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In this Journal Club, Rebecca Shapiro discusses the discovery of the earliest antifungal drug, nystatin, by pioneering women Elizabeth Hazen and Rachel Brown.
In this Journal Club, Tao Zuo discusses a study by Gogokhia et al. who found that gut bacteriophages can alter mucosal immunity to impact mammalian health.
In this Journal Club, Sarah Auburn discusses the pioneering development of the first framework for whole-genome sequencing of natural malaria infections, revolutionizing malaria genomics.
In this Review, He and co-workers explore the structure and diversity of the oral microbiota, and they discuss the role of the oral microbiota in the pathology of both oral and systemic diseases.
In this Review, Rillig, Kim and Zhu review our current understanding of the soil plastisphere, including the members of the microbial community that are enriched, the possible mechanisms underpinning this selection and functional properties.
In this Review, Lass-Flörl and Govrins explore the epidemiology, clinical manifestations and antifungal resistance of the Candida parapsilosis complex, and discuss diagnostics and new treatment approaches to tackle infections by these human pathogens.
This study shows that intercellular long extensions promote the evasion of antibody neutralization and the efficient intercellular transmission of chikungunya virus in vitro and in vivo.
This month’s Genome Watch highlights the use of high-depth genome-centric approaches to further our understanding of the human gut microbiome within the context of industrialized and non-industrialized lifestyles.
In this Review, Maillard and Pascoe examine the mechanisms of action of biocides, as well as the bacterial intrinsic and acquired resistance to these biocides and its implications in environmental and clinical settings.
In this Review, Lockhart, Chowdhary and Gold discuss the global emergence and spread of three emerging antifungal-resistant fungi: Candida auris, azole-resistant Aspergillus fumigatus and Trichophyton indotineae, with the common thread that all three are currently emerging across the globe and have a high rate of acquired resistance.
This Genome Watch highlights how the integration of genomic surveillance with epidemiological or clinical data can help understand pathogen transmission and improve public health interventions for infectious disease control.
In this study, Huang et al. discover Delftia tsuruhatensis TC1, a mosquito symbiotic bacterium that inhibits parasite development via the secretion of a small molecule.
In this study, Sharafutdinov et al. report a single nucleotide polymorphism in the gene encoding the HtrA protease of Helicobacter pylori that is associated with gastric cancer.
In this Review, de Nies, Kobras and Stracy examine the detrimental effects of antibiotics on the microbiota and the resulting associated infections. They delve into the interplay between antibiotic therapy, loss of colonization resistance, overgrowth of resistant bacteria and subsequent infections. They also discuss strategies to mitigate these risks and reduce antibiotic-associated infections.
In this Review, Russell and colleagues explore the interplay between immunity evolution from previous infections or vaccination and the evolution of seasonal influenza viruses. They explore functional constraints that limit virus evolution, within-host evolutionary processes that drive new variants and options for influenza virus control, including improving vaccine and antiviral effectiveness by overcoming viral and immunological barriers.
In this Review, Margolin and Cameron explore how the divisome of Escherichia coli is assembled and activated to modulate the division process, and discuss how the divisome machinery can be targeted for therapeutic purposes.
The forthcoming UN summit marks the halfway point to 2030 and presents an important milestone in global efforts to address various challenges, including those related to climate change and environmental preservation. The UN SDGs include several related to microorganisms and climate change. Microbiology research is key to understanding and mitigating climate change, and in maintaining the health of terrestrial and aquatic ecosystems (SDGs 13, 14 and 15).
