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Development of a stable Sf9 insect cell line to produce VSV-G pseudotyped baculoviruses
- María del Pilar Plastine
- , Sabrina Amalfi
- & Victoria Alfonso
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Article
| Open Access
Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates
- Tricia H. Burdo
- , Chen Chen
- & Kamel Khalili
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Article
| Open Access
Targeted shock-and-kill HIV-1 gene therapy approach combining CRISPR activation, suicide gene tBid and retargeted adenovirus delivery
- Sarah Klinnert
- , Corinne D. Schenkel
- & Karin J. Metzner
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Article |
Adeno-associated virus mediated expression of monoclonal antibody MR191 protects mice against Marburg virus and provides long-term expression in sheep
- Amira D. Rghei
- , Laura P. van Lieshout
- & Sarah K. Wootton
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Perspective
| Open Access
Insidious Insights: Implications of viral vector engineering for pathogen enhancement
- Jonas B. Sandbrink
- , Ethan C. Alley
- & Kevin M. Esvelt
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Article |
Biodistribution and immunity of adenovirus 5/35 and modified vaccinia Ankara vector vaccines against human immunodeficiency virus 1 clade C
- Masaru Shimada
- , Haibin Wang
- & Kenji Okuda
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Article
| Open Access
A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicity
- Winston Colon-Moran
- , Alan Baer
- & Nirjal Bhattarai
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Brief Communication
| Open Access
Novel tool to quantify with single-cell resolution the number of incoming AAV genomes co-expressed in the mouse nervous system
- Carola J. Maturana
- , Jessica L. Verpeut
- & Esteban A. Engel
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Review Article |
Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions
- Jalish M. Riyad
- & Thomas Weber
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Brief Communication |
AAV-mediated delivery of actoxumab and bezlotoxumab results in serum and mucosal antibody concentrations that provide protection from C. difficile toxin challenge
- Matthew M. Guilleman
- , Brenna A. Y. Stevens
- & Sarah K. Wootton
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Review Article |
Gene editing and RNAi approaches for COVID-19 diagnostics and therapeutics
- Burak Berber
- , Cihan Aydin
- & Cihan Tastan
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Article |
Neutralisation of adeno-associated virus transduction by human vitreous humour
- Sławomir Andrzejewski
- , Peter M. Moyle
- & Christopher J. Layton
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Article |
Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies
- Ya Li
- , Jialu Li
- & Lin Yang
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Article |
Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus
- Slawomir Andrzejewski
- , Aparna Murali
- & Christopher J. Layton
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Article |
Measles vector as a multigene delivery platform facilitating iPSC reprogramming
- Qi Wang
- , Alanna Vossen
- & Patricia Devaux
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Article |
In vivo delivery of pPERDBY to BALB/c mice by LacVax® DNA-I and comparison of elicited immune response with conventional immunization methods
- Bhrugu Yagnik
- , Drashya Sharma
- & Priti Desai
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Article |
Characterization of a replicating expanded tropism oncolytic reovirus carrying the adenovirus E4orf4 gene
- Vera Kemp
- , Iris J. C. Dautzenberg
- & Diana J. M. van den Wollenberg
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Original Article
| Open Access
Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina
- D G Hickey
- , T L Edwards
- & R E MacLaren
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Original Article |
Effects of herpes simplex virus vectors encoding poreless TRPV1 or protein phosphatase 1α in a rat cystitis model induced by hydrogen peroxide
- S Takai
- , T Majima
- & N Yoshimura
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News and Commentary |
Minority report: targeting emerging viruses before their emergence
- B D Greenbaum
- & N Vabret
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Original Article |
Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler–Najjar Syndrome Type I
- L Bočkor
- , G Bortolussi
- & A F Muro
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Original Article |
Bifidobacterium breve as a delivery vector of IL-24 gene therapy for head and neck squamous cell carcinoma in vivo
- L Wang
- , I Vuletic
- & C Guo
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Short Communication |
Use of a gamma-2 herpesvirus as a vector to deliver antibodies to rhesus monkeys
- G F Bischof
- , Y C Shin
- & R C Desrosiers
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Original Article |
Synergistic effects of deleting multiple nonessential elements in nonreplicative HSV-1 BAC genomic vectors play a critical role in their viability
- M Ventosa
- , A Ortiz-Temprano
- & F Lim
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Original Article |
Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle
- J P Gomez
- , C Gonçalves
- & P Midoux
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Original Article
| Open Access
Characterization of retroviral infectivity and superinfection resistance during retrovirus-mediated transduction of mammalian cells
- J Liao
- , Q Wei
- & J Wang
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Original Article - Enabling Technologies |
Improved gene delivery to adult mouse spinal cord through the use of engineered hybrid adeno-associated viral serotypes
- J J Siu
- , N J Queen
- & L Cao
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Original Article |
T- and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates
- C S Rollier
- , E J Verschoor
- & J L Heeney
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Original Article
| Open Access
The relevance of coagulation factor X protection of adenoviruses in human sera
- M R Duffy
- , A Doszpoly
- & A H Baker
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Original Article |
Development of an oncolytic HSV vector fully retargeted specifically to cellular EpCAM for virus entry and cell-to-cell spread
- T Shibata
- , H Uchida
- & H Tahara
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Original Article |
Treatment of colon cancer with oncolytic herpes simplex virus in preclinical models
- H Yang
- , T Peng
- & B Liu
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Original Article |
Neuroblastomas vary widely in their sensitivities to herpes simplex virotherapy unrelated to virus receptors and susceptibility
- P-Y Wang
- , H M Swain
- & T P Cripe
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Original Article |
Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs
- B Grubor-Bauk
- , W Yu
- & E J Gowans
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Original Article |
Inhalation of recombinant adenovirus expressing granulysin protects mice infected with Mycobacterium tuberculosis
- J Ma
- , J Lu
- & X Fan
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Original Article
| Open Access
Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine
- O Riede
- , K Seifert
- & C Juhls
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Original Article |
Local administration of AAV-DJ pseudoserotype expressing COX2 provided early onset of transgene expression and promoted bone fracture healing in mice
- R Lakhan
- , D J Baylink
- & X Qin
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Original Article |
Adenovirus-mediated artificial MicroRNAs targeting matrix or nucleoprotein genes protect mice against lethal influenza virus challenge
- H Zhang
- , X Tang
- & D Zhou
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Original Article |
Potent antitumor activity of Oct4 and hypoxia dual-regulated oncolytic adenovirus against bladder cancer
- C-S Lu
- , J-L Hsieh
- & A-L Shiau
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Original Article - Enabling Technologies |
Replicating reoviruses with a transgene replacing the codons for the head domain of the viral spike
- D J M van den Wollenberg
- , I J C Dautzenberg
- & R C Hoeben
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Original Article |
Impact of adenovirus life cycle progression on the generation of canine helper-dependent vectors
- P Fernandes
- , D Simão
- & P M Alves
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Short Communication |
APOBEC3A catabolism of electroporated plasmid DNA in mouse muscle
- A Kostrzak
- , M Henry
- & J-P Vartanian
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Short Communication |
Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines
- J D Jackson
- , A M McMorris
- & K A Cassady
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Short Communication |
Differential targeting of feline photoreceptors by recombinant adeno-associated viral vectors: implications for preclinical gene therapy trials
- A L Minella
- , F M Mowat
- & S M Petersen-Jones
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Original Article |
Retinal transduction profiles by high-capacity viral vectors
- A Puppo
- , G Cesi
- & A Auricchio
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Original Article |
Vero/BC-F: an efficient packaging cell line stably expressing F protein to generate single round-infectious human parainfluenza virus type 2 vector
- J Ohtsuka
- , M Fukumura
- & T Nosaka
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Original Article
| Open Access
Long-term functional duration of immune responses to HCV NS3/4A induced by DNA vaccination
- G Ahlén
- , F Holmström
- & L Frelin
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Original Article |
Mammalian orthoreovirus T3D infects U-118 MG cell spheroids independent of junction adhesion molecule-A
- I J C Dautzenberg
- , D J M van den Wollenberg
- & R C Hoeben
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Original Article |
Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve
- S A Hoyng
- , S Gnavi
- & J Verhaagen
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Short Communication |
Activity of a group B oncolytic adenovirus (ColoAd1) in whole human blood
- Y Di
- , L Seymour
- & K Fisher
AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumoniaBrowse broader subjects
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