Featured
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Enabling Technologies |
Quantitative morphological comparison of axon-targeting strategies for gene therapies directed to the nigro-striatal projection
- S Padmanabhan
- , T Kareva
- & R E Burke
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Original Article |
Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure model
- C Weber
- , I Neacsu
- & S T Pleger
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Original Article |
A compact dual promoter adeno-associated viral vector for efficient delivery of two genes to dorsal root ganglion neurons
- N D Fagoe
- , R Eggers
- & M R J Mason
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Original Article |
In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV
- P S Montenegro-Miranda
- , V Pichard
- & P J Bosma
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Original Article |
Suicide gene approach using a dual-expression lentiviral vector to enhance the safety of ex vivo gene therapy for bone repair
- F Alaee
- , O Sugiyama
- & J R Lieberman
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Original Article |
A novel gene delivery method transduces porcine pancreatic duct epithelial cells
- M A Griffin
- , M S Restrepo
- & A Uc
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Original Article |
Virally expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice
- Q Yu
- , Y Wang
- & X Lin
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Original Article |
Enhanced antitumor immunotherapeutic effect of B-cell-based vaccine transduced with modified adenoviral vector containing type 35 fiber structures
- E-K Kim
- , H-S Seo
- & C-Y Kang
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Original Article |
Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach
- F M Mowat
- , K R Gornik
- & J T Bartoe
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Original Article
| Open AccessAdeno-associated virus serotypes 9 and rh10 mediate strong neuronal transduction of the dog brain
- G P Swain
- , M Prociuk
- & C H Vite
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Original Article |
Adeno-associated virus type 6 is retrogradely transported in the non-human primate brain
- W San Sebastian
- , L Samaranch
- & K S Bankiewicz
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Original Article |
The MRI contrast agent gadoteridol enhances distribution of rAAV1 in the rat hippocampus
- R Hullinger
- , J Ugalde
- & C Burger
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Original Article
| Open AccessPseudotyping the adenovirus serotype 5 capsid with both the fibre and penton of serotype 35 enhances vascular smooth muscle cell transduction
- A L Parker
- , K M White
- & A H Baker
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Original Article |
PEGylated helper-dependent adenoviral vector expressing human Apo A-I for gene therapy in LDLR-deficient mice
- E Leggiero
- , D Astone
- & L Pastore
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Original Article |
Efficacy of oncolytic adenovirus expressing suicide genes and interleukin-12 in preclinical model of prostate cancer
- S O Freytag
- , K N Barton
- & Y Zhang
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Original Article |
Downregulation of Stat3 in melanoma: reprogramming the immune microenvironment as an anticancer therapeutic strategy
- P U Emeagi
- , S Maenhout
- & K Breckpot
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Original Article
| Open AccessRole of antigen-specific regulatory CD4+CD25+ T cells in tolerance induction after neonatal IP administration of AAV-hF.IX
- Y Shi
- , R Falahati
- & K M L Gaensler
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Mini Review |
Current progress on gene therapy for primary immunodeficiencies
- L Zhang
- , A J Thrasher
- & H B Gaspar
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Short Communication |
The immunogenicity of virus-derived 2A sequences in immunocompetent individuals
- C Arber
- , H Abhyankar
- & B Savoldo
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Original Article |
Characterization of a third generation lentiviral vector pseudotyped with Nipah virus envelope proteins for endothelial cell transduction
- S R Witting
- , P Vallanda
- & A L Gamble
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Original Article |
Efficient transduction of vascular smooth muscle cells with a translational AAV2.5 vector: a new perspective for in-stent restenosis gene therapy
- A-M Lompré
- , L Hadri
- & L Lipskaia
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Short Communication |
No tumour-initiating risk associated with scAAV transduction in newborn rat liver
- V Gauttier
- , V Pichard
- & S Conchon
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Original Article |
Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors
- B-Y Hwang
- & D V Schaffer
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Original Article |
Retinal gene therapy with a large MYO7A cDNA using adeno-associated virus
- V S Lopes
- , S E Boye
- & D S Williams
