Featured
-
-
Article
| Open AccessExperimental and computational evidence that Calpain-10 binds to the carboxy terminus of NaV1.2 and NaV1.6
- Luis Manuel Arratia
- , Juan David Bermudes-Contreras
- & Absalom Zamorano-Carrillo
-
Article
| Open AccessDevelopment of tight junction-strengthening compounds using a high-throughput screening system to evaluate cell surface-localized claudin-1 in keratinocytes
- Hiroki Sakamoto
- , Momoyo Nishikawa
- & Seigo Yamada
-
Article
| Open AccessThe Ykt6–Snap29–Syx13 SNARE complex promotes crinophagy via secretory granule fusion with Lamp1 carrier vesicles
- Győző Szenci
- , Gábor Glatz
- & Gábor Juhász
-
Article
| Open AccessKinetic study of membrane protein interactions: from three to two dimensions
- Vladimir Adrien
- , Myriam Reffay
- & Wladimir Urbach
-
Article
| Open AccessExperimental and computational methods to highlight behavioural variations in TonB-dependent transporter expression in Pseudomonas aeruginosa versus siderophore concentration
- Thibaut Hubert
- , Morgan Madec
- & Isabelle J. Schalk
-
Article
| Open AccessInhibition of the norA gene expression and the NorA efflux pump by the tannic acid
- Saulo Relison Tintino
- , Polrat Wilairatana
- & Tereza Cristina Leal Balbino
-
Article
| Open AccessStructural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus
- Carl Johan Hagströmer
- , Jonas Hyld Steffen
- & Susanna Törnroth-Horsefield
-
Article
| Open AccessExploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases
- Jan Kägi
- , Willough Sloan
- & Thorsten Friedrich
-
Article
| Open AccessFluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators
- Osha Roopnarine
- , Samantha L. Yuen
- & David D. Thomas
-
Article
| Open AccessIntact mass analysis reveals the novel O-linked glycosylation on the stalk region of PD-1 protein
- Phanthakarn Tit-oon
- , Arisa Wonglangka
- & Amnart Khongmanee
-
Article
| Open AccessIn vivo imaging of MmpL transporters reveals distinct subcellular locations for export of mycolic acids and non-essential trehalose polyphleates in the mycobacterial outer membrane
- Laurie Thouvenel
- , Jérôme Rech
- & Christian Chalut
-
Article
| Open AccessStructure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM
- Jean-Marc Jeckelmann
- , Thomas Lemmin
- & Dimitrios Fotiadis
-
Article
| Open AccessHeterologously secreted MbxA from Moraxella bovis induces a membrane blebbing response of the human host cell
- Isabelle N. Erenburg
- , Sebastian Hänsch
- & Lutz Schmitt
-
Article
| Open AccessDetermination of the boundary lipids of sticholysins using tryptophan quenching
- Juan Palacios-Ortega
- , Rafael Amigot-Sánchez
- & J. Peter Slotte
-
Article
| Open AccessMutations conferring SO42− pumping ability on the cyanobacterial anion pump rhodopsin and the resultant unique features of the mutant
- Yuhei Doi
- , Jo Watanabe
- & Takashi Kikukawa
-
Article
| Open AccessBeovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in vitro
- Heidrun L. Deissler
- , Catharina Busch
- & Matus Rehak
-
Article
| Open AccessElectrostatic interactions between single arginine and phospholipids modulate physiological properties of sarcoplasmic reticulum Ca2+-ATPase
- Kazuo Yamasaki
- , Takashi Daiho
- & Hiroshi Suzuki
-
Article
| Open AccessPurification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor
- Shangji Zhang
- , Debra T. Hansen
- & Petra Fromme
-
Article
| Open AccessYeast-based directed-evolution for high-throughput structural stabilization of G protein-coupled receptors (GPCRs)
- M. Meltzer
- , T. Zvagelsky
- & Stanislav Engel
-
Article
| Open AccessSophisticated expression responses of ZNT1 and MT in response to changes in the expression of ZIPs
- Shino Nagamatsu
- , Yukina Nishito
- & Taiho Kambe
-
Article
| Open AccessTransport efficiency of AtGTR1 dependents on the hydrophobicity of transported glucosinolates
- Yi-Chia Chung
- , Hao-Yu Cheng
- & Shih-Ming Lin
-
Article
| Open AccessGLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems
- Cristina V. Iancu
- , Giovanni Bocci
- & Jun-yong Choe
-
Article
| Open AccessBiophysical characterization of the homodimers of HomA and HomB, outer membrane proteins of Helicobacter pylori
- Anubhav Tamrakar
- , Rahul Singh
- & Prashant Kodgire
-
Article
| Open AccessBiophysical and functional characterization of the human TAS1R2 sweet taste receptor overexpressed in a HEK293S inducible cell line
