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Using meta-analytic techniques, authors report patterns of aberrant functional brain associated with differences in neurophysiology and cognitive and behavioral regulatory mechanisms in men diagnosed with pedophilic disorder to elucidate potential mechanistic and pharmacological interventions.
In a sample of children and adolescents aged 11–16 years old, authors used plasma-based proteomic techniques to identify biomarkers associated with risk for developing a mental health disorder.
Hu et al. performed a network analysis to investigate the relationship between a two-factor model of negative symptoms, social functioning and other psychopathological symptoms in a transdiagnostic sample of patients with major depression, schizophrenia and bipolar disorder.
Using a sample of over 4,900 adolescents, Westwater et al. show that genetic risk for anorexia nervosa and high body mass have distinct associations with brain structure and psychopathology symptoms related to eating disorders.
Cocchi and coauthors report that continuous theta burst stimulation of the frontal pole shows no difference from sham in reducing symptoms of obsessive-compulsive disorder or frontostriatal connectivity.
In this analysis of data from the Healthy Minds Study of over 200,000 college students in the United States, the authors found greater levels of depressive and anxiety symptoms and sexual violence and assaults experienced by gender and sexual minorities during the pandemic. These findings reinforce the disproportionate and heightened mental health and sexual violence risks for gender and sexual minority youth and the need to increase on-campus safety and crisis intervention.
Galante et al. performed a systematic review and meta-analysis using individual participant data from randomized controlled trials evaluating mindfulness-based programs for adult mental health promotion in non-clinical settings.
In this secondary analysis of a clinical trial exploring the efficacy of Mindfulness-Oriented Recovery Enhancement (MORE) versus supportive group psychotherapy for reducing post-traumatic stress disorder (PTSD) symptoms in patients with chronic pain receiving opioid treatment, the authors demonstrate that increased cognitive reappraisal mediated reduced PTSD symptoms and opioid misuse after the MORE intervention.
In this paper describing the impact of the coronavirus disease 2019 pandemic on a large public mental health system, the authors examined the availability and service uptake of telepsychiatry over 2 years in a regional network of community mental health centres covering approximately 10 million people in Italy.
Kozák and colleagues use routinely collected data from more than 500,000 Norwegian adolescents to examine the effects before, during and after the COVID-19 pandemic on well-being and explore the impact of social inequality.
In this longitudinal study, Bernasconi and colleagues explore the association of minor hallucinations and theta oscillations with the future occurrence of cognitive decline in patients with early Parkinson’s disease.
Using data from a large US population survey, Choi et al. investigated the nuanced associations between perceived social support and the risk for depression during the COVID-19 pandemic.
Yang et al. used longitudinal data from a large US cohort to investigate the association between childhood asthma, allergies and premenstrual disorders in young adulthood.
Using a placebo-controlled, randomized crossover design, authors demonstrate that intranasal oxytocin modulated the processing of fearful facial expressions during an fMRI task in adults with antisocial personality disorder with psychopathy.
This large study, conducted in school-aged children in China, evaluates the relationship between long-term exposure to ambient particulate matter and positive screening for attention deficit hyperactivity disorder (ADHD). The authors report stronger associations between ADHD and PM1 exposure than between ADHD and PM2.5.
Nord and coauthors performed a meta-analysis to identify the degree to which specific biological, psychological or somatic interventions used as acute augmentation of psychological therapy further reduced psychiatric symptoms, demonstrating that various types of acute augmentations (such as pharmacological augmentations) were effective but to varying degrees.
In a large international survey, a minority subset of individuals with Long COVID experienced greater psychiatric symptom severity that was associated with greater reductions in overall health and other specific outcomes.
Panayiotou et al. performed a panel network analysis to investigate the relationship between time spent on social media and mental health in a large cohort of UK adolescents.
Using a transdiagnostic approach, Hoven et al. investigated the relationship between self-reported psychiatric symptoms and metacognition, from confidence to self-beliefs.
In this study, Mandelli et al. identify early snapshot subtypes of autism spectrum disorder based on adaptive functioning, and propose a predictive model for developmental trajectories in non-verbal cognitive, language and motor domains.