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Original Article |
Expression of HSV-1 receptors in EBV-associated lymphoproliferative disease determines susceptibility to oncolytic HSV
- P-Y Wang
- , M A Currier
- & T P Cripe
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Original Article |
Comparative effectiveness of antinociceptive gene therapies in animal models of diabetic neuropathic pain
- Y Wang
- , M O Nowicki
- & E A Chiocca
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Review |
Understanding lentiviral vector chromatin targeting: working to reduce insertional mutagenic potential for gene therapy
- C Papayannakos
- & R Daniel
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Original Article |
Venezuelan equine encephalitis virus glycoprotein pseudotyping confers neurotropism to lentiviral vectors
- A Trabalza
- , C Georgiadis
- & N D Mazarakis
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Original Article |
A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism
- M O Alberti
- , J S Deshane
- & J C Roth
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Original Article |
scAAV-mediated gene transfer of interleukin-1-receptor antagonist to synovium and articular cartilage in large mammalian joints
- R S Watson
- , T A Broome
- & S C Ghivizzani
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Original Article |
Hairpin-end conformation of adeno-associated virus genome determines interactions with DNA-repair pathways
- M P Cataldi
- & D M McCarty
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Original Article |
Modulation of feeding by chronic rAAV expression of a relaxin-3 peptide agonist in rat hypothalamus
- D E Ganella
- , G E Callander
- & R A D Bathgate
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Original Article |
Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord
- H Peluffo
- , E Foster
- & R J Yáñez-Muñoz
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Original Article |
Sodium iodide symporter (NIS)-mediated radiovirotherapy of hepatocellular cancer using a conditionally replicating adenovirus
- G K Grünwald
- , K Klutz
- & C Spitzweg
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Original Article |
Oncolytic measles virus strains have significant antitumor activity against glioma stem cells
- C Allen
- , M Opyrchal
- & E Galanis
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Original Article |
Measles virus selectively blind to signaling lymphocyte activation molecule as a novel oncolytic virus for breast cancer treatment
- T Sugiyama
- , M Yoneda
- & C Kai
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Original Article
| Open AccessModulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK
- C L Skelly
- , Q He
- & R Weichselbaum
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Original Article |
A reporter system for replication-competent gammaretroviruses: the inGluc-MLV-DERSE assay
- A L Aloia
- , L Duffy
- & A Rein
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Original Article |
Coxsackievirus B3 used as a gene therapy vector to express functional FGF2
- D-S Kim
- , H Kim
- & J-H Nam
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Original Article
| Open AccessBacterial magnetic particles as a novel and efficient gene vaccine delivery system
- Y-S Tang
- , D Wang
- & S Zhang
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Original Article |
Evaluation of macrophage-specific promoters using lentiviral delivery in mice
- M C Levin
- , U Lidberg
- & I Gjertsson
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Original Article |
GALV expression enhances the therapeutic efficacy of an oncolytic adenovirus by inducing cell fusion and enhancing virus distribution
- S Guedan
- , D Grases
- & R Alemany
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Original Article |
Shutdown of immunological priming and presentation after in vivo administration of adenovirus
- R M Sutherland
- , S L Londrigan
- & A M Lew
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Original Article |
In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression
- A A Rahim
- , A M Wong
- & S N Waddington
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Original Article |
Vector-mediated expression of erythropoietin improves functional outcome after cervical spinal cord contusion injury
- S Wang
- , Z Wu
- & M Mata
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Original Article |
Long-term increase in uterine blood flow is achieved by local overexpression of VEGF-A165 in the uterine arteries of pregnant sheep
- V Mehta
- , K N Abi-Nader
- & A L David
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Original Article |
A cathepsin-cleavage site between the adenovirus capsid protein IX and a tumor-targeting ligand improves targeted transduction
- J de Vrij
- , I J C Dautzenberg
- & R C Hoeben
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Original Article |
The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models
- G Cherubini
- , C Kallin
- & G Halldén
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