- Christine Belloir
- , Marine Brulé
- & Loïc Briand
-
Article
| Open AccessRigidity of loop 1 contributes to equipotency of globular and ribbon isomers of α-conotoxin AusIA
- Thao N. T. Ho
- , Nikita Abraham
- & Richard J. Lewis
-
Article
| Open AccessA bimolecular fluorescence complementation flow cytometry screen for membrane protein interactions
- Florian Schmitz
- , Jessica Glas
- & Kristina Hedfalk
-
Article
| Open AccessEngineering and functional characterization of a proton-driven β-lactam antibiotic translocation module for bionanotechnological applications
- Mirko Stauffer
- , Zöhre Ucurum
- & Dimitrios Fotiadis
-
Article
| Open AccessACE2 protein expression within isogenic cell lines is heterogeneous and associated with distinct transcriptomes
- Emily J. Sherman
- & Brian T. Emmer
-
Article
| Open AccessKinetic characterisation and inhibitor sensitivity of Candida albicans and Candida auris recombinant AOX expressed in a self-assembled proteoliposome system
- Alice C. Copsey
- , Mario R. O. Barsottini
- & Anthony L. Moore
-
Article
| Open AccessElectrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei
- Sami Havukainen
- , Jonai Pujol-Giménez
- & Christopher P. Landowski
-
Article
| Open AccessIdentification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems
- Sina Schmidl
- , Oleg Ursu
- & Jun-yong Choe
-
Article
| Open AccessAngle change of the A-domain in a single SERCA1a molecule detected by defocused orientation imaging
- Takanobu A. Katoh
- , Takashi Daiho
- & Hiroshi Suzuki
-
Article
| Open AccessBiochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I
- Franziska Nuber
- , Johannes Schimpf
- & Thorsten Friedrich
-
Article
| Open AccessStructural and functional insights into the mechanism of action of plant borate transporters
- Savvas Saouros
- , Thotegowdanapalya C. Mohan
- & Bernadette Byrne
-
Article
| Open AccessExtracellular mutation induces an allosteric effect across the membrane and hampers the activity of MRP1 (ABCC1)
- Yuval Bin Kanner
- , Assaf Ganoth
- & Yossi Tsfadia
-
Article
| Open AccessMolecular model of a sensor of two-component signaling system
- Yury L. Ryzhykau
- , Philipp S. Orekhov
- & Valentin I. Gordeliy
-
Article
| Open AccessATP hydrolysis and nucleotide exit enhance maltose translocation in the MalFGK2E importer
- Bárbara Abreu
- , Carlos Cruz
- & Cláudio M. Soares
-
Article
| Open AccessParacoccus denitrificans: a genetically tractable model system for studying respiratory complex I
- Owen D. Jarman
- , Olivier Biner
- & Judy Hirst
-
Article
| Open AccessInsight into the direct interaction of Na+ with NhaA and mechanistic implications
- Matthias Quick
- , Manish Dwivedi
- & Etana Padan
-
Article
| Open AccessIdentifying the major lactate transporter of Toxoplasma gondii tachyzoites
- Joy M. Zeng
- , Sanduni V. Hapuarachchi
- & Adele M. Lehane
-
Article
| Open AccessCrystal structure of RahU, an aegerolysin protein from the human pathogen Pseudomonas aeruginosa, and its interaction with membrane ceramide phosphorylethanolamine
- Eva Kočar
- , Tea Lenarčič
- & Matej Butala
-
Article
| Open AccessCharacterisation of a tripartite α-pore forming toxin from Serratia marcescens
- Alicia M. Churchill-Angus
- , Thomas H. B. Schofield
- & Patrick J. Baker
-
Article
| Open AccessKnocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth
- Sahar Shekoohi
- , Santhanasabapathy Rajasekaran
- & Stephan N. Witt
-
Article
| Open AccessA plant plasma-membrane H+-ATPase promotes yeast TORC1 activation via its carboxy-terminal tail
- Elie Saliba
- , Cecilia Primo
- & Bruno André
-
Article
| Open AccessThree-dimensional structure of human cyclooxygenase (hCOX)-1
- Morena Miciaccia
- , Benny Danilo Belviso
- & Antonio Scilimati
-
Article
| Open AccessAltered functional properties of the codling moth Orco mutagenized in the intracellular loop-3
- Yuriy V. Bobkov
- , William B. Walker III
- & Alberto Maria Cattaneo
-
Article
| Open AccessCholesterol as a modulator of cannabinoid receptor CB2 signaling
- Alexei Yeliseev
- , Malliga R. Iyer
- & Klaus Gawrisch
-
Article
| Open AccessPentapartite fractionation of particles in oral fluids by differential centrifugation
- Chiho Hiraga
- , Satoshi Yamamoto
- & Kiyotaka Shiba
-
Article
| Open AccessSarcolipin alters SERCA1a interdomain communication by impairing binding of both calcium and ATP
- Cédric Montigny
- , Dong Liang Huang
- & Nadège Jamin