Correspondence |
Featured
-
-
-
News & Views |
Organ recital in a dish
It is difficult to recapitulate organ development in vitro, especially when interactions between tissues are essential. Nonetheless, researchers have now achieved this for the pituitary gland. See Article p.57
- Karine Rizzoti
- & Robin Lovell-Badge
-
Letter |
Antibody-based protection against HIV infection by vectored immunoprophylaxis
A single injection of a viral vector that encodes antibodies able to neutralize most HIV strains protects humanized mice from HIV infection.
- Alejandro B. Balazs
- , Joyce Chen
- & David Baltimore
-
News |
Dynamic duo helps to heal irradiated mice
Protein and antibiotic treatment works even 24 hours after exposure.
- Lucas Laursen
-
News |
Bioengineers debate use of military money
US Department of Defense’s call for greener ways to make explosives worries synthetic biologists.
- Erika Check Hayden
-
Letter |
Lyn is a redox sensor that mediates leukocyte wound attraction in vivo
The Src family kinase Lyn is identified as a physiological redox sensor that mediates the initial attraction of leukocytes to wounds in zebrafish larvae.
- Sa Kan Yoo
- , Taylor W. Starnes
- & Anna Huttenlocher
-
Research Highlights |
Safety switch for cell therapy
-
News |
Rice seed yields blood protein
Human serum albumin from transgenic rice could ease shortages of donated blood.
- Lauren Gravitz
-
Books & Arts |
Biotechnology: DNA dollars
Linnaea Ostroff examines a history of Genentech, the US company that first made biology a business.
- Linnaea Ostroff
-
News |
Antibody offers hope for multiple sclerosis treatment
Promising phase III trial paves the way for alemtuzumab approval.
- Duncan Graham-Rowe
-
Letter |
Biomimetic self-templating supramolecular structures
- Woo-Jae Chung
- , Jin-Woo Oh
- & Seung-Wuk Lee
-
Letter |
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
- Katey J. Rayner
- , Christine C. Esau
- & Kathryn J. Moore
-
News |
European court bans patents based on embryonic stem cells
Final decision could stifle investment in developing therapies.
- Ewen Callaway
-
News |
No quick fix for Haiti cholera
As outbreak enters its second year, relief bodies move to roll out vaccine for the first time.
- Declan Butler
-
Books & Arts |
Bioethics: Brave new biopolitics
Kevin Finneran hails a timely take on the debate raging over biotechnology breakthroughs in the United States.
- Kevin Finneran
-
Letter |
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
- Kosuke Yusa
- , S. Tamir Rashid
- & Ludovic Vallier
-
Research Highlights |
'Braille code' for cell growth
-
News |
Cloned human embryo makes working stem cells
Researchers begin to identify past problems with cloning technique.
- David Cyranoski
-
Letter |
Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy
- Mariko Taniguchi-Ikeda
- , Kazuhiro Kobayashi
- & Tatsushi Toda
-
News |
'Patent trolls' target biotechnology firms
Opportunistic patent litigation threatens the life sciences.
- Erika Check Hayden
-
-
Research Highlights |
Heart attack hits bone marrow
-
Brief Communications Arising |
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
- Mohan Viswanathan
- & Leonard Guarente
-
News |
Texas prepares to fight for stem cells
Enthusiasm for unapproved treatments worries regulators.
- David Cyranoski
-
Research Highlights |
Mobile imaging of the mouse brain
-
News |
Electrified bacterial filaments zap uranium
Mechanism by which microbes scrub radioactive contamination revealed.
- Lee Sweetlove
-
Research Highlights |
Bacteria engineered to kill
-
Feature |
Florida: Second thoughts
The sunshine state's rush to become a bioscience player started with a bang. Now it faces more realistic expectations.
- Sarah Kellogg
-
News & Views |
Tumour-fighting virus homes in
An early clinical trial demonstrates the delivery and replication of a cancer-killing virus in metastasized tumour tissue. These promising results could provide a foundation for systemic virotherapy for patients with cancer. See Letter p.99
- Evanthia Galanis
-
News |
Britain to launch personalized medicine project
Pilot programme will combine genetic tests with centralized data.
- Daniel Cressey
-
News |
Gene-therapy successes spur hope for embattled field
Technique now being tested in a range of conditions.
- Erika Check Hayden
-
Editorial |
Start small, think big
The United Kingdom and others must not overlook the potential for nanotechnology to boost regenerative medicine.
-
-
News |
Set a bug to kill a bug
Engineered bacteria attack lethal infection with its own weapons.
- Marian Turner
-
Correspondence |
Helping hand for genomics in Africa
- Vanessa M. Hayes
- , Philip A. Venter
- & M. Jeffrey Mphahlele
-
News & Views |
Bespoke cells for the human brain
Human skin cells have been directly converted into neurons, an achievement that could lead to the cell-based treatment of neurodegenerative disorders. But the road ahead remains long and tortuous. See Letters p.220, p.224 & p.228
- Michael Sendtner
-
News |
Cell therapy fights leukaemia
Patchwork receptors target immune cells against cancer.
- Heidi Ledford
-
Letter |
Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals
- Clementina Dellomonaco
- , James M. Clomburg
- & Ramon Gonzalez
-
News |
Gene-therapy enzymes make unpredicted errors
Techniques show mistakes of 'highly specific' molecular tools.
- Heidi Ledford
-
News |
One antibody to bind them all
An antibody that recognizes all strains of influenza A could be a universal vaccine blueprint.
- Marian Turner
-
Research Highlights |
Customer data aid Parkinson's study
-
Research Highlights |
Edited stem cells yield healthy mice
-
News |
Injectable implant to help doctors save face
Light-activated polymer may provide non-invasive method of soft-tissue reconstruction.
- George Wigmore
-
News |
Genome giant offers data service
Chinese sequencing institute launches remote computing networks to crunch DNA data.
- Ewen Callaway
-
Editorial |
The legacy of Doctor Moreau
Regulators must look past visceral disgust about human–animal hybrids. Strict but sensible rules are needed for research on hybrid embryos and chimaeric animals that could produce therapies.
-
Comment |
Regulate research at the animal–human interface
The time is right, says Martin Bobrow, to improve the governance of research involving animals that contain human genetic or cellular material.
- Martin Bobrow
-
News |
Regulations proposed for animal–human chimaeras
UK lays out first framework to govern ethically sensitive research field.
- Alison Abbott
-
Article
| Open AccessAn integrated semiconductor device enabling non-optical genome sequencing
- Jonathan M. Rothberg
- , Wolfgang Hinz
- & James Bustillo
-
News |
Genomes edited to free up codons
Redundant sequences could be used to encode artificial amino acids.
- Gwyneth Dickey Zakaib
Browse broader subjects
Browse narrower subjects
- Animal biotechnology
- Applied immunology
- Assay systems
- Biologics
- Biomaterials
- Biomimetics
- Cell delivery
- Environmental biotechnology
- Expression systems
- Functional genomics
- Gene delivery
- Gene therapy
- Genomics
- Industrial microbiology
- Metabolic engineering
- Metabolomics
- Molecular engineering
- Nanobiotechnology
- Nucleic-acid therapeutics
- Oligo delivery
- Peptide delivery
- Plant biotechnology
- Protein delivery
- Proteomics
- Regenerative medicine
- Sequencing
- Stem-cell biotechnology
- Tissue engineering