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Volume 19 Issue 12, December 2023

Wrinkling suppression in the cell nucleus

The wrinkling of the membrane that contains the cell nucleus as it develops is associated with ageing and disease. Jonathan Jackson and colleagues show that this nuclear wrinkling in the development of fruit fly eggs can be manipulated through osmotic shocks and microtubule inhibition. Indeed, wrinkling can even be reversed, allowing tunable control over the mechanical properties of the membrane.

See Jackson et al.

Image: Nicolas Romeo and Jonathan Jackson, Massachusetts Institute of Technology. Cover Design: Amie Fernandez

Editorial

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News & Views

  • Measurements of two neighbouring silicon-based qubits show that the charge noise they each experience is correlated, suggesting a common origin. Understanding these correlations is crucial for performing error correction in these systems.

    • Łukasz Cywiński
    News & Views
  • The simulation of open quantum many-body systems is one of the hardest tasks in computational physics. Now, quantum computers are close to answering crucial questions for such systems in a regime that classical computers cannot reach.

    • Hendrik Weimer
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  • Understanding the mechanism underlying light-induced superconductivity could help manifest it at higher temperatures. Experiments now show that the excitation of a specific phonon leads to a resonant enhancement of this effect in K3C60.

    • Jingdi Zhang
    News & Views
  • Understanding lattice-geometry-driven electronic structure and orbital character in a titanium-based superconducting kagome metal provides insights into the non-trivial topology and electronic nematicity of correlated quantum matter.

    • Bahadur Singh
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  • A trilayer copper oxide superconductor, which exhibits the highest superconducting critical temperature as a function of the number of copper–oxygen planes, is shown to have unusual doped hole distribution and interaction between the planes.

    • Atsushi Fujimori
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  • Hubbard excitons are elusive quasiparticles that are predicted to form in strongly correlated insulators. Detecting their internal structure and dynamics clarifies the involvement of spin fluctuations in their binding and recombination processes.

    • Edoardo Baldini
    News & Views
  • Disordered systems that are far from equilibrium relax slowly towards their equilibrium. Now, we learn that the irreversible plastic deformations that form the wrinkles of a crumpled sheet result in a complex energy landscape that ages logarithmically.

    • Kari Dalnoki-Veress
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  • Permanent deformation in solids results from atoms not aligning with the external stress causing the deformation. Detecting such non-affine atomic rearrangements and connecting them to measurable mechanical effects is now shown to be feasible by means of high-energy X-ray diffraction.

    • Saswati Ganguly
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  • The liquid-crystal-like order of cells in epithelial tissues aids rearrangements, but there is disagreement over the dominant liquid crystal phase. Now, a unified approach reveals that two distinct symmetries dominate at different scales.

    • Daniel Beller
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Research Briefings

  • Local thermodynamic measurements of a twisted transition metal dichalcogenide heterostructure reveal competition between unconventional charge order and Hofstadter states. This results from the presence of both flat and dispersive electronic bands, whose energetic ordering can be experimentally tuned.

    Research Briefing
  • An approach combining single-cell imaging, agent-based simulations, and continuum mechanics theory is used to observe the effect of environmental stiffness on biofilm development. These measurements indicate that confined biofilms behave as active nematics, in which the internal organization and cell lineage are controlled by the shape and boundary of the biofilm.

    Research Briefing
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Letters

  • Cells in a tissue layer arrange themselves in orientationally ordered structures. Now two types of liquid crystalline order have been shown to coexist, with nematic order dominating large length scales and hexatic order dominating small length scales.

    • Josep-Maria Armengol-Collado
    • Livio Nicola Carenza
    • Luca Giomi
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Articles

  • Physical realizations of qubits are often vulnerable to leakage errors, where the system ends up outside the basis used to store quantum information. A leakage removal protocol can suppress the impact of leakage on quantum error-correcting codes.

    • Kevin C. Miao
    • Matt McEwen
    • Yu Chen
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  • Errors in a quantum computer that are correlated between different qubits pose a considerable challenge for correction schemes. Measurements of noise in silicon spin qubits show that electric field fluctuations can create strongly correlated errors.

    • J. Yoneda
    • J. S. Rojas-Arias
    • S. Tarucha
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  • Quantum computers may help to solve classically intractable problems, such as simulating non-equilibrium dissipative quantum systems. The critical dynamics of a dissipative quantum model has now been probed on a trapped-ion quantum computer.

    • Eli Chertkov
    • Zihan Cheng
    • Michael Foss-Feig
    Article
  • Observations of the conversion of orbital angular momentum into charge indicate that the orbital degree of freedom can provide a channel for information storage and processing.

    • Anas El Hamdi
    • Jean-Yves Chauleau
    • Michel Viret
    Article
  • Many complex systems relax slowly towards equilibrium after a perturbation, without ever reaching it. Experiments with crumpled sheets now show that these relaxations involve intermittent avalanches of localized instabilities, whose slow-down leads to logarithmic aging.

    • Dor Shohat
    • Yaniv Friedman
    • Yoav Lahini
    Article
  • The Magnus effect refers to rotating objects developing a lift force when travelling through a fluid. It normally vanishes at microscopic length scales but now a very large Magnus effect is demonstrated for spinning colloids in viscoelastic fluids.

    • Xin Cao
    • Debankur Das
    • Clemens Bechinger
    Article Open Access
  • The boson peak refers to an excess in the phonon density of states seen in three-dimensional amorphous materials. Helium-atom scattering experiments have now revealed a boson peak in a two-dimensional material, too, at a frequency similar to that of the bulk material.

    • Martin Tømterud
    • Sabrina D. Eder
    • Bodil Holst
    Article
  • Filaments of the FtsZ protein can form chiral assemblies. Now, active matter tools link the microscopic structure of active filaments to the large-scale collective phase of these assemblies.

    • Zuzana Dunajova
    • Batirtze Prats Mateu
    • Martin Loose
    Article Open Access
  • Wrinkling of cell nuclei is associated with disease. During development, the nucleus behaves like a sheet of paper and the wrinkling amplitude can be manipulated without changing its pattern.

    • Jonathan A. Jackson
    • Nicolas Romeo
    • Jasmin Imran Alsous
    Article
  • Confined biofilms can shape themselves and their boundary to modify their internal organisation. This mechanism could inform the development of active materials that control their own geometry.

    • Japinder Nijjer
    • Changhao Li
    • Jing Yan
    Article
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Amendments & Corrections

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Measure for Measure

  • The hectare has a long association with the metric system, but its most recent status has created some ambiguity as to its future application. Richard Brown surveys the lay of the land.

    • Richard J. C. Brown
    Measure for Measure
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