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Dendritic cells in the process of delivering internalized antigen to the cytosol. Cells internalized antigen for 1 h. The middle and lower cells were then incubated for 3 or 6 h more, respectively, at 37°C. Staining was with anti-rabbit IgG (green) for internalized antigen and lysotracker (red) for acidic endocytic compartments.Yellow indicates presence of antigen in acidic vesicles. [Cover design: Majo Xeridat] [article, p.362.; news and views, p. E152.]