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| Open AccessSelective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum
- Charisse Flerida A. Pasaje
- , Vanessa Cheung
- & Stuart A. Ralph
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| Open AccessAccumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2
- Yaling Yin
- , Yali Wang
- & Jian-Zhi Wang
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| Open AccessTruncated Variants of Gaussia Luciferase with Tyrosine Linker for Site-Specific Bioconjugate Applications
- Eric A. Hunt
- , Angeliki Moutsiopoulou
- & Sapna K. Deo
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| Open Access(±)-Japonones A and B, two pairs of new enantiomers with anti-KSHV activities from Hypericum japonicum
- Linzhen Hu
- , Hucheng Zhu
- & Yonghui Zhang
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| Open AccessPenicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., isolated from the Rhizosphere Soil of Panax notoginseng
- Ya-Nan An
- , Xue Zhang
- & Xin-Sheng Yao
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| Open AccessPeptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3′,5′difluorophenyl)-alanine
- Pablo Martín-Gago
- , Álvaro Rol
- & Antoni Riera
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| Open AccessSesterterpene ophiobolin biosynthesis involving multiple gene clusters in Aspergillus ustus
- Hangzhen Chai
- , Ru Yin
- & Kui Hong
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| Open AccessChalcone-based Selective Inhibitors of a C4 Plant Key Enzyme as Novel Potential Herbicides
- G. T. T. Nguyen
- , G. Erlenkamp
- & G. Groth
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| Open AccessA metabolomics cell-based approach for anticipating and investigating drug-induced liver injury
- Juan Carlos García- Cañaveras
- , José V. Castell
- & Agustín Lahoz
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| Open AccessA carnosine intervention study in overweight human volunteers: bioavailability and reactive carbonyl species sequestering effect
- Luca Regazzoni
- , Barbora de Courten
- & Giancarlo Aldini
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| Open AccessA sacrificial millipede altruistically protects its swarm using a drone blood enzyme, mandelonitrile oxidase
- Yuko Ishida
- , Yasumasa Kuwahara
- & Yasuhisa Asano
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| Open AccessNon-random distribution of homo-repeats: links with biological functions and human diseases
- Michail Yu. Lobanov
- , Petr Klus
- & Oxana V. Galzitskaya
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| Open AccessUnexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7
- Menachem J. Gunzburg
- , Ketav Kulkarni
- & Jacqueline A. Wilce
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Article
| Open AccessThe phosphatidylethanolamine derivative diDCP-LA-PE mimics intracellular insulin signaling
- Tomoyuki Nishizaki
- , Akinobu Gotoh
- & Akito Tanaka
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| Open AccessThe origin of the cooperativity in the streptavidin-biotin system: A computational investigation through molecular dynamics simulations
- Fengjiao Liu
- , John Z. H. Zhang
- & Ye Mei
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| Open AccessRapid and sensitive detection of early esophageal squamous cell carcinoma with fluorescence probe targeting dipeptidylpeptidase IV
- Haruna Onoyama
- , Mako Kamiya
- & Yasuyuki Seto
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Article
| Open AccessRegulating the effects of GPR21, a novel target for type 2 diabetes
- Siobhán Leonard
- , Gemma K. Kinsella
- & John B. C. Findlay
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Article
| Open AccessFatty acid profile in the seeds and seed tissues of Paeonia L. species as new oil plant resources
- Shuiyan Yu
- , Shaobo Du
- & Yonghong Hu
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Article
| Open AccessA highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative
- Boglárka H. Várkuti
- , Miklós Képiró
- & András Málnási-Csizmadia
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Article
| Open AccessLanthanum induced B-to-Z transition in self-assembled Y-shaped branched DNA structure
- Ashok K. Nayak
- , Aseem Mishra
- & Umakanta Subudhi
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Article
| Open AccessIdentification of lactate dehydrogenase as a mammalian pyrroloquinoline quinone (PQQ)-binding protein
- Mitsugu Akagawa
- , Kenji Minematsu
- & Koji Uchida
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Article
| Open AccessVitamin k3 inhibits protein aggregation: Implication in the treatment of amyloid diseases
- Parvez Alam
- , Sumit Kumar Chaturvedi
- & Rizwan Hasan Khan
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Article
| Open AccessStructural characterization of CYP144A1 – a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis
- Jude Chenge
- , Madeline E. Kavanagh
- & Andrew W. Munro
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| Open AccessIntegrated Microfluidic Isolation of Aptamers Using Electrophoretic Oligonucleotide Manipulation
- Jinho Kim
- , Timothy R. Olsen
- & Qiao Lin
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| Open AccessAn inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis
