •  & María Jesús Larriba

• Article
  24 January 2019 | Open Access

  Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells

  • Ludovica Marinelli
  • , Camille Martin-Gallausiaux
  •  & Nicolas Lapaque

• Article
  24 September 2018 | Open Access

  Novel role for receptor dimerization in post-translational processing and turnover of the GRα

  • Legh Wilkinson
  • , Nicolette Verhoog
  •  & Ann Louw

• Article
  13 June 2018 | Open Access

  Without 1α-hydroxylation, the gene expression profile of 25(OH)D₃ treatment overlaps deeply with that of 1,25(OH)₂D₃ in prostate cancer cells

  • Takao Susa
  • , Masayoshi Iizuka
  •  & Tomoki Okazaki

• Article
  30 November 2017 | Open Access

  Profiling of the transcriptional response to all-trans retinoic acid in breast cancer cells reveals RARE-independent mechanisms of gene expression

  • Krysta Mila Coyle
  • , Selena Maxwell
  •  & Paola Marcato

• Article
  07 September 2017 | Open Access

  β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction

  • Malik Quasir Mahmood
  • , Eugene Haydn Walters
  •  & Sukhwinder Singh Sohal

• Article
  23 August 2017 | Open Access

  The activation of PPARγ by 2,4,6-Octatrienoic acid protects human keratinocytes from UVR-induced damages

  • Enrica Flori
  • , Arianna Mastrofrancesco
  •  & Mauro Picardo

• Article
  06 July 2017 | Open Access

  HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis

  • Ingrid Lema
  • , Larbi Amazit
  •  & Say Viengchareun

• Article
  28 June 2017 | Open Access

  A Quantitative Study of Internal and External Interactions of Homodimeric Glucocorticoid Receptor Using Fluorescence Cross-Correlation Spectroscopy in a Live Cell

  • Manisha Tiwari
  • , Sho Oasa
  •  & Masataka Kinjo

• Article
  16 June 2017 | Open Access

  Novel complex of HAT protein TIP60 and nuclear receptor PXR promotes cell migration and adhesion

  • Karishma Bakshi
  • , B. Ranjitha
  •  & Ashish Gupta

• Article
  01 June 2017 | Open Access

  VEGF-A Stimulates STAT3 Activity via Nitrosylation of Myocardin to Regulate the Expression of Vascular Smooth Muscle Cell Differentiation Markers

  • Xing Hua Liao
  • , Yuan Xiang
  •  & Tong Cun Zhang

• Article
  23 May 2017 | Open Access

  NAD⁺ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD⁺ repletion

  • Silvia Diani-Moore
  • , Jenny Shoots
  •  & Arleen B. Rifkind

• Article
  24 April 2017 | Open Access

  Glucose-dependent regulation of pregnane X receptor is modulated by AMP-activated protein kinase

  • Peter O. Oladimeji
  • , Wenwei Lin
  •  & Taosheng Chen

• Article
  23 March 2017 | Open Access

  Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma

  • Wenjun Zeng
  • , Chunyun Zhang
  •  & Jin-Zhang Zeng

• Article
  21 March 2017 | Open Access

  Agonist-mediated assembly of the crustacean methyl farnesoate receptor

  • Elizabeth K. Medlock Kakaley
  • , Helen Y. Wang
  •  & Gerald A. LeBlanc

• Article
  07 March 2017 | Open Access

  Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells

  • Malgorzata Nepelska
  • , Tomas de Wouters
  •  & Hervé M. Blottière

• Article
  24 February 2017 | Open Access

  High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with aP2-Cre-mediated Deletion of Estrogen Receptor Alpha

  • Zsofia Ban
  • , Paul Maurischat
  •  & Ulrich Kintscher

• Article
  06 January 2017 | Open Access

  C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ

  • Jung-Hoon Kim
  • , Soyeon Shin
  •  & Jaewhan Song

• Article
  15 November 2016 | Open Access

  Fasting and Feeding Signals Control the Oscillatory Expression of Angptl8 to Modulate Lipid Metabolism

  • Fabin Dang
  • , Rong Wu
  •  & Yi Liu

• Article
  06 October 2016 | Open Access

  Single cell dynamic phenotyping

  • Katherin Patsch
  • , Chi-Li Chiu
  •  & Daniel Ruderman

• Article
  13 July 2016 | Open Access

  Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages

  • Si-Yoon Kim
  • , Eun-Jin Lim
  •  & Jihee Lee Kang

• Article
  23 June 2016 | Open Access

  Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation

  • David S. Moura
  • , Isabel F. Fernández
  •  & Pedro A. Lazo

• Article
  06 May 2016 | Open Access

  The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms

  • Benoit Pourcet
  • , Matthew C. Gage
  •  & Inés Pineda-Torra

• Article
  28 April 2016 | Open Access

  The orphan nuclear receptor NR4A2 is part of a p53–microRNA-34 network

  • Jordan A. Beard
  • , Alexa Tenga
  •  & Taosheng Chen

• Article
  24 March 2016 | Open Access

  Dynamin II is required for 17β-estradiol signaling and autophagy-based ERα degradation

  • Pierangela Totta
  • , Claudia Busonero
  •  & Filippo Acconcia

• Article
  03 March 2016 | Open Access

  Intracellular kinetics of the androgen receptor shown by multimodal Image Correlation Spectroscopy (mICS)

  • Chi-Li Chiu
  • , Katherin Patsch
  •  & Daniel Ruderman

• Article
  05 February 2016 | Open Access

  Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells

  • Jan Däbritz
  • , Louise M. Judd
  •  & Andrew S. Giraud

• Article
  24 November 2015 | Open Access

  A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology

  • Linn Iren Hodneland Nilsson
  • , Ina Katrine Nitschke Pettersen
  •  & Karl Johan Tronstad

• Article
  09 November 2015 | Open Access

  Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2)

  • Andre Madsen
  • , Olivera Bozickovic
  •  & Jørn V. Sagen

• Article
  22 September 2015 | Open Access

  Statin-activated nuclear receptor PXR promotes SGK2 dephosphorylation by scaffolding PP2C to induce hepatic gluconeogenesis

  • Saki Gotoh
  •  & Masahiko Negishi

• Article
  08 June 2015 | Open Access

  The actions of neurotensin in rat bladder detrusor contractility

  • Xingyou Dong
  • , Xinyu Bai
  •  & Longkun Li

• Article
  14 May 2015 | Open Access

  Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer

  • Kimiko Inoue
  • , Mami Oikawa
  •  & Atsuo Ogura

• Article
  13 May 2015 | Open Access

  Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis

  • Sameer S. Udhane
  • , Amit V. Pandey
  •  & Christa E. Flück

• Article
  23 August 2013 | Open Access

  Induction of Pax3 gene expression impedes cardiac differentiation

  • Qiao Li
  • , Melanie Le May
  •  & Jihong Chen

• Article
  19 February 2013 | Open Access

  Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs

  • Surbhi Dhar
  • , Vidyasiri Vemulapalli
  •  & Mark T. Bedford

• Article
  06 December 2012 | Open Access

  Prevalent Glucocorticoid and Androgen Activity in US Water Sources

  • Diana A. Stavreva
  • , Anuja A. George
  •  & Gordon L. Hager