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Optimization of IL-1RA structure to achieve a smaller protein with a higher affinity to its receptor
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Structural basis of human PDZD8–Rab7 interaction for the ER-late endosome tethering
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A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne–Kalscheuer syndrome
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TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes
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Enhanced skeletal muscle insulin sensitivity after acute resistance-type exercise is upregulated by rapamycin-sensitive mTOR complex 1 inhibition
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Binding site plasticity in viral PPxY Late domain recognition by the third WW domain of human NEDD4
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Molecular Dynamics Study of the Changes in Conformation of Calmodulin with Calcium Binding and/or Target Recognition
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Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8
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Crystal structure of a Ca2+-dependent regulator of flagellar motility reveals the open-closed structural transition
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The PII signaling protein from red algae represents an evolutionary link between cyanobacterial and Chloroplastida PII proteins
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Runx2 mediated Induction of Novel Targets ST2 and Runx3 Leads to Cooperative Regulation of Hypertrophic Differentiation in ATDC5 Chondrocytes
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Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR
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Conventional and unconventional secretory proteins expressed with silkworm bombyxin signal peptide display functional fidelity
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Fenugreek supplementation during high-fat feeding improves specific markers of metabolic health
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Modulation of cyclic nucleotide-mediated cellular signaling and gene expression using photoactivated adenylyl cyclase as an optogenetic tool
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Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners
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Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin
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Divergent Anabolic Signalling responses of Murine Soleus and Tibialis Anterior Muscles to Chronic 2G Hypergravity
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DLX3 interacts with GCM1 and inhibits its transactivation-stimulating activity in a homeodomain-dependent manner in human trophoblast-derived cells
- Sha Li
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Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems
- Gaigai Yu
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CaM/BAG5/Hsc70 signaling complex dynamically regulates leaf senescence
- Luhua Li
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The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise
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β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ
- Congcong Wang
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Procaspase-9 induces its cleavage by transnitrosylating XIAP via the Thioredoxin system during cerebral ischemia-reperfusion in rats
- Dengyue Zhang
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Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice
- Elizabeth S Chan
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Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers
- Christopher Weinert
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A decline of LAMP- 2 predicts ursodeoxycholic acid response in primary biliary cirrhosis
- Lu Wang
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Caught in Action: Selecting Peptide Aptamers Against Intrinsically Disordered Proteins in Live Cells
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Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice
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Conformational change of Sos-derived proline-rich peptide upon binding Grb2 N-terminal SH3 domain probed by NMR
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Pigment Epithelium-Derived Factor Secreted from Retinal Pigment Epithelium Facilitates Apoptotic Cell Death of iPSC
- Hoshimi Kanemura
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PAPTi: A Peptide Aptamer Interference Toolkit for Perturbation of Protein-Protein Interaction Networks
- Johannes T. -H. Yeh
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p38 MAPK mediates calcium oxalate crystal-induced tight junction disruption in distal renal tubular epithelial cells
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GRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production