- Meng-Chen Lu
- , Jian-Ai Ji
- & Zheng-Yu Jiang
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| Open AccessTwo-Photon Enzymatic Probes Visualizing Sub-cellular/Deep-brain Caspase Activities in Neurodegenerative Models
- Linghui Qian
- , Cheng-Wu Zhang
- & Shao Q. Yao
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| Open AccessProteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival
- Tatsuro Kawamura
- , Makoto Kawatani
- & Hiroyuki Osada
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| Open AccessVasoactive Intestinal Peptide modulates trophoblast-derived cell line function and interaction with phagocytic cells through autocrine pathways
- Daiana Vota
- , Daniel Paparini
- & Claudia Pérez Leirós
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| Open AccessCell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells
- Ji heon Rhim
- , Xiangjian Luo
- & Xiaofeng Xia
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Article
| Open AccessDistinctive proteomic profiles among different regions of human carotid plaques in men and women
- Wenzhao Liang
- , Liam J. Ward
- & Xi-Ming Yuan
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| Open AccessEffect of Exercise and Calorie Restriction on Tissue Acylcarnitines, Tissue Desaturase Indices, and Fat Accumulation in Diet-Induced Obese Rats
- Venkatesh Gopalan
- , Navin Michael
- & S. Sendhil Velan
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| Open AccessPrevention of antipsychotic-induced hyperglycaemia by vitamin D: a data mining prediction followed by experimental exploration of the molecular mechanism
- Takuya Nagashima
- , Hisashi Shirakawa
- & Shuji Kaneko
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| Open AccessAn in vivo invertebrate evaluation system for identifying substances that suppress sucrose-induced postprandial hyperglycemia
- Yasuhiko Matsumoto
- , Masaki Ishii
- & Kazuhisa Sekimizu
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| Open AccessProteome-wide drug screening using mass spectrometric imaging of bead-arrays
- Ying Zhou
- , Ziying Liu
- & Mark J. Lim
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| Open AccessNovel small molecule 11β-HSD1 inhibitor from the endophytic fungus Penicillium commune
- Weiguang Sun
- , Xintao Chen
- & Yonghui Zhang
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Article
| Open AccessBioactivity of 2′-deoxyinosine-incorporated aptamer AS1411
- Xinmeng Fan
- , Lidan Sun
- & Zhenjun Yang
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| Open AccessMechanistic insight into cadmium-induced inactivation of the Bloom protein
- Wei Qin
- , Nicolas Bazeille
- & Xu-Guang Xi
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Article
| Open AccessA novel pathway for fungal D-glucuronate catabolism contains an L-idonate forming 2-keto-L-gulonate reductase
- Joosu Kuivanen
- , Maura H. Sugai-Guérios
- & Peter Richard
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| Open AccessMetabolomics Investigation Reveals Metabolite Mediators Associated with Acute Lung Injury and Repair in a Murine Model of Influenza Pneumonia
- Liang Cui
- , Dahai Zheng
- & Choon Nam Ong
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| Open AccessVisible-light photoredox synthesis of unnatural chiral α-amino acids
- Min Jiang
- , Yunhe Jin
- & Hua Fu
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| Open AccessCombination of deep eutectic solvent and ionic liquid to improve biocatalytic reduction of 2-octanone with Acetobacter pasteurianus GIM1.158 cell
- Pei Xu
- , Peng-Xuan Du
- & Wen-Yong Lou
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Article
| Open AccessRegulation of Irregular Neuronal Firing by Autaptic Transmission
- Daqing Guo
- , Shengdun Wu
- & Dezhong Yao
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Article
| Open AccessImaging of Cerebral Amyloid Angiopathy with Bivalent 99mTc-Hydroxamamide Complexes
- Shimpei Iikuni
- , Masahiro Ono
- & Hideo Saji
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Article
| Open AccessRinghalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex
- Bhaskar Barnwal
- , Chacko Jobichen
- & R. Manjunatha Kini
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Article
| Open AccessApplication of iridium(III) complex in label-free and non-enzymatic electrochemical detection of hydrogen peroxide based on a novel “on-off-on” switch platform
- Xiangmin Miao
- , Chao Yang
- & Dik-Lung Ma
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Article
| Open AccessStructural investigation into physiological DNA phosphorothioate modification
- Wenxian Lan
- , Zhongpei Hu
- & Chunyang Cao
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Article
| Open AccessMuc5ac gastric mucin glycosylation is shaped by FUT2 activity and functionally impacts Helicobacter pylori binding
- Ana Magalhães
- , Yannick Rossez
- & Celso A. Reis
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Article
| Open AccessBRAID: A Unifying Paradigm for the Analysis of Combined Drug Action
- Nathaniel R. Twarog
- , Elizabeth Stewart
- & Anang A. Shelat
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| Open AccessN6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
- Shui Zou
- , Joel D. W. Toh
- & Esther C. Y. Woon
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